NU 641 Advanced Pharm (for NPs) Vaccines questions
with correct answers
Live Attenuated vaccines general principles Correct Answer-Not
administered to immunocompromised patients
Usually not given if patient has febrile illness
If patient needs two live vaccines: Correct Answer-Give both the same
day OR
Administer at least 4 weeks apart
Can live attenuated vaccine be administered in pregnancy? Correct
Answer-Not administered in pregnancy
Pregnancy should be avoid for 1 month after vaccination
Drug interaction with live attenuated vaccine? Correct Answer-Antiviral
drugs
List of live attenuated vaccines? Correct Answer-Live Attenuated
Influenza Vaccine (Flumist)
Measles, Mumps, and Rubella Vaccine (MMR)
Oral Poliovirus Vaccine (OPV) -no longer used in US
Rotavirus Vaccine (Rotarix, RotaTeq)
Varicella Virus Vaccine (Varivax, ProQuad)
Herpes Zoster Vaccine (Zostavax)
,LAIV (Flumist)
what are the two types of live Attenuated Influenza Vaccine? Correct
Answer-Was trivalent and Quadrivalent (February 2012)
2013-2014 flu season only available as Quadrivalent
Trivalent - Correct Answer-Contains 2 strains of Influenza A and 1
strain of influenza B
Quadrivalent - Correct Answer-Contains 2 strains of Influenza A and 2
strains of influenza B
How is LAIV (Flumist) administered? Correct Answer-Administered
intranasally (half in each nostril)
Live vaccine replicates in nasal mucosa
Administer to healthy patients age 2 yrs to 49 yrs annually
Children age 2 to 8 years need typically need 2 doses (4 weeks apart) 1st
year - refer to guidelines
LAIV (Flumist) contraindications? Correct Answer-Contraindicated:
Egg allergy, asthma, immunocompromised, pregnancy, lactation
(possibility of viral shed in breast milk)
Measles, Mumps & Rubella (MMR) Correct Answer-2 doses 99%
effective in providing immunity
, Contraindications for MMR: Correct Answer-neomycin or gelatin
allergy, pregnancy (within 3 months of vaccine), immunosuppression,
febrile illness
May be given to close contact of immunosuppressed patients
Wait 3 months from receiving blood products
can MMR be given to pt with egg allergy? Correct Answer-Ok to give
with egg allergy
MMR and breastfeeding Correct Answer-May give to breastfeeding
women
ADRs of MMR Correct Answer-Fever 7 to 12 days after vaccination
Transient maculopapular rash 7-10 days after vaccination in 5% of
patients
MMR drug interactions Correct Answer-Immunosupressents including
high dose corticosteroids and chemotherapy
Immune globulin - can inactivate vaccine
PPD - delayed 4 to 6 weeks after MMR - - may interfere with the
tuberculin skin test
At what age is first MMR administered? Correct Answer-Administer
first dose at age 12 to 15 months
with correct answers
Live Attenuated vaccines general principles Correct Answer-Not
administered to immunocompromised patients
Usually not given if patient has febrile illness
If patient needs two live vaccines: Correct Answer-Give both the same
day OR
Administer at least 4 weeks apart
Can live attenuated vaccine be administered in pregnancy? Correct
Answer-Not administered in pregnancy
Pregnancy should be avoid for 1 month after vaccination
Drug interaction with live attenuated vaccine? Correct Answer-Antiviral
drugs
List of live attenuated vaccines? Correct Answer-Live Attenuated
Influenza Vaccine (Flumist)
Measles, Mumps, and Rubella Vaccine (MMR)
Oral Poliovirus Vaccine (OPV) -no longer used in US
Rotavirus Vaccine (Rotarix, RotaTeq)
Varicella Virus Vaccine (Varivax, ProQuad)
Herpes Zoster Vaccine (Zostavax)
,LAIV (Flumist)
what are the two types of live Attenuated Influenza Vaccine? Correct
Answer-Was trivalent and Quadrivalent (February 2012)
2013-2014 flu season only available as Quadrivalent
Trivalent - Correct Answer-Contains 2 strains of Influenza A and 1
strain of influenza B
Quadrivalent - Correct Answer-Contains 2 strains of Influenza A and 2
strains of influenza B
How is LAIV (Flumist) administered? Correct Answer-Administered
intranasally (half in each nostril)
Live vaccine replicates in nasal mucosa
Administer to healthy patients age 2 yrs to 49 yrs annually
Children age 2 to 8 years need typically need 2 doses (4 weeks apart) 1st
year - refer to guidelines
LAIV (Flumist) contraindications? Correct Answer-Contraindicated:
Egg allergy, asthma, immunocompromised, pregnancy, lactation
(possibility of viral shed in breast milk)
Measles, Mumps & Rubella (MMR) Correct Answer-2 doses 99%
effective in providing immunity
, Contraindications for MMR: Correct Answer-neomycin or gelatin
allergy, pregnancy (within 3 months of vaccine), immunosuppression,
febrile illness
May be given to close contact of immunosuppressed patients
Wait 3 months from receiving blood products
can MMR be given to pt with egg allergy? Correct Answer-Ok to give
with egg allergy
MMR and breastfeeding Correct Answer-May give to breastfeeding
women
ADRs of MMR Correct Answer-Fever 7 to 12 days after vaccination
Transient maculopapular rash 7-10 days after vaccination in 5% of
patients
MMR drug interactions Correct Answer-Immunosupressents including
high dose corticosteroids and chemotherapy
Immune globulin - can inactivate vaccine
PPD - delayed 4 to 6 weeks after MMR - - may interfere with the
tuberculin skin test
At what age is first MMR administered? Correct Answer-Administer
first dose at age 12 to 15 months
