MCB 450 Exam 1 questions with
complete solutions 2024
Which jof jthe jfollowing jamino jacids jhas ja jrelatively juncharged jside jchain junder
jphysiological jconditions:
a. jArginine
b. jAspartate
c. jGlutamate
d. jLysine
e. jHistidine j- jANS✓✓-E
Which jof jthe jfollowing jbest jdescribes jtheir jarrangement jof jamino jacid jside
jchains jin jan jalpha jhelix:
a. jThe jside jchains jpoint joutward jaway jfrom jthe jhelical jaxis
b. jThe jside jchains jpoint jinward jtoward jthe jcenter jof jthe jhelix
c. jThe jside jchains jpoint jtoward jthe jN-terminal jend jof jthe jhelix
d. jThe jside jchains jpoint jtoward jthe jC-terminal jend jof jthe jhelix
e. jThe jside jchains jpoint jtoward jthe jnearest jbeta jsheet j- jANS✓✓-A
Which jof jthe jfollowing jsecondary jstructures jis jmost jlikely jto jbe jfound jin ja
jmembrane-embedded jportion jof ja jprotein:
a. jAn jalpha jhelix jcomposed jentirely jof jhydrophobic jresidues
b. jAn jalpha jhelical jcoiled jcoil
c. jA jsingle jextended jbeta jstrand
d. jAn jopen jparallel jbeta jsheet jcomposed jof jhydrophobic jresidues
e. jAn jopen jparallel jbeta jsheet jcomposed jof jhydrophilic jresidues j- jANS✓✓-A
Which jof jthe jfollowing jis jnecessarily jcharacterized jby ja jcovalent jlinkage:
a. jBase-pairing jinteraction
b. jDisulfide jbond
c. jHydrogen jbond
d. jInduced jfit
e. jVan jder jWaals jinteraction j- jANS✓✓-B
,Enzymes jthat jare jactivated jby jspecific jproteolytic jcleavage jare jcalled:
a. jIsozymes
b. jZymogens
c. jAllosteric
d. jHeterozymes
e. jNuclease j- jANS✓✓-B
Denature jof jproteins jby jgastric jacids jis jdue jto jthe jdisruption jof j_________ jby
jlow jpH:
a. jPeptide jbonds
b. jDisulfide jbonds
c. jIonic jbonds jand jhydrogen jbonds
d. jHydrophobic jinteractions
e. jEster jbonds j- jANS✓✓-C
Deficiency jof jwhich jof jthe jfollowing jenzyme jleads jto jthe jlactose jintolerance?:
a. jMaltase
b. jLactase
c. jSucrase
d. jAlpha-amylase
e. jAlpha-glucosidase j- jANS✓✓-B
________ jare jmolecules jthat jaid jin jlipid jabsorption. jThey jare jsynthesized jfrom
jcholesterol jin jthe jliver jand jsecreted jfrom jthe j________.:
a. jBile jsalts; jpancreas
b. jBile jsalts; jgall jbladder
c. jBile jsalts; jintestine
d. jLipases; jpancreas
e. jCholesterol jesterase; jgall jbladder j- jANS✓✓-B
What jis jthe jfunction jof jApoCII jin jthe jchylomicrons?:
a. jIt jis jrecognized jby jhepatic jreceptors jfor jrecycling
b. jIt jis jthe jstructure jprotein jfor jthe jformation jof jchylomicrons
c. jIt jis jrequired jfor jthe jtransportation jof jchylomicrons jin jthe jblood
d. jIt jis jnecessary jfor jthe jactivation jof jlipoprotein jlipase
e. jIt jis jinvolved jin jthe jre-synthesis jof jTAG jin jthe jsmall jintestine j- jANS✓✓-D
Which jof jthe jfollowing janswers jcompletes jthe jsentence jcorrectly? jCytosine jis
ja?
a. jPurine jbase
b. jPurine jnucleoside
, c. jPyrimidine jbase
d. jPyrimidine jnucleoside j- jANS✓✓-C
During jthe jsynthesis jof jpyrimidine jnucleotides, jthe jpyrimidine jring jframework
jthat jbecomes jattached jto jthe jribose jis?
a. jUracil
b. jOrotate
c. jCytosine
d. jAdenine j- jANS✓✓-B
Which jone jof jthe jfollowing jenzymes jof jnucleotide jmetabolism jis jcorrectly
jpaired jwith jits jpharmacological jinhibitor?
a. jDihydrofolate jreductase- j- j-methotrexate
b. jIMP jdehydrogenase- j- j-hydroxyurea
c. jRibonucleotide jreductase- j- j-5-fluorouracil
d. jThymidylate jsynthase- j- j-allopurinol
e. jXanthine joxidase- j- j-probencid j- jANS✓✓-A
What jis jthe jbiochemical jdeficiency jthat jleads jto jsevere jcombined
jimmunodeficiency jdisease j(SCID)?
a. jNucleoside jphosphorylase
b. jXanthine joxidase
c. jAdenosine jdeaminase
d. jAll jof jthe jabove j- jANS✓✓-C
Which jof jthe jfollowing jchemicals jcan jbe jused jfor jthe jtreatment jof jgout?
a. jMethotrexate
b. j5-fluorouracil
c. jColchicine
d. jSulfonamides j- jANS✓✓-C
Biomolecules jcan jbe jdivided jinto jfour jdifferent jclasses. jWhich jof jthe jfollowing
jis jNOT ja jmajor jclass jof jbiomolecule?
a. jLipids
b. jCarbohydrates
c. jNucleic jAcids
d. jFatty jAcids j- jANS✓✓-D
Which jof jthe jfollowing jmolecules jare jthe jmajor jcomponents jof jthe jcollagen?
