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NR507 FINAL EXAM REVISION SUMMARY ACCOMPANIED BY EXPECTED QUESTIONS AND THEIR CORRECT ANSWERS

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Generalized tonic-clonic seizures: -wide-spread and uncontrolled neuron activity in the entire cerebral cortex -occur in 10% of patients who have epilepsy -excessive neuronal discharge in the motor nerves through the brain. Generalized tonic seizures: this seizure is characterized by unconsciousness and muscle rigidity. Post-ictal phase (lasts one to two hours): characterized by confusion, unresponsiveness and muscle flaccidity. -Following the post-ictal state, there will be a return to normal state of consciousness Clonic phase (lasts one minute): continuous discharge of neurons gets interrupted. -characterized by small durations of relaxation, occur because of inhibitory mechanisms of the brain to try to control the wide-spread neuronal activity -patient will exhibit spasms and jerking, perceived as violent shaking of muscles. Generalized clonic seizures: this seizure is characterized by muscle spasms. Generalized absence seizure: -common in children -caused by a genetic abnormality -characterized by sudden and brief loss of consciousness without muscle tone -last for only a few seconds -no associated post-ictal confusion. Wide variety of options available, is based on needs of the patient Anticonvulsants Removes the cause of the seizure Surgery Ketogenic diet Produces energy other than glucose to be used by the brain Nerve stimulation Controls the seizure by influencing neurotransmitter release An individual having a focal seizure without dyscognitive features will _______ have no impairment of consciousness Febrile seizures most often ___________ medication as they ___________. do not need, resolve on their own. Tonic-clonic phase results in: 1. The muscles of the body become contracted. without any relaxation. 2. Loss of consciousness. 3. Ictal cry. This is a typical sound produced by the tonic contractions of the laryngeal muscles and muscles of expiration. 4. Respiratory impairment that results in cyanosis. 5. Tonic contraction of the jaw muscles that can cause tongue biting. 6. Increased sympathetic activity. This will cause increased heart rate and blood pressure Tonic-clonic phase lasts __________ 10-20 seconds Tonic-clonic phase is due to __________________ the excessive discharge of neurons in the motor nerves Underlying cause of BPH 5delta-reductace activity increases with age -increases dihydrotestosterone levels -normal prostate cells respond to the increase in dihydrotestosterone levels by living longer and multiplying acute kidney injury/acute renal failure sudden loss of kidney function Reversible S/S: -oliguria (30mL/hr) -increased BUN & creatinine -fluid & electrolyte abnormalities Prerenal Most common type of Acute Renal Failure Sudden & severe drop in BP (shock) or interruption of blood flow to the kidneys from severe injury or illness -causes: hypotension, decreased CO, decreased blood volume Intrarenal (intrinsic) Direct damage to the kidneys by inflammation, toxins, drugs, infection, or decreased blood supply. -Causes: acute tubular necrosis (ATN), acute glomerulonephritis, and other glomerulopathies Postrenal Sudden obstruction of urine flow due to enlarged prostate, kidney stones, bladder tumors, or injury. Prerenal labs -increased creatinine -increased BUN -increased BUN/creatinine ratio 20:1 -concentrated urine (high osmolarity) Intrinsic renal failure labs -increased creatining -increased BUN -BUN/creatinine ratio 15:1 -dilute urine Best way to differentiate between prerenal and intrinsic renal failure BUN/creatinine ratio Most common damage to the kidneys in intrinsic (intrinsic) renal disease is ___________ tubular (85%) others are: glomerular (5%) interstitial (8%) vascular (2%) Chronic Kidney Disease (CKD) Progressive loss of renal function that can develop as a complication of unresolved AKI or systemic diseases,

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NR507 FINAL EXAM REVISION
SUMMARY ACCOMPANIED BY
EXPECTED QUESTIONS AND THEIR
CORRECT ANSWERS


Generalized tonic-clonic seizures:
-wide-spread and uncontrolled neuron activity in the entire
cerebral cortex
-occur in 10% of patients who have epilepsy
-excessive neuronal discharge in the motor nerves
through the brain.
Generalized tonic seizures:
this seizure is characterized by unconsciousness and
muscle rigidity.
Post-ictal phase
(lasts one to two hours): characterized by confusion,
unresponsiveness and muscle flaccidity.
-Following the post-ictal state, there will be a return to
normal state of consciousness
Clonic phase
(lasts one minute): continuous discharge of neurons gets
interrupted.
-characterized by small durations of relaxation, occur
because of inhibitory mechanisms of the brain to try to
control the wide-spread neuronal activity
-patient will exhibit spasms and jerking, perceived as
violent shaking of muscles.

,Generalized clonic seizures:
this seizure is characterized by muscle spasms.
Generalized absence seizure:
-common in children
-caused by a genetic abnormality
-characterized by sudden and brief loss of consciousness
without muscle tone
-last for only a few seconds
-no associated post-ictal confusion.
Wide variety of options available, is based on needs of
the patient
Anticonvulsants
Removes the cause of the seizure
Surgery
Ketogenic diet
Produces energy other than glucose to be used by the
brain
Nerve stimulation
Controls the seizure by influencing neurotransmitter
release
An individual having a focal seizure without
dyscognitive features will _______
have no impairment of consciousness
Febrile seizures most often ___________ medication
as they ___________.
do not need, resolve on their own.
Tonic-clonic phase results in:
1. The muscles of the body become contracted. without
any relaxation.
2. Loss of consciousness.
3. Ictal cry. This is a typical sound produced by the tonic

, contractions of the laryngeal muscles and muscles of
expiration.
4. Respiratory impairment that results in cyanosis.
5. Tonic contraction of the jaw muscles that can cause
tongue biting.
6. Increased sympathetic activity. This will cause
increased heart rate and blood pressure
Tonic-clonic phase lasts __________
10-20 seconds
Tonic-clonic phase is due to __________________
the excessive discharge of neurons in the motor nerves
Underlying cause of BPH
5delta-reductace activity increases with age
-increases dihydrotestosterone levels
-normal prostate cells respond to the increase in
dihydrotestosterone levels by living longer and multiplying
acute kidney injury/acute renal failure
sudden loss of kidney function
Reversible
S/S:
-oliguria (<30mL/hr)
-increased BUN & creatinine
-fluid & electrolyte abnormalities
Prerenal
Most common type of Acute Renal Failure
Sudden & severe drop in BP (shock) or interruption of
blood flow to the kidneys from severe injury or illness
-causes: hypotension, decreased CO, decreased blood
volume
Intrarenal (intrinsic)

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