NR507 MIDTERM EXAM REVISION
QUESTIONS AND CORRECT ANSWERS
Examples of hypersensitivity type 1
allergic rhinitis, anaphylactic reaction
Type 1 hypersensitivity reactions are mediated by
what
IgE
What cells are involved in hypersensitivity type 1
Mast cells
symptoms of hypersensitivity type 1
local: itching, immediate rash
systemic: wheezing
main treatment for anaphylaxis
epinephrine
Type 2 hypersensitivity is also known as what kind of
reaction?
cytoctoxic reaction, tissue specific
what cells are involved in type 2 hypersensitivity
reaction?
Macrophages
what does type 2 hypersensitivity do to tissues?
can cause damage or alter function of specific tissues
Examples of hypersensitivity type 2
graves disease/ hyperthyroidism, blood incompatibility
what is the difference between type 2 and 3
hypersensitivity?
, type 2 is organ specific; antibody binds to the antigen on
the surface of the cell
type 3 is NOT organ specific; binds outside of the cell
surface and is released into blood/ body fluids and then
deposited into tissues
examples of type 3 hypersensitivity
rheumatoid arthritis and lupus
autoimmune diseases can be...
genetic/familial
What is alloimmunity?
Immune reaction to tissues of another individual
Examples of alloimmunity
transplant rejection, transfusion reactions, Rh
incompatibility
what is hypersensitivity type 4
Delayed response, Occurs 24-72 hrs after exposure
doe not involve antigen/antibody complexes
Hypersensitivity type 4 is mediated by what?
T cells!!!
example of hypersensitivity type 4
contact dermatitis
poison ivy
delayed response occurs in area of contact
organ rejection is made up of what hypersensitivity
and why?
Type 2 and 4.
involves cytotoxicity (2)
T cells play a role in organ rejection (4)
atopic dermatitis is example of what
type 1 hypersensitivity
contact dermatitis is example of what
QUESTIONS AND CORRECT ANSWERS
Examples of hypersensitivity type 1
allergic rhinitis, anaphylactic reaction
Type 1 hypersensitivity reactions are mediated by
what
IgE
What cells are involved in hypersensitivity type 1
Mast cells
symptoms of hypersensitivity type 1
local: itching, immediate rash
systemic: wheezing
main treatment for anaphylaxis
epinephrine
Type 2 hypersensitivity is also known as what kind of
reaction?
cytoctoxic reaction, tissue specific
what cells are involved in type 2 hypersensitivity
reaction?
Macrophages
what does type 2 hypersensitivity do to tissues?
can cause damage or alter function of specific tissues
Examples of hypersensitivity type 2
graves disease/ hyperthyroidism, blood incompatibility
what is the difference between type 2 and 3
hypersensitivity?
, type 2 is organ specific; antibody binds to the antigen on
the surface of the cell
type 3 is NOT organ specific; binds outside of the cell
surface and is released into blood/ body fluids and then
deposited into tissues
examples of type 3 hypersensitivity
rheumatoid arthritis and lupus
autoimmune diseases can be...
genetic/familial
What is alloimmunity?
Immune reaction to tissues of another individual
Examples of alloimmunity
transplant rejection, transfusion reactions, Rh
incompatibility
what is hypersensitivity type 4
Delayed response, Occurs 24-72 hrs after exposure
doe not involve antigen/antibody complexes
Hypersensitivity type 4 is mediated by what?
T cells!!!
example of hypersensitivity type 4
contact dermatitis
poison ivy
delayed response occurs in area of contact
organ rejection is made up of what hypersensitivity
and why?
Type 2 and 4.
involves cytotoxicity (2)
T cells play a role in organ rejection (4)
atopic dermatitis is example of what
type 1 hypersensitivity
contact dermatitis is example of what
