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amniocentesis and chorionic villus sampling - CORRECT ANSWER: invasive
techniques in which amniotic fluid or fetal cells are obtained for genetic analysis
Amniocentesis procedure - CORRECT ANSWER: Amniocentesis involves placing a
needle transabdominally through the uterus into the amniotic sac and withdrawing some
of the fluid. The fluid contains sloughed fetal cells that can be cultured. These cultured
cells can then be karyotyped and also utilized in DNA tests. The cultures take about 5 to
7 days to grow, but a newer technique—fluorescent in-situ hybridization (FISH)—can be
used to identify aneuploidy and gets results in 24 to 48 hours.
BI-RADS - CORRECT ANSWER: Breast imaging reporting and data system (0-6)
0: incomplete (young) - get US or another mammogram?
1: negative- routine screening
2: benign- routine screening
3: probably benign- short term f/u
4: suspicious- consider biopsy
5: highly suspicious- biopsy
6: known malignancy
bioavailable testosterone - CORRECT ANSWER: measures free testosterone and
testosterone that's loosely attached to a blood protein called albumin. This test isn't
commonly done. But like a free testosterone test, it may help diagnose certain medical
conditions.
blood typing - CORRECT ANSWER: The blood of one person is different from another's
due to the presence of antigens on the surface of the erythrocytes. The major method of
, typing blood is the ABO system and includes types A, B, O, and AB. The other major
method of typing blood is the Rh factor, consisting of the two types, Rh+ and Rh-.
Bone densitometry (DEXA) - CORRECT ANSWER: x-ray technique for determining
density of bone performed in the nuclear med area. diagnostic for osteoporosis. also
used for unexplained fractures, GI malabsorption, renal diseases, endocrinopathies.
Breast cancer tumor analysis - CORRECT ANSWER: done by biopsy. aneuploid=not
good diploid=favorable.
S-phase fraction >5.5% is unfavorable <5.5 is not favorable
HER2 protein--associated with higher aggressiveness in breast ca
Cathepsin D >10% unfavorable <10% favorable
p52 protein--overexpressed in aggressive breast cancer
Ki67--associated with more aggressive breast ca
breast cyst and nipple discharge fluid analysis - CORRECT ANSWER: used to make dx
of cancer in breast cysts and to exclude dx of cancer for nipple discharge
most cysts are benign. nearly all nonbloody nipple dc is benign.
nipple dc smear dc onto microscope slide and fix with etoh or commercial spray. must
be fixed before drying. label slide.
for cyst aspiration: id by US, sterilize surrounding skin, use a needle for aspiration of
fluid until cyst is completely collapsed. fludi injected into fixative solution and labeled
Breast Ultrasound - CORRECT ANSWER: -helpful diagnostic tool to differentiate
between a benign tumor from a malignant tumor
-useful in women who have dense breasts with fibrocystic changes
-monitor a cyst
-unlike mammogram, will not detect microcalcifications