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Clinical Chemistry Exam 1 Study Guide
Solutions
Accuracy - ANSWER✔✔-The closeness with which a measurement comes to the true value
Precision - ANSWER✔✔-The degree of reproducibility in the measurement of a substance
Mean - ANSWER✔✔-Sum of all of a set divided by the number in the set (average)
Median - ANSWER✔✔-The point on the scale that has equal number of observations above and below
(even number, take the two-center numbers add and divide by 2)
Mode - ANSWER✔✔-The value in a set that occurs most frequently
Norm. Distribution - ANSWER✔✔-The theoretical bell-shaped curve based in the Gaussian Law of Errors.
Normal Frequency Curve
Standard Deviation - ANSWER✔✔-A statistical calculation that measures the scatter of sample values
around the mean. (The acceptable variation from the mean) The clinical lab uses 2 SD as an acceptable
variation in a method of analysis.
Confidence Limits - ANSWER✔✔-An expression of the amount of error that can be allowed in the
recovery of a value without affecting the validity
Coefficient of Variation - ANSWER✔✔-An expression of standard deviation as a percentage of the mean
A way of comparing the precision of different methods of assay
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, Copyright © OLIVIAWEST2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED
Also a better way to check the precision at various levels of concentration
Bias - ANSWER✔✔-A constant departure of quantity from the true value due to outside influence
Random Error - ANSWER✔✔-An error that does not occur in any regular predictable pattern
Systematic Error - ANSWER✔✔-A regularly occurring error that is constant, predictable, and traceable
Shift - ANSWER✔✔-Six to ten control values fall consecutively above or below the mean
Trend - ANSWER✔✔-An uninterrupted rise or decline away from the mean
Primary Standard - ANSWER✔✔-A solution generally containing a single purified solute in a pure solvent
The true value of the solvent is known by exact measurement (Analytical Balance) Used to "set" or
calibrate an instrument
Secondary Standard - ANSWER✔✔-A material with an established value(s) determined by assay against a
primary standard
It may contain one or more constituents
Control - ANSWER✔✔-Usually pooled human sera containing a number of substances used to verify the
precision of a method
Mole - ANSWER✔✔-Atomic Weight
Molarity - ANSWER✔✔-Atomic Weight/1 Liter (1000 mL)
Normality - ANSWER✔✔-N = Eq/L (1000mL)
Equivalent Weight - ANSWER✔✔-Equivalents =
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Clinical Chemistry Exam 1 Study Guide
Solutions
Accuracy - ANSWER✔✔-The closeness with which a measurement comes to the true value
Precision - ANSWER✔✔-The degree of reproducibility in the measurement of a substance
Mean - ANSWER✔✔-Sum of all of a set divided by the number in the set (average)
Median - ANSWER✔✔-The point on the scale that has equal number of observations above and below
(even number, take the two-center numbers add and divide by 2)
Mode - ANSWER✔✔-The value in a set that occurs most frequently
Norm. Distribution - ANSWER✔✔-The theoretical bell-shaped curve based in the Gaussian Law of Errors.
Normal Frequency Curve
Standard Deviation - ANSWER✔✔-A statistical calculation that measures the scatter of sample values
around the mean. (The acceptable variation from the mean) The clinical lab uses 2 SD as an acceptable
variation in a method of analysis.
Confidence Limits - ANSWER✔✔-An expression of the amount of error that can be allowed in the
recovery of a value without affecting the validity
Coefficient of Variation - ANSWER✔✔-An expression of standard deviation as a percentage of the mean
A way of comparing the precision of different methods of assay
Copyright ©Stuvia International BV 2010-2024 Page 1/6
, Copyright © OLIVIAWEST2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED
Also a better way to check the precision at various levels of concentration
Bias - ANSWER✔✔-A constant departure of quantity from the true value due to outside influence
Random Error - ANSWER✔✔-An error that does not occur in any regular predictable pattern
Systematic Error - ANSWER✔✔-A regularly occurring error that is constant, predictable, and traceable
Shift - ANSWER✔✔-Six to ten control values fall consecutively above or below the mean
Trend - ANSWER✔✔-An uninterrupted rise or decline away from the mean
Primary Standard - ANSWER✔✔-A solution generally containing a single purified solute in a pure solvent
The true value of the solvent is known by exact measurement (Analytical Balance) Used to "set" or
calibrate an instrument
Secondary Standard - ANSWER✔✔-A material with an established value(s) determined by assay against a
primary standard
It may contain one or more constituents
Control - ANSWER✔✔-Usually pooled human sera containing a number of substances used to verify the
precision of a method
Mole - ANSWER✔✔-Atomic Weight
Molarity - ANSWER✔✔-Atomic Weight/1 Liter (1000 mL)
Normality - ANSWER✔✔-N = Eq/L (1000mL)
Equivalent Weight - ANSWER✔✔-Equivalents =
Copyright ©Stuvia International BV 2010-2024 Page 2/6
