PANCE - HEMATOLOGY ONCOLOGY EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS VERIFIED

PANCE - HEMATOLOGY ONCOLOGY EXAM QUESTIONS AND

ANSWERS WITH COMPLETE SOLUTIONS VERIFIED


Heparin

Increases PTT

Affects Intrinsic pathway

Protamine Sulfate

Antidote for Heparin

Warfarin

Increases PT

Inhibits vitamin K

Affects Extrinsic pathway

Vitamin K

Antidote for Warfarin

aPTT

Bleeding lab prolonged in Hemophilia

A, VII

Hemophilia ___ or Factor ___ deficiency

X linked inheritance

Most common severe congenital clotting deficiency (90%)

B, IX

, Hemophilia __ or Factor __ deficiency

X linked inheritance

9% prevalence

C, XI

Hemophilia __ or Factor __ deficiency

Most common in Ashkenazi Jews

<1% prevalence

VII

Factor ___ deficiency

Presents in a molder, likely heterozygous form

<1% prevalence

Clotting factors

Treat bleeding episodes of hemophilia with transfusion of ____ ____

Desmopressin (DDAVP)

Mild hemophilia may be treated with ____

This helps the body to release extra Factor VIII

Von Willebrand's Factor

Autosomal dominant

Also has low levels of Factor VIII

Most common inherited bleeding disorder

aPTT

Prolonged ______ is seen in VWF

VWF