MCB 450 exam questions with complete
solutions 2024
Formation jof jthe jlinkages jthat jjoin jthe jamino jacids jin ja jpolypeptides jinvolves:
j- jANS✓✓-Elimination jof jone jwater jmolecule jper jlinkage jformed
Which jof jthe jfollowing jmolecules jare jthe jmajor jcomponents jof jthe jmembrane?
j- jANS✓✓-Lipids
Glycosidic jbond jis ja jtype jof jcovalent jbond jthat jcould jbe jcarried jout jby jwhich
jof jthe jfollowing jenzymes? j- jANS✓✓-glycogen jsynthase
Which jof jthe jfollowing jis jconsidered ja jnoncovalent jbond? j- jANS✓✓-Hydrogen
jbonds
van jder jWaals jinteractions
Electrostatic jinteractions
All jof jthe jabove.
What jis jthe j[A-]/[HA] jratio jwhen jthe jweak jacid jis jin ja jsolution jtwo jpH junits
jabove jits jpKa? j- jANS✓✓-100:1
What jhappens jto jnonpolar jmolecules jin jwater? j- jANS✓✓-They jaggregate
jtogether
Consider ja jbiochemical jreaction jthat jis jtaking jplace jin ja j0.1 jM jbuffer. jThe
jinitial jpH jis j7.4, jand jthe jpKa jof jthe jbuffer jis j7.2. jIf, jin ja jfinal jreaction jvolume jof
j1.0 jmL, j10 jmicromol jof jprotons jare jgenerated, jwhat jwould jbe jthe jfinal jpH jof
jthe jsolution? j- jANS✓✓-7.22
,Which jone jof jthe jfollowing jstatements jconcerning jthe jpeptide jshown jbelow jis
jcorrect? jGly-Cys-Giu-Ser-Asp-Arg-Cys j- jANS✓✓-The jpeptide jis jable jto jform jan
jinternal jdisulfide jbond
The jletters jA jthrough jE jdesignate jcertain jregions jon jthe jtitration jcurve jfor
jglycine j(shown jbelow) j. jWhich jone jof jthe jfollowing jstatements jconcerning jthis
jcurve jis jcorrect? j- jANS✓✓-Point jC jrepresents jthe jregion jwhere jthe jnet jcharge
jon jglycine jis jzero.
Which jof jthe jfollowing jcharacterize jαlpha-helix jregions jof jproteins? j- jANS✓✓-
They jare jformed jprincipally jby jhydrogen jbonds jbetween ja jcarbonyl joxygen
jatom jin jone jpeptide jbond jand jthe jamide jhydrogen jfrom ja jdifferent jpeptide
jbond j4 jamino jacids japart.
Autopsies jof jpatients jwith jAlzheimer jdisease jshow jprotein jaggregates jcalled
jneurofibrillary jtangles jand jneuritic jplaques jin jvarious jregions jof jthe jbrain.
jThese jplaques jexhibit jthe jcharacteristic jstaining jof jamyloid. jWhich jof jthe
jfollowing jstructural jfeatures jis jthe jmost jlikely jcharacteristic jof jat jleast jone
jprotein jin jthese jplaques? j- jANS✓✓-A jhigh jcontent jof jβ-pleated jsheet jstructure
A jprotein jhas jone jtransmembrane jdomain jcomposed jentirely jof ja-helical
jsecondary jstructure. jWhich jof jthe jfollowing jamino jacids jwould jyou jexpect jto
jfind jin jthe jtransmembrane jdomain? j- jANS✓✓-Leucine
Why jis jthe jpeptide jbond jplanar? j- jANS✓✓-It jexhibits jpartial jdouble-bond
jcharacter, jpreventing jrotation.
Your jstudy jgroup jis jtrying jto jidentify jdifferences jin jthe jfour jlevels jof jprotein
jstructure. jWhich jof jthe jfollowing jwould jyou jsay jis jtrue jof jimportant jstabilizing
jforces jin jsecondary jstructure jbut jnot jtertiary jstructure? j- jANS✓✓-The
jstructure jis jstabilized jby jH-bonding jbetween jthe joxygen jof jthe jbackbone
jcarbonyl jand jthe jhydrogen jof jthe jbackbone jamine.
All jof jthe jfollowing jwould jdisrupt jquaternary jstructure jexcept: j- jANS✓✓-Treat
jwith jascorbic jacid j(vitamin jC).
, Digestion jis___________ j- jANS✓✓-the jprocess jof jbreaking jdown jlarge
jmolecules jin jfood.
