HEMA BOC REVIEWER QUESTIONS AND ANSWERS A+
GRADED .Buy Quality Materials!
a patient with polycythemia vera who is treated by phlebotomy is most likely to
develop a deficiency of
iron -iron loss with loss of blood
the direct antiglobulin test is often positive in
acquired hemolytic anemia - positive DAT
the anemia of chronic infection is characterize by
decrease serum level- serum Fe levels low due to sequestration in macrophages and
hepatocyte
factors commonly involved in producing anemia in patients with chronic renal
disease include
inadequate erythropoiesis -
a 20 year old woman with sickle cell anemia whose usual. hemoglobin
concentration is 8g/dl (80 g/ L) develops fever, increase weakness and malaise.
the Hgb concentration is 4 g/dl (40g/L) and the reticulocyte count is 0.1% . The
most likely explanation for her clinical picture is
aplastic crisis - (sickle cell disease, effect on lab result)
the hypoproliferative red cell population in the bone marrow of uremic patients is
caused by
decreased levels of circulating erythropoietin
( bone marrow , how affected by uremia)
which of the following hypochromic anemias is usually associated with a normal
free erythrocyte protoporphyrin level?
thalassemia minor (FEP)
evidence indicates that the genetic defect in thalassemia usually result in
a quantitative deficiency in RNA resulting in decreased globin chain production
( mechanism of genetic abnormality in thalassemia reduce globin chain production
a 20 year -old African- American man has peripheral blood changes suggesting
thalassemia minor the quantitative hemoglobin A2 level is normal, but the hgb F
level is 5% ( ( normal is < 2%).This is most consistent with
delta- beta thalassemia minor Thalassemia with elevated Hgb F and normal Hgb A2
levels
anemia secondary to uremia characteristically is
normocytic,normochromic ( anemia related to uremia has normal size, normochromic
cells, it is the number of RBC that is decreased
which of the ff sets of laboratory findings is consistent with hemolytic anemia?
decreased erythrocyte survival; increased catabolism of heme
an enzyme deficiency associated with a moderate to sever hemolytic anemia after
the patient is exposed to certain drugs and characterized by red cell inclusions
formed by denatured Hgb is:
G-6-PD deficiency
Patient with A (-) type G-6-PD deficiency are least likely to have hemolytic
episodes in which of the ff. situations?
, spontaneously ( G-6-PD deficiency- hemolytic stimulus)
a pt has a congenital non spherocytic hemolytic anemia. After exposure to anti-
malarial drugs the patient experiences a severe hemolytic episode. this episode
is characterized by red cell inclusions caused by Hgb denaturation. Which of the
ff condition is most consistent with these findings?
G-6-PD deficiency ( anti - malarial drug)
laboratory test performed on a patient indicate macrocytosis, anemia, leukopenia
and thrombocytopenia. which of the ff. disorders is the pt most likelyto have
vitamin B 12 deficiency result in pernicious anemia pancytopenia, macrocytosis
the characteristic morphologic feature in folic acid deficiency
macrocytosis ( Folate deficiency- peripheral smear will show abnormally large RBC
the most likely cause of the macrocytosis that often accompanies anemia of
myelofibrosis is
folic acid deficiency ( myelofibrosis is often accompanied by folate deficiency which
causes macrocytic anemia
Megaloblastic asynchronous development in the bone marrow indicates which of
the ff?
impaired synthesis of DNA
which of the ff are found in association with megaloblastic anemia?
neutropenia and thrombocytopenia ( megaloblastic anemia laboratory results include
low platelet and neutrophil counts.
which of the ff. represents characteristic features of iron metabolism in patients
with anemia of a chronic disorder
decrease serum iron, decrease transferrin saturation and normal or decrease TIBC
a characteristic morphologic features i. hemoglobin C disease is
target cells
Thalassemia are characterized by
decrease rate of globin synthesis
a patient has the ff blood values
RBC 6.5 x 10
hgb 13
hct 39.0
mcv 65
MCH. 21.5
MCHC 33%
the results are compatible withb
Thalassemia minor
laboratory findings in hereditary spherocytosis
increase autohemolysis corrected by glucose
reticulocytosis
shortened erythrocyte survival
which of the ff types of polycytemia is severely burned pt most likely to have?
relative polycytemia associated with dehydration
Giant, vacuolated, multinucleated erythroid precursors are present in which of
the ff?
