ADVANCED PATHOPHYSIOLOGY
MIDTERM EXAM WITH 100%
VERIFIED SOLUTIONS 2024/2025
A runner has depleted all the oxygen available for muscle energy.
Which of the following will facilitate his con;nued muscle
performance?
Answer: anaerobic glycolysis
What causes the rapid change in the res;ng membrane poten;al that
ini;ates an ac;on poten;al?
Answer: sodium gates open, and sodium rushes into the cell,
changing the membrane poten;al from nega;ve to posi;ve.
A 12-year-old male is diagnosed with klinefelter syndrome. His
karyotype would reveal which of the following?
Answer: xxy
A nurse is reviewing the pedigree chart. When checking for a
proband, what is the nurse looking for?
Answer: the person who is first diagnosed with a gene;c disease
An aide asks the nurse why people who have neurofibromatosis will
show varying degrees of the disease. Which gene;c principle should
the nurse explain to the aide?
Answer: expressivity
, In teaching a pa;ent with cirrhosis, which informa;on should the
nurse include regarding cholesterol?
Answer: cholesterol decreases the membrane fluidity of the
erythrocyte, which reduces its ability to carry oxygen.
When a pa;ent asks what causes cys;c fibrosis, how should the
nurse respond? Cys;c fibrosis is caused by an _____ gene
Answer: autosomal recessive
How are potassium and sodium transported across plasma
membranes?
Answer: by adenosine triphosphate enzyme (atpase)
The nurse would be correct in iden;fying the predominant
extracellular ca;on as:
Answer: sodium
The early dila;on (swelling) of the cell's endoplasmic re;culum
results in:
Answer: reduced protein synthesis
What principle should the nurse remember when trying to
dis;nguish aging from diseases?
Answer: it is difficult to tell the difference because both processes are
believed to result from cell injury.
What is the diagnosis of a 13-year-old female who has a karyotype
that reveals an absent homologous x chromosome with only a single
x chromosome present? Her features include a short stature, widely