ANSWERS WITH COMPLETE SOLUTIONS VERIFIED
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Activation of B cells
Activation by antigen is aided by cytokine (secreted by helper T CD4+ )
Stimulated by antigen and cytokines, B Cells proliferate into memory and
effector/plasma cells (secrete antibodies)
Activation of T cells
CD8 surface marker protein attaches to MHC I (all nucleated cells); APCs, exogenous
antigen processing, peptide/MHC I complex on surface, binds to receptor/CD8; APC
releases activated T(C) cells; selcting a certain class of T(C) cells that can recognize a
foreign antigen
Primary versus Secondary
adaptive immunity
immunity or resistance to a specific pathogen; slower to respond, has memory
component
antibody
An antigen-binding immunoglobulin, produced by B cells, that functions as the effector
in an immune response.
, antigen binding site
The site on an immunoglobulin or T-cell receptor molecule that binds specific antigen.
antigen presentation
The process by which an MHC molecule binds to a fragment of an intracellular protein
antigen and carries it to the cell surface, where it is displayed and can be recognized by
a T cell.
Antigen-presenting cells (APCs)
cells such as B cells, macrophages, and dendritic cells that can present exogenous
antigens to naive or memory T cells, activating them
autoimmune disease
a condition in which the immune system mistakenly attacks itself, targeting the cells,
tissues, and organs of a person's own body
B cell receptor
The antigen receptor on B cells: a Y-Shaped, membrane-bound molecule consisting of
two identical heavy chains and two identical light chains linked by disulfide bridges and
containing two antigen-binding sites.
B lymphocytes (B cells)
produce antibodies
cell-mediated immunity
type of immunity produced by T cells that attack infected or abnormal body cells
CD4
Helper T cells
CD4+ Th1 cells