FINAL EXAM 300 QUESTIONS & ANSWERS / ADVANCED
PHARMACOLOGY FOR CARE OF FAMILY|ALREADY
GRADED A+
Raloxifene (Evista) and bisphosphonates (alendronate, calcitonin) - ANSWER:
alternatives for hormone replacement therapy
Selective Estrogen Receptor Modulators (SERMs) - ANSWER: Tamoxifen, toremifene,
raloxifene -- provide estrogen benefits while avoiding its drawbacks
Dysfunctional uterine bleeding - ANSWER: 10-14 day course of progestin
Amenorrhea treatment - ANSWER: progestin helps induce menstrual flow
Amenorrhea estrogen levels are low - ANSWER: give progestin for 5-10 days
Long term progestin therapy - ANSWER: protection against endometrial cancer
Estradiol - ANSWER: most active estrogenic compound. oral estrogen option
Advantages of estrogen transdermal patch - ANSWER: lower total estrogen dose. less
n/v. less fluctuation of estrogen blood levels. lower r/f DVT, PE and stroke
Femring - ANSWER: intravaginal ring controls hot flashes and night sweats. Treats
vulval and vaginal atrophy
No gap method of changing from one OC to another - ANSWER: go straight from one
type of OC to the other without taking a gap.
initiating OC treatment - ANSWER: first day of menstrual cycle (no backup BC
needed) OR first sunday after onset of menses (backup BC needed for 7 days)
Initiating androgen therapy short term - ANSWER: delayed sexual maturation causing
a boy significant distress. Limited course of Fluoxymesterone and
methyltestosterone are approved.
androgen therapy long term - ANSWER: if delayed puberty is the result of true
hypogonadism
role of androgens in anemia - ANSWER: promote synthesis of erythropoietin the
renal hormone that stimulates production of RBCs
Alprostadil preferred administration - ANSWER: direct injection into the corpus
cavernosum. Rapid response
, Finasteride - ANSWER: BPH tx 5a reductase inhibitor. Causes prostate to shrink.
benefits take months
Tamsulosin - ANSWER: BPH tx alpha adrenergic antagonist. relaxes smooth muscle.
benefits are rapid
Adverse effects of silodosin and tamsulosin - ANSWER: r/f floppy iris syndrome
during cataract surgery.
Chlamydia tx - ANSWER: azithromycin 1g PO x single dose. doxycycline 100mg PO
BID 7 days
Gonococcal urethritis tx - ANSWER: ceftriaxone IM single dose 250mg-1g based on
weight
Bacterial vaginosis tx - ANSWER: metronidazole 500mg PO 2x day for 7 days.
Herpes (HSV) tx - ANSWER: acyclovir 400mg TID 7-10 days, valacyclovir or famciclovir
Trichomoniasis tx - ANSWER: metronidazole 2g PO x1 dose or tinidazole
Syphilis - ANSWER: benzathine penicillin 2.4mil units IM
Mild symptoms PD tx - ANSWER: MAO-B inhibitor like rasagiline or selegiline
Severe symptoms PD tx - ANSWER: levodopa + carbodopa or dopamine agonist
PD tx for improving motor function - ANSWER: levodopa
PD tx for drug induced dyskinesias - ANSWER: dopamine agonist
COMT inhibitor - ANSWER: Entacapone (Comtan). added to levo/carbidopa to
increase levo concentrations & extend half life & decrease wearing off time
Pramipexole side effects - ANSWER: impulse control disorders, combined with
levodopa causes orthostatic hypotension and dyskinesias
Pregabalin - ANSWER: Safest medication for seizure patients on OC
Phenytoin - ANSWER: can decrease effects of OCs, warfarin and glucocorticoids
Migraine tx 1st line - ANSWER: serotonin 1b/1d receptor agonists (triptans)
First line migraine prevention - ANSWER: propanolol