HEMA MOCKBOARD REVIEWER QUESTIONS AND
ANSWERS A+ GRADED .Buy Quality Materials!
Typical laboratory findings in TTP and HUS include:
Schistocytosis and thrombocytopenia
Anemia and reticulocytopenia
Reduced levels of lactate dehydrogenase and aspartate aminotransferase
Increased levels of free plasma hemoglobin and serum
more than one possible answer
none of these choices
Schistocytosis and thrombocytopenia
Which of the following is an acquired red cell membrane defect that results in
increased sensitivity to complement binding?
March hemoglobinuria
Paroxysmal cold hemoglobinuria
Paroxysmal nocturnal hemoglobinuria
Methemoglobinemia
Paroxysmal nocturnal hemoglobinuria
What membrane-associated protein in enterocytes transports iron from the
intestinal lumen into the enterocyte?
Transferrin
Ferroportin
DMT1
Ferrochelatase
DMT1
The majority of acquired aplastic anemia cases usually results from which of the
following? pregnancy
chloramphenicol exposure
radiation exposure
unknown cause
none of these
unknown cause
The anemia found in chronic renal failure is most likely caused by:
loss of erythropoietin synthesis
lack of cellular oxygen demand
defective iron absorption
destruction of red cells by uremic metabolites
loss of erythropoietin synthesis
Anemia of chronic inflammation can result from Increased hepcidin
Inappropriately decreased erythropoietin
Suppression of erythropoiesis by cytokines from activated macrophages and
lymphocytes
Impaired iron metabolism
All of these choices
,All of these choices
If a blood smear is too long, the problem can be resolved by:
Decreasing the angle of the pusher slide
Increasing the angle of the pusher slide
Using a larger drop of blood
Pushing the slide slower in smearing
Increasing the angle of the pusher slide
Blood is drawn to the 0.5 mark in an RBC diluting pipette. In five small squares of
the center square in a Neubauer hemocytometer, 210 cells counted. What is the
RBC count?
2.1 x 109/L
210 x 1012/L
0.21 x 1012/L
2.1 x 1012/L
2.1 x 1012/L
Which Plasmodium species is widespread in Malaysia, has RBCs with multiple
ring forms, has band-shaped early tro- phozoites, shows a 24-hour erythrocytic
cycle, and can cause severe disease and high parasitemia?
P. falciparum
P. vivax
P. knowlesi
P. malariae
more than one possible answer
none of these choices
P. knowlesi
Anemia associated with bone marrow infiltration an hyperproliferation by
nonerythroid cells:
aplastic anemia
Myelophthisic anemia
sideroblastic anemia
Thalassemia
Myelophthisic anemia
An elderly man with a 10-year history of chronic lymphocytic leukemia presented
with jaundice and fatigue that was attributed to a recent 3-gram drop in his
hemoglobin. Many spherocytes and polychromatophilic red cells were found on
his Wright's stained blood smear. Which type of immune hemolytic anemia is
most likely?
Idiopathic warm autoimmune hemolytic anemia
Secondary warm autoimmune hemolytic anemia
Primary cold hemagglutinin disease
Paroxysmal cold hemoglobinuria
Paroxysmal nocturnal hemoglobinuria
none of these choices
Secondary warm autoimmune hemolytic anemia
The CBC for a 57-year-old man had the following results. RBC 2.5 x 10^12/L, Hgb
8.5 g/dL, Hct 26.0%, MCV 118 fL, MCH 32 pg, MCHC 33%. Which tests would be
, best to order next?
Iron studies
Vitamin B12 and folic acid levels
Bone marrow examination
Intrinsic factor antibodies
None; normal result
Vitamin B12 and folic acid levels
Abetalipoproteinemia is characterized by mild anemia and numerous
_____________ on the peripheral blood smear.
Schistocyte
Acanthocytes
Echinocyte
Stomatocyte
None of these choices
Acanthocytes
What is the function of reduced glutathione (GSH) in the red blood cell?
Promotes Kreb's cycle activity
Maintains anion balance during the "chloride shift"
Neutralizes intracellular oxidants that accumulate
Prevents oxygen uptake by hemoglobin
Neutralizes intracellular oxidants that accumulate
Abnormal forms of erythrocytes seen in cases of myelophthisic anemia are:
Codocytes
Dacrocytes
Stomatocytes
Elliptocytes
Drepanocytes
none of these choices
Dacrocytes
Which of the following is a description of the structure of oxidized hemoglobin?
Hemoglobin carrying oxygen on heme; synonymous with oxygenated
hemoglobin
Hemoglobin with iron in the ferric state and not able to carry oxygen
Hemoglobin with iron in the ferric state so that carbon dioxide replaces oxygen in
the heme structure
Hemoglobin carrying carbon monoxide; hence oxidized refers to the single
oxygen
Hemoglobin with iron in the ferric state and not able to carry oxygen
Transfer of Iron from the enterocyte into the plasma is regulated by:
Transferrin
Ferroportin
Hephaestin
Hepcidin
Hepcidin
Which of the following tests yields results that are abnormal in DIC but are
usually within the reference interval or just slightly abnormal in TTP and HUS?
