NURS 5461 EXAM 1 EXAM QUESTIONS AND ANSWERS
WITH COMPLETE SOLUTIONS VERIFIED GRADED A++
Microcytic anemia
iron deficiency, usually due to malabsorption / occult blood loss, or lead poisoning. MCV
<80
Normocytic anemia
due to hemorrhage or chronic disease. Aplastic anemia. MVC 80-92
macrocytic anemia
due to folate or vitamin B12(cobalamin) deficiency (megaloblastic anemia) / pernicious
anemia. /liver diseases
serum ferritin
Tests for iron stores. As serum ferritin falls, TIBC rises, and serum iron levels will
eventually fall.
Anemia of chronic disease
NORMOcytic anemia with ↓ serum iron, ↓ TIBC, and normal iron stores. Treat with
epoetin and give an iron supplement
Schistocytes
Associated with hemolytic uremia syndrome
pernicious anemia
, Macrocytic anemia caused by vitamin B12 deficiency. B12 is essential to maturation of
erythrocytes - low levels will cause the RBC to expand. PPIs and histamine2 blockers
can cause this.
Increased homocysteine & methylmalonic acid level indicates ?
B12 deficiency
increased homocysteine levels
Folate deficiency
Sperocytes
Appear as spheres, lack central pallor, smaller diameter, indicate immune-mediated
process - can be seen after blood transfusion
aplastic anemia
a normocytic anemia characterized by the failure of bone marrow to produce red blood
cells
Low ferritin
iron deficiency anemia
Transferrin
transports iron
TIBC (total iron binding capacity)
Available transferrin that is left unbound (Represents the "empty seats on a train").
When iron is low, TIBC will be high. When iron is high, TIBC will be low
MCHC (mean corpuscular hemoglobin concentration)
WITH COMPLETE SOLUTIONS VERIFIED GRADED A++
Microcytic anemia
iron deficiency, usually due to malabsorption / occult blood loss, or lead poisoning. MCV
<80
Normocytic anemia
due to hemorrhage or chronic disease. Aplastic anemia. MVC 80-92
macrocytic anemia
due to folate or vitamin B12(cobalamin) deficiency (megaloblastic anemia) / pernicious
anemia. /liver diseases
serum ferritin
Tests for iron stores. As serum ferritin falls, TIBC rises, and serum iron levels will
eventually fall.
Anemia of chronic disease
NORMOcytic anemia with ↓ serum iron, ↓ TIBC, and normal iron stores. Treat with
epoetin and give an iron supplement
Schistocytes
Associated with hemolytic uremia syndrome
pernicious anemia
, Macrocytic anemia caused by vitamin B12 deficiency. B12 is essential to maturation of
erythrocytes - low levels will cause the RBC to expand. PPIs and histamine2 blockers
can cause this.
Increased homocysteine & methylmalonic acid level indicates ?
B12 deficiency
increased homocysteine levels
Folate deficiency
Sperocytes
Appear as spheres, lack central pallor, smaller diameter, indicate immune-mediated
process - can be seen after blood transfusion
aplastic anemia
a normocytic anemia characterized by the failure of bone marrow to produce red blood
cells
Low ferritin
iron deficiency anemia
Transferrin
transports iron
TIBC (total iron binding capacity)
Available transferrin that is left unbound (Represents the "empty seats on a train").
When iron is low, TIBC will be high. When iron is high, TIBC will be low
MCHC (mean corpuscular hemoglobin concentration)
