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Acid/base balance, water/fluid balance, electrolyte balance, toxin/waste product
removal, blood pressure regulation, erythropoietin production, vitamin D metabolism
Acute renal failure cause
drug toxicity, trauma, dehydration, infection
Acute renal failure characteristics
sudden onset, severe, usually reversible
Chronic kidney failure characteristics
slow onset, progressive, permanent
chronic kidney failure causes
diabetes & hypertension
Lab signs of renal failure
Elevated BUN/creatinine, phosphorous, potassium, proteinuria (protein in urine)
signs of renal failure
anemia, nerve damage, yellow/gray skin, fluid overload, shortness of breath, edema,
hypertension
Vascular refill
during dialysis, fluid shifts from other compartments back into the intravascular space
Where fluid is removed from dialysis
intravascular space (blood)
What happens if fluid is removed at a faster rate during dialysis?
pt will experience hypotension, muscle cramping
EDW too high
not enough fluid being removed
Signs EDW is too high
hypertension, headache, SOB, crackles in lung bases, edema, distended neck and
veins
EDW too low
too much fluid being removed
Signs EDW is too low
dizziness, nausea, vomiting, hypotension, craps, fatigue
What factors affect diffusion and clearance of dialysis?
tx time, BFR, DFR, Dialyzer size
Transmembrane pressure
blood pressure + dialysate side pressure across dialyzer membrane
what keeps dialysate from moving into the bloodstream?
pressure on blood side must be equal or more than dialysate pressure
ultrafiltration rate
Rate at which fluid moves from blood into dialysate through the membrane; rate
depends on TMP (rate of fluid removal from blood) [ml/hr]
UFR Calculation