ANSWERS COMPLETE AND RATED A.
1. A "first order process" is part of the process of: Elimination
2. Which of the following can affect bioavailability of a All of these factors
medication? can affect bioavail-
ability
3. An APRN is interested in researching how the body Pharmacokinetics
metabolizes and eliminates a particular drug. This is
also known as the study of:
4. Which drug administration and dosing regimen Continuous IV in-
would have the most consistent level of plasma con- fusion
centration?
5. What are two corrections needed for this prescrip- The dispense
tion? (Disp) line should
indicate that 30
tabs should be giv-
en and DAW is
incorrect; this line
should be used if
only the prescriber
does not want the
generic drug to be
dispensed
6. Pharmacokinetics involves four processes which de- Absorption, dis-
scribe what the body does to process drugs. They tribution, metabo-
are: lism and excretion
7. Most drugs are cleared from the body by: kidneys
8. 50%
, Assuming a first order process, half life is the amount
of time required for of a drug to be eliminated
from the body.
9. Percutaneous absorption (via skin) of medications is All of the answers
greater in newborns due to which of the following: are correct
10. Which of the following would be the correct format for Take one tablet by
the "Sig: " line on a prescription? mouth daily in the
morning
11. A 12-year-old patient is determined to have familial statins
hypercholesterolemia. Their LDL is 195 mg/dL and
their BMI is 27.5. Along with diet education and rec-
ommending increased physical activity, a treatment
plan for Jose would include
12. A patient has been diagnosed with hypertension and renal function
it is determined that an angiotensin-converting en-
zyme inhibitor is needed. Prior to prescribing this
drug, the advanced practice registered nurse (APRN)
should assess:
13. Patients with hyperlipidemia may be treated with HMG Co-A Re-
more than one drug. However, fibric acid derivatives, ductase inhibitors,
such as gemfibrozil should not be combined with: due to an in-
creased risk for
rhabdomyolysis
14. Jacob has hypertension, for which a dihydropyridine Decreases the
calcium channel blocker has been prescribed. This movement of cal-
drug helps control blood pressure because it: cium across the
cellular mem-
brane
15. Which of the following medications is considered lisinopril, an ACE
unsafe to use for treatment of hypertension during inhibitor
pregnancy?
16. Name two corrections needed for this prescription
, "sixty" should be
written out next to
"60" and a diag-
nosis code is re-
quired
17. In Ohio, if an APRN has a change in collaborating 30
physician, the APRN must notify the board of nursing
of that physician's name within how many days of the
change?
18. What is the role of the Ohio Committee on Prescrip- determine the ex-
tive Governance (CPG)? clusionary formu-
lary for APRN
practice
19. Which of the following is a written formal guide for Standard Care
planning and evaluating care by the APRN. Arrangement
20. Which category of medications for dyslipidemia can niacin
cause acanthosis nigricans as a side effect?
21. Furosemide is added to a treatment regimen for heart serum potassium
failure that includes digoxin. Monitoring for this com-
bination should prioritize the monitoring of
22. The advanced practice registered nurse (APRN) or- Amiodarone can
ders a blood test for thyroid function for a patient on damage the thy-
amiodarone. The patient tells the APRN that he does roid gland and can
not have thyroid disease and wants to know why the result in dysfunc-
test has been ordered. Which is a correct response? tion of the gland
23. What is the mechanism of action of nitroglycerin?