NURS 5462 HEPATITIS EXAM QUESTIONS AND ANSWERS WITH
COMPLETE SOLUTIONS VERIFIED LATEST UPDATE
IgM Antibodies
early antigen immune response not lifetime immunity, clear in 6-18m
IgG
Lifetime immunity
Viral Hepatitis—A
- What can we measure? - IgM (acutely ill) and IgG antibodies (cleared dz >6m)
Viral Hepatitis—C
- Antibodies—but they are a measure of viral activity-have the virus—NOT immunity -
ELISA is screening method - Then Western Blot is confirmatory antibody test - Then if
both positive—the measure viral load, and genotype
Viral Hepatitis—E
- IgM and IgG antibodies (similar to hep a)
Viral Hepatitis—G
- Hepatitis G antigen, serum or stool
Viral Hepatitis—B
- What can we measure?
- Hepatitis B surface antigen
- Hepatitis B core antigen [non-detectable]**
- Hepatitis Be antigen
, - Hepatitis Be antibodies—IgM and IgG
- Hepatitis B core antibodies—IgM and IgG
- Hepatitis B surface antibodies—IgM and IgG
- **surrogate marker is Hepatitis B core antibody IgM (picture)
Viral Hepatitis—D
- Hepatitis B surface antigen IgM AND - Antibodies to Hepatitis D IgM and IgG
antibodies
no D S B
Viral Hepatitis: Acute Hepatitis
Fie types of viral hepatitis that are separate entities—A, B, C, E and G Hepatitis D [or ∆
Hepatitis] refers to a virus like particle depending on persistent or concomitant Hepatitis
B
Hepatitis A
Most common Spread by fecal-oral route and contaminated shell fish Most patients do
not develop jaundice Chronic hepatitis does not develop nor does a chronic carrier state
Most infectious during the prodromal symptoms
Diagnosis established by antibody to Hepatitis A
Hepatitis A: Serology
anti-HA IgM - acute/recent infection anti-HA IgG - prior infection - lifetime immunity
Hepatitis A RX
ETOH, OCP and other hepatotoxic drugs should be avoided Vaccine is available—
inactivated Hepatitis A virus given as 2 shots 6-12 months apart Immune globulin 0.02
ml/kg [effective o up to 2 weeks post exposure
COMPLETE SOLUTIONS VERIFIED LATEST UPDATE
IgM Antibodies
early antigen immune response not lifetime immunity, clear in 6-18m
IgG
Lifetime immunity
Viral Hepatitis—A
- What can we measure? - IgM (acutely ill) and IgG antibodies (cleared dz >6m)
Viral Hepatitis—C
- Antibodies—but they are a measure of viral activity-have the virus—NOT immunity -
ELISA is screening method - Then Western Blot is confirmatory antibody test - Then if
both positive—the measure viral load, and genotype
Viral Hepatitis—E
- IgM and IgG antibodies (similar to hep a)
Viral Hepatitis—G
- Hepatitis G antigen, serum or stool
Viral Hepatitis—B
- What can we measure?
- Hepatitis B surface antigen
- Hepatitis B core antigen [non-detectable]**
- Hepatitis Be antigen
, - Hepatitis Be antibodies—IgM and IgG
- Hepatitis B core antibodies—IgM and IgG
- Hepatitis B surface antibodies—IgM and IgG
- **surrogate marker is Hepatitis B core antibody IgM (picture)
Viral Hepatitis—D
- Hepatitis B surface antigen IgM AND - Antibodies to Hepatitis D IgM and IgG
antibodies
no D S B
Viral Hepatitis: Acute Hepatitis
Fie types of viral hepatitis that are separate entities—A, B, C, E and G Hepatitis D [or ∆
Hepatitis] refers to a virus like particle depending on persistent or concomitant Hepatitis
B
Hepatitis A
Most common Spread by fecal-oral route and contaminated shell fish Most patients do
not develop jaundice Chronic hepatitis does not develop nor does a chronic carrier state
Most infectious during the prodromal symptoms
Diagnosis established by antibody to Hepatitis A
Hepatitis A: Serology
anti-HA IgM - acute/recent infection anti-HA IgG - prior infection - lifetime immunity
Hepatitis A RX
ETOH, OCP and other hepatotoxic drugs should be avoided Vaccine is available—
inactivated Hepatitis A virus given as 2 shots 6-12 months apart Immune globulin 0.02
ml/kg [effective o up to 2 weeks post exposure