The jpancreas jreleases j_________ jto jbuffer jthe jpH jof jthe jstomach jjuices. j-
jANS✓✓-NaHCO3
Pepsin jrequires j_________ jto jachieve jactivity j- jANS✓✓-Partial jdenaturation jof
jprotein
Zymogen jactivation
Low jpH
Correct: jAll jof jthe jabove
The jresult jof jlipase jactivity jin jdigestion jis: j- jANS✓✓-Monoacylgycerol jand jtwo
jfree jfatty jacids.
Which jone jof jthe jfollowing jstatements jabout jthe jdigestion jof jlipids jis jcorrect?
j- jANS✓✓-Patients jwith jcystic jfibrosis jhave jdifficulties jwith jdigestion jbecause
jtheir jthickened jpancreatic jsecretions jare jless jable jto jreach jthe jsmall jintestine,
jthe jprimary jsite jof jlipid jdigestion.
Which jone jof jthe jfollowing jstatements jabout jthe jabsorption jof jlipids jfrom jthe
jintestine jis jcorrect? j- jANS✓✓-The jTAG jcarried jby jchylomicrons jis jdegraded jto
jfree jfatty jacids jand jglycerol jby jlipoprotein jlipase jon jthe jendothelial jsurface jof
jcapillaries jin jmuscle jand jadipose jprimarily.
A jyoung jblack jman jentered jhis jphysician's joffice jcomplaining jof jbloating jand
jdiarrhea. jHis jeyes jwere jsunken jand jthe jphysician jnoted jadditional jsigns jof
jdehydration. jThe jpatient's jtemperature jwas jnormal. jHe jexplained jthat jthe
jepisode jhad joccurred jfollowing ja jbirthday jparty jat jwhich jhe jhad jparticipated
jin jan jice jcream jeating jcontest. jThe jpatient jreported jprior jepisodes jof ja jsimilar
jnature jfollowing jingestion jof ja jsignificant jamount jof jdairy jproducts. jThis
jclinical jpicture jis jmost jprobably jdue jto ja jdeficiency jin: j- jANS✓✓-lactase
The jtransport jof jlipids jin jthe jlymph jis jcarried jout jby: j- jANS✓✓-chylomicrons
During jthe jdegradation jof jmany jamino jacids, jthe jfirst jstep jinvolves jtransfer jof
jthe jamino jgroup jto jwhich jcitric jacid jcycle jintermediate? j- jANS✓✓-α-
ketoglutarate
solutions 2024
Formation jof jthe jlinkages jthat jjoin jthe jamino jacids jin ja jpolypeptides jinvolves:
j- jANS✓✓-Elimination jof jone jwater jmolecule jper jlinkage jformed
Which jof jthe jfollowing jmolecules jare jthe jmajor jcomponents jof jthe jmembrane?
j- jANS✓✓-Lipids
Glycosidic jbond jis ja jtype jof jcovalent jbond jthat jcould jbe jcarried jout jby jwhich
jof jthe jfollowing jenzymes? j- jANS✓✓-glycogen jsynthase
Which jof jthe jfollowing jis jconsidered ja jnoncovalent jbond? j- jANS✓✓-Hydrogen
jbonds
van jder jWaals jinteractions
Electrostatic jinteractions
All jof jthe jabove.
What jis jthe j[A-]/[HA] jratio jwhen jthe jweak jacid jis jin ja jsolution jtwo jpH junits
jabove jits jpKa? j- jANS✓✓-100:1
What jhappens jto jnonpolar jmolecules jin jwater? j- jANS✓✓-They jaggregate
jtogether
Consider ja jbiochemical jreaction jthat jis jtaking jplace jin ja j0.1 jM jbuffer. jThe
jinitial jpH jis j7.4, jand jthe jpKa jof jthe jbuffer jis j7.2. jIf, jin ja jfinal jreaction jvolume jof
j1.0 jmL, j10 jmicromol jof jprotons jare jgenerated, jwhat jwould jbe jthe jfinal jpH jof
jthe jsolution? j- jANS✓✓-7.22
,Which jone jof jthe jfollowing jstatements jconcerning jthe jpeptide jshown jbelow jis
jcorrect? jGly-Cys-Giu-Ser-Asp-Arg-Cys j- jANS✓✓-The jpeptide jis jable jto jform jan
jinternal jdisulfide jbond
The jletters jA jthrough jE jdesignate jcertain jregions jon jthe jtitration jcurve jfor
jglycine j(shown jbelow) j. jWhich jone jof jthe jfollowing jstatements jconcerning jthis
jcurve jis jcorrect? j- jANS✓✓-Point jC jrepresents jthe jregion jwhere jthe jnet jcharge
jon jglycine jis jzero.
