NR 507 Midterm Exam Questions and Answers
Graded A 2024
Hypersensitivity: Type 1 - ANSWER>>-Mediated IgE
-inflammation due to mast cell degranultion
-anaphylactic, asthma, hay fever
treatment: epinephrine
Hypersensitivity: Type 2 - ANSWER>>-Cytotoxic reaction: tissue specific
-binds to the antigen ON THE CELL SURFACE
-macrophages are primary effectors cells involved
cause tissue damage or alter function
Hypersensitivity 2 - ANSWER>>-Graves Disease (hyperthyroidism) -alters function
not destroy
-blood transfusions reaction- transfused erythrocytes are destroyed by
agglutination or lysis
-drug allergies
-hemolytic anemia
Hypersensitivity: type 3 - ANSWER>>-Not organ specific
-antibody binds to soluble antigen OUTSIDE THE CELL SURFACE that was released
into the blood or bodily fluids, and the complex is then deposited in the tissues
Hypersensitivity: Type 3 - ANSWER>>-rheumatoid arthritis
-Systemic Lupus Erythematosus (SLE)
-Raynaud's
Hives (urticaria) - ANSWER>>Hypersensitivity Type 1
First responders to innate the immune system - ANSWER>>Neutrophils
,Allergic contact dermatitis - ANSWER>>Hypersensitivity Type IV
Type 2 cytotoxic hypersensitivity mediated by: - ANSWER>>-IgG IgM
-macrophages are primary effort cells
-
Serum Sickness - ANSWER>>type 3 hypersensitivity
Hypersensitivity IV, - ANSWER>>-is more of a delayed immune response.
-mediated T-cells attack tissue directly (no antibodies)
Autoimmune - ANSWER>>-diseases in which the body makes antibodies directed
against its own tissues
-
Primary immunodeficiency - ANSWER>>-Genetic; inherited
-result of single gene defects
-B and T cell deficiencies
secondary immunodeficiency - ANSWER>>-acquired
Common cause of secondary immunodeficiency - ANSWER>>Malnutrition
Most patients diagnosed with SLE will have a positive ? - ANSWER>>antinuclear
antibody (ANA)
SLE (lupus) - ANSWER>>-Facial rash
-vasculitis
- tissue inflammation
Renal disease associated with autoimmunity? - ANSWER>>Glomerulonephritis
Sjogren's syndrome - ANSWER>>Inflammation in salivary and lacrimal glands
, SLE - ANSWER>>Autoantibodies and auto-active t-cells against DNA and
nucleoprotein
Sjögren's syndrome immune changes: - ANSWER>>Autoantibodies and auto-
reactive t-cells against apoptotic cells
rheumatoid arthritis manifestations: - ANSWER>>Joint inflammation, stiffness,
pain, loss of range of motion
Rheumatoid Arthritis immune changes: - ANSWER>>T-cells and B cells against
joint associated antigens
MS manifestations - ANSWER>>Formation of sclerotic plaque in the brain, leads
to Muscle weakness and ataxia
MS immune changes - ANSWER>>T-cells against brain antigens
___ measures the average size of RBCs - ANSWER>>MCV
Anemia occur by... - ANSWER>>-impaired RBC production
-excessive blood loss
- increased RBC production
microlytic anemia is characterized by hyper chromic RBS: - ANSWER>>Hereditary
spherocytosis
Anemia - ANSWER>>-"without blood"
4.7-6.1mcl - ANSWER>>Normal for men RBC
4.5-5.2mcL - ANSWER>>Normal for women RBC
Graded A 2024
Hypersensitivity: Type 1 - ANSWER>>-Mediated IgE
-inflammation due to mast cell degranultion
-anaphylactic, asthma, hay fever
treatment: epinephrine
Hypersensitivity: Type 2 - ANSWER>>-Cytotoxic reaction: tissue specific
-binds to the antigen ON THE CELL SURFACE
-macrophages are primary effectors cells involved
cause tissue damage or alter function
Hypersensitivity 2 - ANSWER>>-Graves Disease (hyperthyroidism) -alters function
not destroy
-blood transfusions reaction- transfused erythrocytes are destroyed by
agglutination or lysis
-drug allergies
-hemolytic anemia
Hypersensitivity: type 3 - ANSWER>>-Not organ specific
-antibody binds to soluble antigen OUTSIDE THE CELL SURFACE that was released
into the blood or bodily fluids, and the complex is then deposited in the tissues
Hypersensitivity: Type 3 - ANSWER>>-rheumatoid arthritis
-Systemic Lupus Erythematosus (SLE)
-Raynaud's
Hives (urticaria) - ANSWER>>Hypersensitivity Type 1
First responders to innate the immune system - ANSWER>>Neutrophils
,Allergic contact dermatitis - ANSWER>>Hypersensitivity Type IV
Type 2 cytotoxic hypersensitivity mediated by: - ANSWER>>-IgG IgM
-macrophages are primary effort cells
-
Serum Sickness - ANSWER>>type 3 hypersensitivity
Hypersensitivity IV, - ANSWER>>-is more of a delayed immune response.
-mediated T-cells attack tissue directly (no antibodies)
Autoimmune - ANSWER>>-diseases in which the body makes antibodies directed
against its own tissues
-
Primary immunodeficiency - ANSWER>>-Genetic; inherited
-result of single gene defects
-B and T cell deficiencies
secondary immunodeficiency - ANSWER>>-acquired
Common cause of secondary immunodeficiency - ANSWER>>Malnutrition
Most patients diagnosed with SLE will have a positive ? - ANSWER>>antinuclear
antibody (ANA)
SLE (lupus) - ANSWER>>-Facial rash
-vasculitis
- tissue inflammation
Renal disease associated with autoimmunity? - ANSWER>>Glomerulonephritis
Sjogren's syndrome - ANSWER>>Inflammation in salivary and lacrimal glands
, SLE - ANSWER>>Autoantibodies and auto-active t-cells against DNA and
nucleoprotein
Sjögren's syndrome immune changes: - ANSWER>>Autoantibodies and auto-
reactive t-cells against apoptotic cells
rheumatoid arthritis manifestations: - ANSWER>>Joint inflammation, stiffness,
pain, loss of range of motion
Rheumatoid Arthritis immune changes: - ANSWER>>T-cells and B cells against
joint associated antigens
MS manifestations - ANSWER>>Formation of sclerotic plaque in the brain, leads
to Muscle weakness and ataxia
MS immune changes - ANSWER>>T-cells against brain antigens
___ measures the average size of RBCs - ANSWER>>MCV
Anemia occur by... - ANSWER>>-impaired RBC production
-excessive blood loss
- increased RBC production
microlytic anemia is characterized by hyper chromic RBS: - ANSWER>>Hereditary
spherocytosis
Anemia - ANSWER>>-"without blood"
4.7-6.1mcl - ANSWER>>Normal for men RBC
4.5-5.2mcL - ANSWER>>Normal for women RBC
