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If pH is greater than the pKa, the compound will prefer to ________ protons.
lose
pKa =
how likely compounds will lose protons (-logKa)
What do acids form in water?
H+ ions
What do bases form in water?
-OH ions
What are the traits of Bronsted-Lowry?
-Acid = H+ (proton) donor
-Base = H+ (proton) acceptor
What is the acid dissociation constant (Ka) a measure of?
The strength of an acid
Strong acids like to __________ protons and shift the equilibrium to the
___________.
donate, right
What is the pKa value a direct measure of?
The strength of an acid
Higher pKa =
weaker acid and stronger base
Lower pKa =
stronger acid and weaker base
The stronger the acid, the more the equilibrium wants to move to the __________,
to release H+
right
The weaker the acid, the more the equilibrium wants to move to the _________, to
prevent release of H+
left
Very stable conjugate base =
strong acid
Unstable conjugate base =
weak acid
What are the 3 parameters to consider when deciding on relative acidity?
1. Electronegativity
2. Resonance
3. Induction
How can electronegativity determine the stability of a conjugate base?
More electronegative atoms will make the conjugate base more stable
How can resonance determine the stability of a conjugate base?