ANSWERS A+ GRADED .Buy Quality Materials!
Typical laboratory findings in TTP and HUS include:
Schistocytosis and thrombocytopenia
Anemia and reticulocytopenia
Reduced levels of lactate dehydrogenase and aspartate aminotransferase
Increased levels of free plasma hemoglobin and serum
more than one possible answer
none of these choices
Schistocytosis and thrombocytopenia
Which of the following is an acquired red cell membrane defect that results in
increased sensitivity to complement binding?
March hemoglobinuria
Paroxysmal cold hemoglobinuria
Paroxysmal nocturnal hemoglobinuria
Methemoglobinemia
Paroxysmal nocturnal hemoglobinuria
What membrane-associated protein in enterocytes transports iron from the
intestinal lumen into the enterocyte?
Transferrin
Ferroportin
DMT1
Ferrochelatase
DMT1
The majority of acquired aplastic anemia cases usually results from which of the
following? pregnancy
chloramphenicol exposure
radiation exposure
unknown cause
none of these
unknown cause
The anemia found in chronic renal failure is most likely caused by:
loss of erythropoietin synthesis
lack of cellular oxygen demand
defective iron absorption
destruction of red cells by uremic metabolites
loss of erythropoietin synthesis
Anemia of chronic inflammation can result from Increased hepcidin
Inappropriately decreased erythropoietin
Suppression of erythropoiesis by cytokines from activated macrophages and
lymphocytes
Impaired iron metabolism
All of these choices
,All of these choices
If a blood smear is too long, the problem can be resolved by:
Decreasing the angle of the pusher slide
Increasing the angle of the pusher slide
Using a larger drop of blood
Pushing the slide slower in smearing
Increasing the angle of the pusher slide
Blood is drawn to the 0.5 mark in an RBC diluting pipette. In five small squares of
the center square in a Neubauer hemocytometer, 210 cells counted. What is the
RBC count?
2.1 x 109/L
210 x 1012/L
0.21 x 1012/L
2.1 x 1012/L
2.1 x 1012/L
Which Plasmodium species is widespread in Malaysia, has RBCs with multiple
ring forms, has band-shaped early tro- phozoites, shows a 24-hour erythrocytic
cycle, and can cause severe disease and high parasitemia?
P. falciparum
P. vivax
P. knowlesi
P. malariae
more than one possible answer
none of these choices
P. knowlesi
Anemia associated with bone marrow infiltration an hyperproliferation by
nonerythroid cells:
aplastic anemia
Myelophthisic anemia
sideroblastic anemia
Thalassemia
Myelophthisic anemia
An elderly man with a 10-year history of chronic lymphocytic leukemia presented
with jaundice and fatigue that was attributed to a recent 3-gram drop in his
hemoglobin. Many spherocytes and polychromatophilic red cells were found on
his Wright's stained blood smear. Which type of immune hemolytic anemia is
most likely?
Idiopathic warm autoimmune hemolytic anemia
Secondary warm autoimmune hemolytic anemia
Primary cold hemagglutinin disease
Paroxysmal cold hemoglobinuria
Paroxysmal nocturnal hemoglobinuria
none of these choices
Secondary warm autoimmune hemolytic anemia
The CBC for a 57-year-old man had the following results. RBC 2.5 x 10^12/L, Hgb
8.5 g/dL, Hct 26.0%, MCV 118 fL, MCH 32 pg, MCHC 33%. Which tests would be
, best to order next?
Iron studies
Vitamin B12 and folic acid levels
Bone marrow examination
Intrinsic factor antibodies
None; normal result
Vitamin B12 and folic acid levels
Abetalipoproteinemia is characterized by mild anemia and numerous
_____________ on the peripheral blood smear.
Schistocyte
Acanthocytes
Echinocyte
Stomatocyte
None of these choices
Acanthocytes
What is the function of reduced glutathione (GSH) in the red blood cell?
Promotes Kreb's cycle activity
Maintains anion balance during the "chloride shift"
Neutralizes intracellular oxidants that accumulate
Prevents oxygen uptake by hemoglobin
Neutralizes intracellular oxidants that accumulate
Abnormal forms of erythrocytes seen in cases of myelophthisic anemia are:
Codocytes
Dacrocytes
Stomatocytes
Elliptocytes
Drepanocytes
none of these choices
Dacrocytes
Which of the following is a description of the structure of oxidized hemoglobin?
Hemoglobin carrying oxygen on heme; synonymous with oxygenated
hemoglobin
Hemoglobin with iron in the ferric state and not able to carry oxygen
Hemoglobin with iron in the ferric state so that carbon dioxide replaces oxygen in
the heme structure
Hemoglobin carrying carbon monoxide; hence oxidized refers to the single
oxygen
Hemoglobin with iron in the ferric state and not able to carry oxygen
Transfer of Iron from the enterocyte into the plasma is regulated by:
Transferrin
Ferroportin
Hephaestin
Hepcidin
Hepcidin
Which of the following tests yields results that are abnormal in DIC but are
usually within the reference interval or just slightly abnormal in TTP and HUS?
