MN553 Unit 8 Exam/Questions and
Answers A+ Graded with detailed
questions and correct answers
Benztropine
Oxybutynin
What is another term for anticonvulsants - CORRECT ANSWER Hydrations?
Examples of anticonvulsants - CORRECT ANSWER Ethotoin
Fosphenytoin
Phenytoin
Lamotrigine
Clinical uses for lamotrigine - CORRECT ANSWER Used in adjunctive treatment of
primary generalized tonic clonic seizures and partial seizures in adults and children
older than 2 years of age
,Concurrently used with valproic acid and phenytoin
Examples of nonselective norepinephrine serotonin reuptake inhibitors - CORRECT
ANSWERTCAs
Amitriptyline, nortriptyline, imipramine, doxepin, trimipramine maleate, amoxapine,
desipramine, protriptyline hydrochloride, clomipramine
Examples of MAOIs - CORRECT ANSWERPhelenzine, isocarboxazid, tranylcypromine
Examples of SSRIs - CORRECT ANSWERFluoxetine, olanzapine-fluoxetine,
paroxetine, sertraline, fluvoxamine, citalopram, escitralopram
Examples of serotonin -norepinephrine reuptake inhibitors (SNRIs) - CORRECT
ANSWERVenlafaxine (Effexor), duloxetine, (Cymbalta), milnacipran (Savella),
desvenlafaxine (Pristig)
Clinical use for TCAs - CORRECT ANSWERNocturnal enuresis
Intractable pain
Anxiety disorders.
Pharmacodynamics of TCAs - CORRECT ANSWERAct on neurotransmitters serotonin
and norepinephrine and histamine and acetylchoine
Pharmacokinetics of TCAs - CORRECT ANSWERFairly long half life of 6-18 hours
Liver metabolism strong CYP2D6
What should the treatment for depression always include - CORRECT ANSWER
Referral for psychological therapy
Treatment for pediatric depression - CORRECT ANSWERFluoxetine (Prozac)
Why are MAOIs avoided - CORRECT ANSWER Low safety margin
Not a first line drug
Many drug-drug, food- drug interactions
SSRI pharmacodynamics - CORRECT ANSWER Selective inhibitory effects on
presynaptic serotonin reuptake
SSRI pharmacokinetics - CORRECT ANSWERS low absorption
, Half-life 26 hours
Extensive first pass metabolism
Fluoxetine half-life - CORRECT ANSWER1-3 days
Fluoxetine first metabolite - CORRECT ANSWER4-16 days
SSRI ADRs - CORRECT ANSWERCNS
GI
Sexual dysfunction
Serotonin syndrome
SSRI patient education - CORRECT ANSWER Pregnancy Category B, C, or D
Withdrawal symptoms if abruptly discontinued
Avoid St. john’s worth
SSRI monitoring - CORRECT ANSWER Never give more than 4 weeks on first
prescription
Monitor target symptoms
SNRI clinical uses - CORRECT ANSWER Major depressive disorder
GAD
Neuropathy
Pain
Fibromyalgia
True or false
It is safe to use SNRIs in children - CORRECT ANSWERFalse
Not approved by the FDA for use in children
What drug class is considered atypical antidepressants - CORRECT ANSWERSNRIs
Answers A+ Graded with detailed
questions and correct answers
Benztropine
Oxybutynin
What is another term for anticonvulsants - CORRECT ANSWER Hydrations?
Examples of anticonvulsants - CORRECT ANSWER Ethotoin
Fosphenytoin
Phenytoin
Lamotrigine
Clinical uses for lamotrigine - CORRECT ANSWER Used in adjunctive treatment of
primary generalized tonic clonic seizures and partial seizures in adults and children
older than 2 years of age
,Concurrently used with valproic acid and phenytoin
Examples of nonselective norepinephrine serotonin reuptake inhibitors - CORRECT
ANSWERTCAs
Amitriptyline, nortriptyline, imipramine, doxepin, trimipramine maleate, amoxapine,
desipramine, protriptyline hydrochloride, clomipramine
Examples of MAOIs - CORRECT ANSWERPhelenzine, isocarboxazid, tranylcypromine
Examples of SSRIs - CORRECT ANSWERFluoxetine, olanzapine-fluoxetine,
paroxetine, sertraline, fluvoxamine, citalopram, escitralopram
Examples of serotonin -norepinephrine reuptake inhibitors (SNRIs) - CORRECT
ANSWERVenlafaxine (Effexor), duloxetine, (Cymbalta), milnacipran (Savella),
desvenlafaxine (Pristig)
Clinical use for TCAs - CORRECT ANSWERNocturnal enuresis
Intractable pain
Anxiety disorders.
Pharmacodynamics of TCAs - CORRECT ANSWERAct on neurotransmitters serotonin
and norepinephrine and histamine and acetylchoine
Pharmacokinetics of TCAs - CORRECT ANSWERFairly long half life of 6-18 hours
Liver metabolism strong CYP2D6
What should the treatment for depression always include - CORRECT ANSWER
Referral for psychological therapy
Treatment for pediatric depression - CORRECT ANSWERFluoxetine (Prozac)
Why are MAOIs avoided - CORRECT ANSWER Low safety margin
Not a first line drug
Many drug-drug, food- drug interactions
SSRI pharmacodynamics - CORRECT ANSWER Selective inhibitory effects on
presynaptic serotonin reuptake
SSRI pharmacokinetics - CORRECT ANSWERS low absorption
, Half-life 26 hours
Extensive first pass metabolism
Fluoxetine half-life - CORRECT ANSWER1-3 days
Fluoxetine first metabolite - CORRECT ANSWER4-16 days
SSRI ADRs - CORRECT ANSWERCNS
GI
Sexual dysfunction
Serotonin syndrome
SSRI patient education - CORRECT ANSWER Pregnancy Category B, C, or D
Withdrawal symptoms if abruptly discontinued
Avoid St. john’s worth
SSRI monitoring - CORRECT ANSWER Never give more than 4 weeks on first
prescription
Monitor target symptoms
SNRI clinical uses - CORRECT ANSWER Major depressive disorder
GAD
Neuropathy
Pain
Fibromyalgia
True or false
It is safe to use SNRIs in children - CORRECT ANSWERFalse
Not approved by the FDA for use in children
What drug class is considered atypical antidepressants - CORRECT ANSWERSNRIs
