USPS EXAM 2024 with answers
T/F Under USP 800 a low volume HD producing facility does not have to locate its
BSC or CACI in a negative pressure room - ANSWER: FALSE - was true under 797
Containment segregation compounding areas (C-SCA)are - ANSWER: separate
negative pressure areas with at least 12 air exchanges per hour
HDs with these levels of risk may be prepared in a BSC or CACI within a C -CSA -
ANSWER: low and moderate risk - but must have a BUD of NMT 12 hours
T/F under USP 800 HDs may be unpacked in either a neutral or negative pressure
room - ANSWER: TRUE - no positive pressure rooms
Under the USP 800 an entity must maintain a ________list of HD drugs and ______
add additional drugs to the list - ANSWER: NIOSH, may
The entity's list of HD must be reviewed at least ________ and updated - ANSWER:
yearly, whenever there is an addition to the NIOSH list
Antineoplastics on the HD list must remain in ________ so long as they are being
manipulated prior to dispensing - ANSWER: containment
It is up to the entity to determine containment strategies for these HD drugs -
ANSWER: non antineoplastics - entity must document these strategies
Understanding the fundamental practices and precautions and for continually
evaluating these procedures and the quality of final HDs to prevent harm to patients,
minimize exposure to personnel, and minimize contamination of the work and care
environment - ANSWER: responsibilities of all who handle HDs
Access to areas where HDs are handled must be - ANSWER: restricted to authorized
personnel
Areas where HDs are handled must be located - ANSWER: away from breakrooms,
patient/visitor areas
Before the entrance to HD handling areas must be - ANSWER: signs prominently
displayed denoting the area as hazardous
Four distinct areas that must be designated for HDs according to USP 800 - ANSWER:
1.) receipt and unpacking 2.) storage of HDs 3.) Nonsterile compounding (if
preformed) and 4.) sterile compounding (if preformed)
Two areas in which HDs may NOT be unpacked - ANSWER: sterile compounding
areas and positive pressure areas
, Neoplastic HDs should be stored on shelves which are _______ and have _________
- ANSWER: secured and have raised lips
Non-antineoplastic, reproductive risk only and final dosage forms of antineoplastic
drugs may be stored with - ANSWER: other inventory
T/F sterile and nonsterile HDs may be stored together - ANSWER: TRUE
Those medications which may be stored in the negative pressure buffer room -
ANSWER: sterile HDs - as long as the buffer room is 12 air changes per hour
Refrigerated antineoplastic HDs must be stored in - ANSWER: a dedicated
refrigerator within a negative pressure area with 12 air exchanges per hour or in a
containment segregated compounding area
If a refrigerator storing antineoplastic HDs is placed in a negative pressure buffer
room it must be placed in the room such that - ANSWER: the compressor is adjacent
to an exhaust system
Definition of containment primary engineering control under USP 800 - ANSWER: C-
PEC = a ventilated device meant to minimize worker and environmental exposure to
HDs when directly handling HDs
Definition of containment secondary engineering control under USP 800 - ANSWER:
C-SEC = is the room in which the C-PEC is placed
Definition of supplemental engineering controls under USP 800 - ANSWER: are
adjunct controls to offer additional levels of protection - such as drug transfer
devices
Sterile and non-sterile compounds of HDs must be prepared in - ANSWER: a C-PEC
located within a C-SEC
The C-SEC must have these attributes to comply with USP 800 - ANSWER: 1.) Be
externally vented through a HEPA filter 2.) Be physically separate from other
preparation areas 3.) have negative pressure between 0.01 and 0.03 inches of water
A C-PEC must operate ___________ if it supplies the negative pressure or if it is used
for __________ compounding - ANSWER: continuously, sterile
If a C-PEC must be powered down you must wait this amount of time prior to
starting compounding again - ANSWER: the manufacturer specified recovery time
In the event of accidental eye/skin exposure access to a _________ and
___________is required within _________ - ANSWER: a sink and emergency eye
wash station with running hot/cold water within the C-SEC
