what are some common drugs that can induce kidney disease? - (answer)Aminoglycosides, Amphotericin
B, Cisplatin, NSAIDS, loop diuretics, cyclosporin, vanco, radio contrast dye, tacrolimus
What are some patient factors that limits the cockcroft gault equation? - (answer)very low or high
muscle mass, obese, liver damage, pregnant,
what is the blood pressure goals according to KDIGO? - (answer)140/90 in patients with no proteinuria,
130/80 if proteinuria is present
what is the mechanism of developing anemia in patients with CKD? - (answer)erythropoietin is produced
in the kidneys, which stimulate formation of reticulocytes (immature RBC) as kidney function declines so
does EPO production
What is the preferred route of Iron administration in patients undergoing hemodialysis? - (answer)IV
what is the mechanism for bone disorders in people with CKD? - (answer)initially phosphorus cannot be
excreted leading to hyper phosphotemia, the body responds by producing more PTH, this causes
increased rate of bone turnover
when should phosphate binders be administered? - (answer)with a meal
what is the problem with aluminum based phosphate binders? - (answer)they can accumulate and are
toxic to the nervous system
How do you treat elevations in PTH? - (answer)with vitamin D
Is potassium an intracellular or extracellular ion? - (answer)intracellular
why is excessive intake of potassium not usually associated with hyperkalemia? - (answer)because
insulin will drive the K into cells. Only if the kidney is severely damaged will this be an issue.