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electronic systems for cancer diagnosis

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electronic systems for cancer diagnosis Week 2 : Understanding the change in cells or tissue morphology. Developing strategies for diagnosis based on Morphology changes.

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Week 2 Photolithography and micromachining techniques



Introduction to photolithography

### Key Points on Photolithography

1. **Purpose of Photolithography**:
- **Definition**: Photolithography is a process used to create small structures on a substrate
(typically a silicon wafer) through the selective exposure of a light-sensitive material
(photoresist) to UV light.
- **Applications**: Essential for fabricating microelectronic devices, MEMS, and various
microstructures.

2. **Basic Steps in Photolithography**:
- **Wafer Cleaning**: Critical to remove contaminants. This includes etching silicon dioxide
with HF dip, rinsing with deionized water, and drying.
- **Primer Coating**: Applying a primer like HMDS to enhance photoresist adhesion.
- **Spin Coating Photoresist**: Dispensing photoresist on the wafer and spinning it to achieve
uniform thickness based on RPM and time.
- **Soft Bake**: Partial solvent evaporation to improve adhesion and uniformity.
- **Mask Alignment and Exposure**: Aligning a mask over the photoresist-coated wafer and
exposing it to UV light.
- **Development**: Immersing the wafer in a developer solution to remove either the exposed
(for positive photoresist) or unexposed areas (for negative photoresist).
- **Hard Bake**: Final curing of the photoresist to improve durability and etch resistance.

3. **Types of Photoresist**:
- **Positive Photoresist**: Exposed areas become weaker and are washed away during
development (e.g., AZ-3312).
- **Negative Photoresist**: Exposed areas become stronger and remain after development
(e.g., SU-8).

4. **Mask Types**:
- **Bright Field Mask**: Light passes through transparent areas to expose the photoresist.
- **Dark Field Mask**: Light is blocked in certain areas, creating patterns by exposing
surrounding regions.

5. **Challenges and Considerations**:
- **Over/Under Development**: Critical timing during development affects pattern integrity.

, - **Mask Defects**: Issues like chrome spots, bridging, or pinholes can lead to defective
patterns.
- **Environmental Control**: Maintaining cleanroom conditions to prevent contamination is
essential.

6. **Advancements in Technology**:
- **Automated Mask Aligners**: Machines like the MA 200 compact enhance precision and
speed in aligning masks to wafers, accommodating various substrate types and thicknesses.

7. **Applications in Device Fabrication**:
- Used in creating components for sensors, micro-heaters, and other micro-devices,
particularly in clinical and telecommunication technologies.

This process is fundamental in microfabrication and allows for the creation of intricate patterns
necessary for modern electronic and mechanical devices.


Photolithography: Mask Aligner

Sure! Here are the key points from the lecture on photolithography and the development of a
cost-effective mask aligner:

1. **Photolithography Overview**:
- Process involves cleaning substrates, applying primer and photoresist, soft-baking, aligning
masks, exposing to UV light, and developing.

2. **Current Equipment Costs**:
- Commercial mask aligners are expensive, ranging from 50 lakh to over 2 crores.

3. **Objective**:
- Develop a low-cost mask aligner that universities can afford to bridge the gap in access to
MEMS technology.

4. **Photolithography Steps**:
- Clean substrate → Spin coat primer/photoresist → Soft-bake → Align and expose →
Develop → Etch.

5. **Alignment Importance**:
- Use alignment marks on masks and wafers for precise pattern transfer; alignment marks of
subsequent masks should be smaller.

6. **Mask Aligner Components**:
- Includes X-Y-Theta stage, UV exposure unit, mask holder, wafer holder, and split-field
microscope for alignment checks.

, 7. **Designing an Affordable Mask Aligner**:
- Focus on using simpler components and 3D printing technologies to create a functional
design.

8. **Camera and Mask Holder Design**:
- Camera assembly for alignment checks; mask holder designed to accommodate different
mask sizes with vacuum features.

9. **Wafer Holder Functionality**:
- Designed to hold wafers securely using vacuum; can handle 2-inch to 4-inch wafers.

10. **Next Steps**:
- Future modules will cover the design and implementation of the mask alignment system and
its integration with UV exposure systems.

The lecture emphasizes hands-on learning and encourages students to explore practical
solutions in MEMS fabrication.
Photolithography: Designing Mask Aligner

Certainly! Here are the key points from the discussion on mask alignment systems and their
integration:

1. **Mask Alignment System Components**:
- Joystick for X, Y, and Theta movement.
- Cameras for simultaneous image acquisition (split-field microscope).
- Live video display for capturing alignment marks.
- UV light source and both mask and wafer holders.

2. **Mechanical and Electronic Integration**:
- After designing mechanical components, electronics must be integrated.
- Use programming languages (C, C++, Java) to create a graphical user interface (GUI) for
system operation.

3. **Front-to-Back Alignment**:
- Current design supports only front alignment; front-to-back alignment is more complex and
used for etching on both sides of a substrate.

4. **User Interface Features**:
- Control buttons for camera operation, alignment, exposure settings, and timing adjustments
based on material properties.

5. **UV Light Source Alternatives**:

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