Chemicals in combination can produce different biological responses than the responses seen when
exposure is to one chemical alone.
True
False - Answers True
________ is the most common route of exposure leading to a toxic dose in the work environment
Injection
Ingestion
Inhalation
Eye/Skin contact - Answers
LD 50 of 25 mg/m3 means that a concentration of 25 mg/m3 of a certain substance indicates:
50 people out of a group of 80 exposed to a concentration 25 mg/m3 of a substance were shown to
have experienced a fatal dose.
50% of the concentration of a substance cause fatality in those be exposed.
A concentration of 25 mg/m3 of a substance is shown to have been fatal to 50 percent of a test group of
animals.
LD 50 is a fictitious term and does not indicate anything. - Answers A concentration of 25 mg/m3 of a
substance is shown to have been fatal to 50 percent of a test group of animals.
Factors affecting response to chemical exposure include:
Toxicity
Route of exposure
, Chemical dose
All of the above - Answers All of the above
________ provide most of what we know about the dangerous effects of toxic substances.
Epidemiological studies
Animal studies
Estimation studies
Actual exposures to a chemical in the workplace - Answers Epidemiological studies
Animal studies
Example of chemical ________ are carbon monoxide and hydrogen cyanide.
Hepatoxins
Hematoxins
Asphyxiants
Nephrotoxins - Answers Asphyxiants
The ACGIH publication: ________ for Chemical Substances and Physical Agents, OSHA standard 29 CFR
part 1910.1000, and other standards reference identify substances that can be readily absorbed through
the skin, mucous membranes, and/or eyes by either airborne exposures or direct contact with a liquid.
Threshold Limit Values
HAZCOM
Right-to-know
SDS - Answers Threshold Limit Values
Polyurethane foam, when burnt, gives off:
Sulfuric acid