Which jof jthe jfollowing jcharacterize jαlpha-helix jregions jof jproteins? j- jANS✓✓-
They jare jformed jprincipally jby jhydrogen jbonds jbetween ja jcarbonyl joxygen
jatom jin jone jpeptide jbond jand jthe jamide jhydrogen jfrom ja jdifferent jpeptide
jbond j4 jamino jacids japart.
Autopsies jof jpatients jwith jAlzheimer jdisease jshow jprotein jaggregates jcalled
jneurofibrillary jtangles jand jneuritic jplaques jin jvarious jregions jof jthe jbrain.
jThese jplaques jexhibit jthe jcharacteristic jstaining jof jamyloid. jWhich jof jthe
jfollowing jstructural jfeatures jis jthe jmost jlikely jcharacteristic jof jat jleast jone
jprotein jin jthese jplaques? j- jANS✓✓-A jhigh jcontent jof jβ-pleated jsheet jstructure
A jprotein jhas jone jtransmembrane jdomain jcomposed jentirely jof ja-helical
jsecondary jstructure. jWhich jof jthe jfollowing jamino jacids jwould jyou jexpect jto
jfind jin jthe jtransmembrane jdomain? j- jANS✓✓-Leucine
Why jis jthe jpeptide jbond jplanar? j- jANS✓✓-It jexhibits jpartial jdouble-bond
jcharacter, jpreventing jrotation.
Your jstudy jgroup jis jtrying jto jidentify jdifferences jin jthe jfour jlevels jof jprotein
jstructure. jWhich jof jthe jfollowing jwould jyou jsay jis jtrue jof jimportant jstabilizing
jforces jin jsecondary jstructure jbut jnot jtertiary jstructure? j- jANS✓✓-The
jstructure jis jstabilized jby jH-bonding jbetween jthe joxygen jof jthe jbackbone
jcarbonyl jand jthe jhydrogen jof jthe jbackbone jamine.
All jof jthe jfollowing jwould jdisrupt jquaternary jstructure jexcept: j- jANS✓✓-Treat
jwith jascorbic jacid j(vitamin jC).
, Digestion jis___________ j- jANS✓✓-the jprocess jof jbreaking jdown jlarge
jmolecules jin jfood.
The jpancreas jreleases j_________ jto jbuffer jthe jpH jof jthe jstomach jjuices. j-
jANS✓✓-NaHCO3
Pepsin jrequires j_________ jto jachieve jactivity j- jANS✓✓-Partial jdenaturation jof
jprotein
Zymogen jactivation
Low jpH
Correct: jAll jof jthe jabove
The jresult jof jlipase jactivity jin jdigestion jis: j- jANS✓✓-Monoacylgycerol jand jtwo
jfree jfatty jacids.
Which jone jof jthe jfollowing jstatements jabout jthe jdigestion jof jlipids jis jcorrect?
j- jANS✓✓-Patients jwith jcystic jfibrosis jhave jdifficulties jwith jdigestion jbecause
jtheir jthickened jpancreatic jsecretions jare jless jable jto jreach jthe jsmall jintestine,
jthe jprimary jsite jof jlipid jdigestion.
Which jone jof jthe jfollowing jstatements jabout jthe jabsorption jof jlipids jfrom jthe
jintestine jis jcorrect? j- jANS✓✓-The jTAG jcarried jby jchylomicrons jis jdegraded jto
jfree jfatty jacids jand jglycerol jby jlipoprotein jlipase jon jthe jendothelial jsurface jof
jcapillaries jin jmuscle jand jadipose jprimarily.
A jyoung jblack jman jentered jhis jphysician's joffice jcomplaining jof jbloating jand
jdiarrhea. jHis jeyes jwere jsunken jand jthe jphysician jnoted jadditional jsigns jof
jdehydration. jThe jpatient's jtemperature jwas jnormal. jHe jexplained jthat jthe
jepisode jhad joccurred jfollowing ja jbirthday jparty jat jwhich jhe jhad jparticipated
jin jan jice jcream jeating jcontest. jThe jpatient jreported jprior jepisodes jof ja jsimilar
jnature jfollowing jingestion jof ja jsignificant jamount jof jdairy jproducts. jThis
jclinical jpicture jis jmost jprobably jdue jto ja jdeficiency jin: j- jANS✓✓-lactase
The jtransport jof jlipids jin jthe jlymph jis jcarried jout jby: j- jANS✓✓-chylomicrons
During jthe jdegradation jof jmany jamino jacids, jthe jfirst jstep jinvolves jtransfer jof
jthe jamino jgroup jto jwhich jcitric jacid jcycle jintermediate? j- jANS✓✓-α-
ketoglutarate
