BIOCHEM BRS BOOK- PRINCIPLES 2 TEST 2 EXAM
QUESTIONS AND ANSWERS
9. A 4-month-old infant presents with a seizure. His mother reports that her infant
has been irri- table and lethargic over the past several days. The infant is found to
be profoundly hypoglyce- mic and have low ketones. Short-chain dicar- boxylic
acids are found to be elevated in the serum. The most likely enzyme deficiency is
which of the following?
A) Medium-chain acyl CoA dehydrogenase (MCAD)
B) Carnitine acyltransferase I
C) Hormone-sensitive lipase
D) Pyruvate carboxylase Fatty acyl CoA synthetase
A. MCAD
7. A 36-year-old woman is training for her first marathon, and her coach has her
keeping a pace that allows her to stay below her anaerobic threshold. By avoiding
anaerobic muscle glycol-ysis, the pyruvate produced in the muscle does not
accumulate because it is converted to which one of the following?
a. ethanol
b. lactic acid
c. Acetyl CoA
, d. Alanine
e. OAA
C. Acetyl CoA
3. In which one of the following scenarios would one expect to observe an
increase in liver fructose 2,6-bisphosphate levels?
(A) After the release of epinephrine
(B) In an individual who had just finished run-
ning a marathon
(C) In a patient exhibiting diabetic ketoacidosis
(D) After the consumption of a large bowl of ice
cream
(E) In a patient with kwashiorkor
D. after consumption of a large bowl of ice cream
2. A 47-year-old obese man complains of having to get out of bed three times a
night to urinate (polyuria), being constantly thirsty (polydipsia), and eating more
often (polypha- gia). The patient is diagnosed with insulin- resistant diabetes
mellitus (type 2). If the patient's symptoms are due to a problem at the level of the
glucose transporter, which one of the tissues indicated below will be most
affected?
a. RBCs
b. Small intestines
c. Muscle
QUESTIONS AND ANSWERS
9. A 4-month-old infant presents with a seizure. His mother reports that her infant
has been irri- table and lethargic over the past several days. The infant is found to
be profoundly hypoglyce- mic and have low ketones. Short-chain dicar- boxylic
acids are found to be elevated in the serum. The most likely enzyme deficiency is
which of the following?
A) Medium-chain acyl CoA dehydrogenase (MCAD)
B) Carnitine acyltransferase I
C) Hormone-sensitive lipase
D) Pyruvate carboxylase Fatty acyl CoA synthetase
A. MCAD
7. A 36-year-old woman is training for her first marathon, and her coach has her
keeping a pace that allows her to stay below her anaerobic threshold. By avoiding
anaerobic muscle glycol-ysis, the pyruvate produced in the muscle does not
accumulate because it is converted to which one of the following?
a. ethanol
b. lactic acid
c. Acetyl CoA
, d. Alanine
e. OAA
C. Acetyl CoA
3. In which one of the following scenarios would one expect to observe an
increase in liver fructose 2,6-bisphosphate levels?
(A) After the release of epinephrine
(B) In an individual who had just finished run-
ning a marathon
(C) In a patient exhibiting diabetic ketoacidosis
(D) After the consumption of a large bowl of ice
cream
(E) In a patient with kwashiorkor
D. after consumption of a large bowl of ice cream
2. A 47-year-old obese man complains of having to get out of bed three times a
night to urinate (polyuria), being constantly thirsty (polydipsia), and eating more
often (polypha- gia). The patient is diagnosed with insulin- resistant diabetes
mellitus (type 2). If the patient's symptoms are due to a problem at the level of the
glucose transporter, which one of the tissues indicated below will be most
affected?
a. RBCs
b. Small intestines
c. Muscle