a. jCarbohydrates
complete solutions 2024
Which jof jthe jfollowing jamino jacids jhas ja jrelatively juncharged jside jchain junder
jphysiological jconditions:
a. jArginine
b. jAspartate
c. jGlutamate
d. jLysine
e. jHistidine j- jANS✓✓-E
Which jof jthe jfollowing jbest jdescribes jtheir jarrangement jof jamino jacid jside
jchains jin jan jalpha jhelix:
a. jThe jside jchains jpoint joutward jaway jfrom jthe jhelical jaxis
b. jThe jside jchains jpoint jinward jtoward jthe jcenter jof jthe jhelix
c. jThe jside jchains jpoint jtoward jthe jN-terminal jend jof jthe jhelix
d. jThe jside jchains jpoint jtoward jthe jC-terminal jend jof jthe jhelix
e. jThe jside jchains jpoint jtoward jthe jnearest jbeta jsheet j- jANS✓✓-A
Which jof jthe jfollowing jsecondary jstructures jis jmost jlikely jto jbe jfound jin ja
jmembrane-embedded jportion jof ja jprotein:
a. jAn jalpha jhelix jcomposed jentirely jof jhydrophobic jresidues
b. jAn jalpha jhelical jcoiled jcoil
c. jA jsingle jextended jbeta jstrand
d. jAn jopen jparallel jbeta jsheet jcomposed jof jhydrophobic jresidues
e. jAn jopen jparallel jbeta jsheet jcomposed jof jhydrophilic jresidues j- jANS✓✓-A
Which jof jthe jfollowing jis jnecessarily jcharacterized jby ja jcovalent jlinkage:
a. jBase-pairing jinteraction
b. jDisulfide jbond
c. jHydrogen jbond
d. jInduced jfit
e. jVan jder jWaals jinteraction j- jANS✓✓-B
,Enzymes jthat jare jactivated jby jspecific jproteolytic jcleavage jare jcalled:
a. jIsozymes
b. jZymogens
c. jAllosteric
d. jHeterozymes
e. jNuclease j- jANS✓✓-B
Denature jof jproteins jby jgastric jacids jis jdue jto jthe jdisruption jof j_________ jby
jlow jpH:
a. jPeptide jbonds
b. jDisulfide jbonds
c. jIonic jbonds jand jhydrogen jbonds
d. jHydrophobic jinteractions
e. jEster jbonds j- jANS✓✓-C
Deficiency jof jwhich jof jthe jfollowing jenzyme jleads jto jthe jlactose jintolerance?:
a. jMaltase
b. jLactase
c. jSucrase
d. jAlpha-amylase
e. jAlpha-glucosidase j- jANS✓✓-B
________ jare jmolecules jthat jaid jin jlipid jabsorption. jThey jare jsynthesized jfrom
jcholesterol jin jthe jliver jand jsecreted jfrom jthe j________.:
a. jBile jsalts; jpancreas
b. jBile jsalts; jgall jbladder
c. jBile jsalts; jintestine
d. jLipases; jpancreas
e. jCholesterol jesterase; jgall jbladder j- jANS✓✓-B
What jis jthe jfunction jof jApoCII jin jthe jchylomicrons?:
a. jIt jis jrecognized jby jhepatic jreceptors jfor jrecycling
b. jIt jis jthe jstructure jprotein jfor jthe jformation jof jchylomicrons
c. jIt jis jrequired jfor jthe jtransportation jof jchylomicrons jin jthe jblood
d. jIt jis jnecessary jfor jthe jactivation jof jlipoprotein jlipase
e. jIt jis jinvolved jin jthe jre-synthesis jof jTAG jin jthe jsmall jintestine j- jANS✓✓-D
Which jof jthe jfollowing janswers jcompletes jthe jsentence jcorrectly? jCytosine jis
ja?
a. jPurine jbase
b. jPurine jnucleoside
, c. jPyrimidine jbase
d. jPyrimidine jnucleoside j- jANS✓✓-C
During jthe jsynthesis jof jpyrimidine jnucleotides, jthe jpyrimidine jring jframework
jthat jbecomes jattached jto jthe jribose jis?
a. jUracil
b. jOrotate
c. jCytosine
d. jAdenine j- jANS✓✓-B
Which jone jof jthe jfollowing jenzymes jof jnucleotide jmetabolism jis jcorrectly
jpaired jwith jits jpharmacological jinhibitor?
a. jDihydrofolate jreductase- j- j-methotrexate
b. jIMP jdehydrogenase- j- j-hydroxyurea
c. jRibonucleotide jreductase- j- j-5-fluorouracil
d. jThymidylate jsynthase- j- j-allopurinol
e. jXanthine joxidase- j- j-probencid j- jANS✓✓-A
What jis jthe jbiochemical jdeficiency jthat jleads jto jsevere jcombined
jimmunodeficiency jdisease j(SCID)?
a. jNucleoside jphosphorylase
b. jXanthine joxidase
c. jAdenosine jdeaminase
d. jAll jof jthe jabove j- jANS✓✓-C
Which jof jthe jfollowing jchemicals jcan jbe jused jfor jthe jtreatment jof jgout?
a. jMethotrexate
b. j5-fluorouracil
c. jColchicine
d. jSulfonamides j- jANS✓✓-C
Biomolecules jcan jbe jdivided jinto jfour jdifferent jclasses. jWhich jof jthe jfollowing
jis jNOT ja jmajor jclass jof jbiomolecule?
a. jLipids
b. jCarbohydrates
c. jNucleic jAcids
d. jFatty jAcids j- jANS✓✓-D
Which jof jthe jfollowing jmolecules jare jthe jmajor jcomponents jof jthe jcollagen?
a. jCarbohydrates
