41 Multiple choice questions
Term 1 of 41
what type of toxin is streptolysin O?
protein
proteins & polysaccharides
they are large complex molecules with lots of epitopes
exotoxin
(Gram + organisms)
extracellular hemolysin & cytolysin
A unit of measurement that expresses the levels of antibody titer.
Term 2 of 41
What is the principle of the neutralization test?
- Sheep/Human type "O" RBC's are used as an indication of neutralization of SLO
- If Ab's are present there will be no hemolysis
Cholesterol and related sterols
membrane cholesterol is the binding site of the toxin
measures ASO titers
2,800
non-antigenetic
-it is the size of a hapten
-must bind to another molecule (protein) to become antigenic
,Term 3 of 41
During a neutralization test, what happens if there is no AB to SLO?
Rbc's are enhanced and multiply rapidly
Ab binds to slo, preventing any effect
SLO is not neutralized and the RBC's are lysed
Slo is completely neutralized and no effect occurs
Term 4 of 41
what attribute gives streptolysin O its name?
it is oxygen labile
in the presence if O2 the molecule is oxidized and cannot lyse
proteins & polysaccharides
they are large complex molecules with lots of epitopes
necrosis of live and kidneys
massive hemolysis
injection into joints can cause chronic arthritis
strep throat
scarlet fever
rheumatic fever
acute glomerulonephritis
(life threatening)
, Term 5 of 41
What type of molecule is able to inhibit the action of SLO?
proteins & polysaccharides
they are large complex molecules with lots of epitopes
necrosis of live and kidneys
massive hemolysis
injection into joints can cause chronic arthritis
Cholesterol and related sterols
membrane cholesterol is the binding site of the toxin
exotoxin
(Gram + organisms)
extracellular hemolysin & cytolysin
Term 6 of 41
what type of molecule is streptolysin O
carbohydrate
protein
antibodies
lipid
Term 7 of 41
Where does SLO attach to a cell?
slo binds to the ribosomes of the cell
membrane cholesterol is the binding site of the toxin
the nucleus is the target for slo attachment
the cytoplasm is where slo is produced