NSG 3032 Pharmacotherapeutics II EXAM 1 LATEST
2024/2025 SOUTH UNIVERSITY WITH RATIONALE
Prostaglandin analogs - ANSWER: latanoprost
Prostaglandin analogs - ANSWER: Lantanoprostene
Prostaglandin analogs - ANSWER: Brimatoprost
Prostaglandin analogs - ANSWER: travoprost
Prostaglandin analogs - ANSWER: Tafluprost
Beta blocker - ANSWER: Timolol, betaxolol, certeolol, levobunolol, metipranoloo
CAIs - ANSWER: Dorzolamide, brinzolamide, acetazolamide, methazolamide
Alpha agonists - ANSWER: Brimonidine
Apraclonidine, pilocarpine
Which is first line? - ANSWER: Prostaglandin analogs, beta blockers
What is second line? - ANSWER: Dorzolamide, brinzolamide, apraclonidine
What is the third line? - ANSWER: Acetazolamide, methazolamide
How do prostaglandin analogs work? - ANSWER: increase aqueous outflow
How do beta blockers, alpha agonists and CAIs work? - ANSWER: Decrease aqueous
humor production
What is the goal IOP lowering? - ANSWER: 20-30%
Is open angle glaucoma or closed angle glaucoma more severe? - ANSWER: Closed
angle
How do we monitor glaucoma? - ANSWER: Check in with patient every 4-6 weeks
while adjusting meds, once patient is at goal IOP we check them every 3-4 months,
patient gets yearly eye exams
What if the patient has no response/intolerance? - ANSWER: Switch to a different
agent
What if patient has partial response? - ANSWER: Add on another class
, What meds might worsen glaucoma? - ANSWER: Corticosteroids and ophthalmic
anticholinergic drugs
What are treatments for closed angle glaucoma? - ANSWER: Oral glycerin, IV
mannitol, pilocarpin (if IOP <60), all agents that decrease aqueous humor, topical
corticosteroids, iridectomy/surgery
PDE-5 inhibitors - ANSWER: Sildenafil, tidalafil, vardenafil, avanafil
Which PDE5 inhibitor doesn't require renal adjustment? - ANSWER: Vardenafil
Which PDE-5 inhibitor can be used in patients over 65? - ANSWER: Tadalafil and
avanafil
Which PDE-5 inhibitor has an ODT formulation? - ANSWER: Vardenafil
What medications cause ED? - ANSWER: Beta blockers, diphenhydramine, TCAs,
benzodiazepines, finasteride and dutasteride
What is the treatment algorithm for ED? - ANSWER: Treat underlying causes and
remove meds that cause ED
PDE-5 inhibitors and titration up dose, maybe vacuum erection device
Intraurethral injection/suppository/pellets
What are adverse effects of PDE-5 inhibitors? - ANSWER: Flushing, hypotension,
headache
What are rare but serious effects of PDE-5 inhibitors? - ANSWER: Priapism and
NAION
What is a normal testosterone level? - ANSWER: 300-1100 ng/dL
What should patients avoid when taking PDE-5 inhibitors? - ANSWER: Nitrates,
excessive alcohol, alpha blockers, patients predisposed to priapism (sickle cell
anemia)
What can patients use if PDE-5 inhibitors failed? - ANSWER: Prostaglandin E1 -
alprostadil or MUSE
Most common and preferred ROA for testosterone? - ANSWER: IM Q2-4 weeks
What are counseling points for topical testosterone? - ANSWER: Keep away from
women and children, wash hands after application, avoid water for 2 hours after
application
What are different dosage forms of testosterone? - ANSWER: Patch, gel, spray,
solution, nasal gel, buccal system
2024/2025 SOUTH UNIVERSITY WITH RATIONALE
Prostaglandin analogs - ANSWER: latanoprost
Prostaglandin analogs - ANSWER: Lantanoprostene
Prostaglandin analogs - ANSWER: Brimatoprost
Prostaglandin analogs - ANSWER: travoprost
Prostaglandin analogs - ANSWER: Tafluprost
Beta blocker - ANSWER: Timolol, betaxolol, certeolol, levobunolol, metipranoloo
CAIs - ANSWER: Dorzolamide, brinzolamide, acetazolamide, methazolamide
Alpha agonists - ANSWER: Brimonidine
Apraclonidine, pilocarpine
Which is first line? - ANSWER: Prostaglandin analogs, beta blockers
What is second line? - ANSWER: Dorzolamide, brinzolamide, apraclonidine
What is the third line? - ANSWER: Acetazolamide, methazolamide
How do prostaglandin analogs work? - ANSWER: increase aqueous outflow
How do beta blockers, alpha agonists and CAIs work? - ANSWER: Decrease aqueous
humor production
What is the goal IOP lowering? - ANSWER: 20-30%
Is open angle glaucoma or closed angle glaucoma more severe? - ANSWER: Closed
angle
How do we monitor glaucoma? - ANSWER: Check in with patient every 4-6 weeks
while adjusting meds, once patient is at goal IOP we check them every 3-4 months,
patient gets yearly eye exams
What if the patient has no response/intolerance? - ANSWER: Switch to a different
agent
What if patient has partial response? - ANSWER: Add on another class
, What meds might worsen glaucoma? - ANSWER: Corticosteroids and ophthalmic
anticholinergic drugs
What are treatments for closed angle glaucoma? - ANSWER: Oral glycerin, IV
mannitol, pilocarpin (if IOP <60), all agents that decrease aqueous humor, topical
corticosteroids, iridectomy/surgery
PDE-5 inhibitors - ANSWER: Sildenafil, tidalafil, vardenafil, avanafil
Which PDE5 inhibitor doesn't require renal adjustment? - ANSWER: Vardenafil
Which PDE-5 inhibitor can be used in patients over 65? - ANSWER: Tadalafil and
avanafil
Which PDE-5 inhibitor has an ODT formulation? - ANSWER: Vardenafil
What medications cause ED? - ANSWER: Beta blockers, diphenhydramine, TCAs,
benzodiazepines, finasteride and dutasteride
What is the treatment algorithm for ED? - ANSWER: Treat underlying causes and
remove meds that cause ED
PDE-5 inhibitors and titration up dose, maybe vacuum erection device
Intraurethral injection/suppository/pellets
What are adverse effects of PDE-5 inhibitors? - ANSWER: Flushing, hypotension,
headache
What are rare but serious effects of PDE-5 inhibitors? - ANSWER: Priapism and
NAION
What is a normal testosterone level? - ANSWER: 300-1100 ng/dL
What should patients avoid when taking PDE-5 inhibitors? - ANSWER: Nitrates,
excessive alcohol, alpha blockers, patients predisposed to priapism (sickle cell
anemia)
What can patients use if PDE-5 inhibitors failed? - ANSWER: Prostaglandin E1 -
alprostadil or MUSE
Most common and preferred ROA for testosterone? - ANSWER: IM Q2-4 weeks
What are counseling points for topical testosterone? - ANSWER: Keep away from
women and children, wash hands after application, avoid water for 2 hours after
application
What are different dosage forms of testosterone? - ANSWER: Patch, gel, spray,
solution, nasal gel, buccal system