erythroleukemia
GRADED .Buy Quality Materials!
a patient with polycythemia vera who is treated by phlebotomy is most likely to
develop a deficiency of
iron -iron loss with loss of blood
the direct antiglobulin test is often positive in
acquired hemolytic anemia - positive DAT
the anemia of chronic infection is characterize by
decrease serum level- serum Fe levels low due to sequestration in macrophages and
hepatocyte
factors commonly involved in producing anemia in patients with chronic renal
disease include
inadequate erythropoiesis -
a 20 year old woman with sickle cell anemia whose usual. hemoglobin
concentration is 8g/dl (80 g/ L) develops fever, increase weakness and malaise.
the Hgb concentration is 4 g/dl (40g/L) and the reticulocyte count is 0.1% . The
most likely explanation for her clinical picture is
aplastic crisis - (sickle cell disease, effect on lab result)
the hypoproliferative red cell population in the bone marrow of uremic patients is
caused by
decreased levels of circulating erythropoietin
( bone marrow , how affected by uremia)
which of the following hypochromic anemias is usually associated with a normal
free erythrocyte protoporphyrin level?
thalassemia minor (FEP)
evidence indicates that the genetic defect in thalassemia usually result in
a quantitative deficiency in RNA resulting in decreased globin chain production
( mechanism of genetic abnormality in thalassemia reduce globin chain production
a 20 year -old African- American man has peripheral blood changes suggesting
thalassemia minor the quantitative hemoglobin A2 level is normal, but the hgb F
level is 5% ( ( normal is < 2%).This is most consistent with
delta- beta thalassemia minor Thalassemia with elevated Hgb F and normal Hgb A2
levels
anemia secondary to uremia characteristically is
normocytic,normochromic ( anemia related to uremia has normal size, normochromic
cells, it is the number of RBC that is decreased
which of the ff sets of laboratory findings is consistent with hemolytic anemia?
decreased erythrocyte survival; increased catabolism of heme
an enzyme deficiency associated with a moderate to sever hemolytic anemia after
the patient is exposed to certain drugs and characterized by red cell inclusions
formed by denatured Hgb is:
G-6-PD deficiency
Patient with A (-) type G-6-PD deficiency are least likely to have hemolytic
episodes in which of the ff. situations?
, spontaneously ( G-6-PD deficiency- hemolytic stimulus)
a pt has a congenital non spherocytic hemolytic anemia. After exposure to anti-
malarial drugs the patient experiences a severe hemolytic episode. this episode
is characterized by red cell inclusions caused by Hgb denaturation. Which of the
ff condition is most consistent with these findings?
G-6-PD deficiency ( anti - malarial drug)
laboratory test performed on a patient indicate macrocytosis, anemia, leukopenia
and thrombocytopenia. which of the ff. disorders is the pt most likelyto have
vitamin B 12 deficiency result in pernicious anemia pancytopenia, macrocytosis
the characteristic morphologic feature in folic acid deficiency
macrocytosis ( Folate deficiency- peripheral smear will show abnormally large RBC
the most likely cause of the macrocytosis that often accompanies anemia of
myelofibrosis is
folic acid deficiency ( myelofibrosis is often accompanied by folate deficiency which
causes macrocytic anemia
Megaloblastic asynchronous development in the bone marrow indicates which of
the ff?
impaired synthesis of DNA
which of the ff are found in association with megaloblastic anemia?
neutropenia and thrombocytopenia ( megaloblastic anemia laboratory results include
low platelet and neutrophil counts.
which of the ff. represents characteristic features of iron metabolism in patients
with anemia of a chronic disorder
decrease serum iron, decrease transferrin saturation and normal or decrease TIBC
a characteristic morphologic features i. hemoglobin C disease is
target cells
Thalassemia are characterized by
decrease rate of globin synthesis
a patient has the ff blood values
RBC 6.5 x 10
hgb 13
hct 39.0
mcv 65
MCH. 21.5
MCHC 33%
the results are compatible withb
Thalassemia minor
laboratory findings in hereditary spherocytosis
increase autohemolysis corrected by glucose
reticulocytosis
shortened erythrocyte survival
which of the ff types of polycytemia is severely burned pt most likely to have?
relative polycytemia associated with dehydration
Giant, vacuolated, multinucleated erythroid precursors are present in which of
the ff?
erythroleukemia
