MLT 106 TEST 3 ABO AND RH BLOOD
SYSTEM GROUPS QUESTIONS WITH
100% CORRECT ANSWERS [ GRADED A+]
The ABO system was discovered in 1901 by _____ - ✔✔Karl Landsteiner
Almost all healthy people older than ____ of age have _______ to the
ABO antigens they lack - ✔✔3-6 months; naturally occurring antibodies
Landsteiner demonstrated that a person's serum contained
antibodies(naturally occurring) against ______ - ✔✔an antigen absent
from his own red blood cells; also termed *isohemagglutinins*
"Landsteiner's Rule" states:
If the ABO *antigen is present on the cells,* ______
,If the ABO *antibody is present in the serum,* ______ - ✔✔- the
corresponding *antibody will be absent from the serum*
- the corresponding *antigen will be absent on the cells*
The ABO blood group system remains the most important in ______
and ____ practice. - ✔✔Transfusion and transplantation
An *incompatible ABO transfusion* results to _______ - ✔✔acute
intravascular hemolysis and renal failure , and can be fatal
Today, ABO typing reagents are manufactured from _____ derived from
culture cell lines, which have several advantages over conventional
human and plant ABO reagents. - ✔✔monoclonal antibodies;
- Major advantages is *reproducibility*
; undesired antibody specificities are also excluded from the antisera
Anti-A reagent is - ✔✔Blue
Anti-B reagent is - ✔✔Yellow
,There is always an ________ between the *forward and reverse type;*
thus, one serves as a check on the other. - ✔✔inverse reciprocal
relationship
Phenotype *A* - ✔✔*Forward typing*
+,=
*Reverse typing*
=, +
Phenotype *B* - ✔✔*Forward typing*
=, +
*Reverse typing*
+, =
Phenotype *AB* - ✔✔*Forward typing*
+, +
*Reverse typing*
, =, =
Phenotype *O* - ✔✔*Forward typing*
=, =
*Reverse typing*
+, +
Forward Grouping (also known as front type): - ✔✔Testing for an
individual's ABO antigens( unknown antigens on the red blood cells)
using antisera (reagents with known ABO antibodies)
; Anti-A
; Anti-B
Reverse Grouping (also known as back type) - ✔✔Testing for the
presence or absence of individual ABO antibodies(unknown antibodies)
using reagent red blood cells(known antigens)
; 2 to 4% suspension of Reagent A1 Cells
SYSTEM GROUPS QUESTIONS WITH
100% CORRECT ANSWERS [ GRADED A+]
The ABO system was discovered in 1901 by _____ - ✔✔Karl Landsteiner
Almost all healthy people older than ____ of age have _______ to the
ABO antigens they lack - ✔✔3-6 months; naturally occurring antibodies
Landsteiner demonstrated that a person's serum contained
antibodies(naturally occurring) against ______ - ✔✔an antigen absent
from his own red blood cells; also termed *isohemagglutinins*
"Landsteiner's Rule" states:
If the ABO *antigen is present on the cells,* ______
,If the ABO *antibody is present in the serum,* ______ - ✔✔- the
corresponding *antibody will be absent from the serum*
- the corresponding *antigen will be absent on the cells*
The ABO blood group system remains the most important in ______
and ____ practice. - ✔✔Transfusion and transplantation
An *incompatible ABO transfusion* results to _______ - ✔✔acute
intravascular hemolysis and renal failure , and can be fatal
Today, ABO typing reagents are manufactured from _____ derived from
culture cell lines, which have several advantages over conventional
human and plant ABO reagents. - ✔✔monoclonal antibodies;
- Major advantages is *reproducibility*
; undesired antibody specificities are also excluded from the antisera
Anti-A reagent is - ✔✔Blue
Anti-B reagent is - ✔✔Yellow
,There is always an ________ between the *forward and reverse type;*
thus, one serves as a check on the other. - ✔✔inverse reciprocal
relationship
Phenotype *A* - ✔✔*Forward typing*
+,=
*Reverse typing*
=, +
Phenotype *B* - ✔✔*Forward typing*
=, +
*Reverse typing*
+, =
Phenotype *AB* - ✔✔*Forward typing*
+, +
*Reverse typing*
, =, =
Phenotype *O* - ✔✔*Forward typing*
=, =
*Reverse typing*
+, +
Forward Grouping (also known as front type): - ✔✔Testing for an
individual's ABO antigens( unknown antigens on the red blood cells)
using antisera (reagents with known ABO antibodies)
; Anti-A
; Anti-B
Reverse Grouping (also known as back type) - ✔✔Testing for the
presence or absence of individual ABO antibodies(unknown antibodies)
using reagent red blood cells(known antigens)
; 2 to 4% suspension of Reagent A1 Cells
