MD1TALK
Neonatal Jaundice🌟
Types:
1) Unconjugated hyperbilirubinemia
2) Conjugated hyperbilirubinemia
Etiology of hyperbilirubinemia
MD1TALK
unconjugated
conjugated
Hemolysis present Hemolysis absent
• Congenital infection • ABO incompatibility • Physiological
(torch) • Rhesus isoimmunization • Breast milk
• Sepsis • Glucose 6-phosphate • Pyloric stenosis
• Biliary atresia dehydrogenase deficiency • Hypothyroidism
• Choledochal cyst • Hereditary spherocytosis
• Thalassemis
physiologic Jaundice:
Most common cause of Jaundice in neonate, occurs at 2nd or 3rd day
Is a diagnosis of exclusion
In term infants a peak indirect reacting bilirubin level of no more than
12 mg/dl on day 3 of life.
In premature infants, the peak is higher (15 mg/dl) and occurs later (5th
day).
The rate of bilirubin rise is less than 5 mg/dl per 24 hours.
Usually child is not febrile and eating well.
pathologic jaundice:
Jaundice on the 1st day of life is always pathologic.
Bilirubin level increases more than 0.5 mg/dl/hr
Peak bilirubin is greater than 13 mg/dl in term infants
Hepatosplenomegaly
Anemia
Neonatal Jaundice🌟
Types:
1) Unconjugated hyperbilirubinemia
2) Conjugated hyperbilirubinemia
Etiology of hyperbilirubinemia
MD1TALK
unconjugated
conjugated
Hemolysis present Hemolysis absent
• Congenital infection • ABO incompatibility • Physiological
(torch) • Rhesus isoimmunization • Breast milk
• Sepsis • Glucose 6-phosphate • Pyloric stenosis
• Biliary atresia dehydrogenase deficiency • Hypothyroidism
• Choledochal cyst • Hereditary spherocytosis
• Thalassemis
physiologic Jaundice:
Most common cause of Jaundice in neonate, occurs at 2nd or 3rd day
Is a diagnosis of exclusion
In term infants a peak indirect reacting bilirubin level of no more than
12 mg/dl on day 3 of life.
In premature infants, the peak is higher (15 mg/dl) and occurs later (5th
day).
The rate of bilirubin rise is less than 5 mg/dl per 24 hours.
Usually child is not febrile and eating well.
pathologic jaundice:
Jaundice on the 1st day of life is always pathologic.
Bilirubin level increases more than 0.5 mg/dl/hr
Peak bilirubin is greater than 13 mg/dl in term infants
Hepatosplenomegaly
Anemia