T/F Under USP 800 a low volume HD producing facility does not have to locate its
BSC or CACI in a negative pressure room - ANSWER: FALSE - was true under 797
Containment segregation compounding areas (C-SCA)are - ANSWER: separate
negative pressure areas with at least 12 air exchanges per hour
HDs with these levels of risk may be prepared in a BSC or CACI within a C -CSA -
ANSWER: low and moderate risk - but must have a BUD of NMT 12 hours
T/F under USP 800 HDs may be unpacked in either a neutral or negative pressure
room - ANSWER: TRUE - no positive pressure rooms
Under the USP 800 an entity must maintain a ________list of HD drugs and ______
add additional drugs to the list - ANSWER: NIOSH, may
The entity's list of HD must be reviewed at least ________ and updated - ANSWER:
yearly, whenever there is an addition to the NIOSH list
Antineoplastics on the HD list must remain in ________ so long as they are being
manipulated prior to dispensing - ANSWER: containment
It is up to the entity to determine containment strategies for these HD drugs -
ANSWER: non antineoplastics - entity must document these strategies
Understanding the fundamental practices and precautions and for continually
evaluating these procedures and the quality of final HDs to prevent harm to patients,
minimize exposure to personnel, and minimize contamination of the work and care
environment - ANSWER: responsibilities of all who handle HDs
Access to areas where HDs are handled must be - ANSWER: restricted to authorized
personnel
Areas where HDs are handled must be located - ANSWER: away from breakrooms,
patient/visitor areas
Before the entrance to HD handling areas must be - ANSWER: signs prominently
displayed denoting the area as hazardous
Four distinct areas that must be designated for HDs according to USP 800 - ANSWER:
1.) receipt and unpacking 2.) storage of HDs 3.) Nonsterile compounding (if
preformed) and 4.) sterile compounding (if preformed)
Two areas in which HDs may NOT be unpacked - ANSWER: sterile compounding
areas and positive pressure areas
, Neoplastic HDs should be stored on shelves which are _______ and have _________
- ANSWER: secured and have raised lips
Non-antineoplastic, reproductive risk only and final dosage forms of antineoplastic
drugs may be stored with - ANSWER: other inventory
T/F sterile and nonsterile HDs may be stored together - ANSWER: TRUE
Those medications which may be stored in the negative pressure buffer room -
ANSWER: sterile HDs - as long as the buffer room is 12 air changes per hour
Refrigerated antineoplastic HDs must be stored in - ANSWER: a dedicated
refrigerator within a negative pressure area with 12 air exchanges per hour or in a
containment segregated compounding area
If a refrigerator storing antineoplastic HDs is placed in a negative pressure buffer
room it must be placed in the room such that - ANSWER: the compressor is adjacent
to an exhaust system
Definition of containment primary engineering control under USP 800 - ANSWER: C-
PEC = a ventilated device meant to minimize worker and environmental exposure to
HDs when directly handling HDs
Definition of containment secondary engineering control under USP 800 - ANSWER:
C-SEC = is the room in which the C-PEC is placed
Definition of supplemental engineering controls under USP 800 - ANSWER: are
adjunct controls to offer additional levels of protection - such as drug transfer
devices
Sterile and non-sterile compounds of HDs must be prepared in - ANSWER: a C-PEC
located within a C-SEC
The C-SEC must have these attributes to comply with USP 800 - ANSWER: 1.) Be
externally vented through a HEPA filter 2.) Be physically separate from other
preparation areas 3.) have negative pressure between 0.01 and 0.03 inches of water
A C-PEC must operate ___________ if it supplies the negative pressure or if it is used
for __________ compounding - ANSWER: continuously, sterile
If a C-PEC must be powered down you must wait this amount of time prior to
starting compounding again - ANSWER: the manufacturer specified recovery time
In the event of accidental eye/skin exposure access to a _________ and
___________is required within _________ - ANSWER: a sink and emergency eye
wash station with running hot/cold water within the C-SEC
