PULMONARY NEOPLASMS QUESTIONS AND ANSWERS A+
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Who should be screened for lung cancer?
-age 50-77
-smoked within the past 15 yrs
-hx of 20 packs or more a yr
-should not screen in pt that have a health problem that limits life expectancy or the
ability to undergo lung surgery
risk factors for bronchogenic carcinoma
-smoking (including second hand)
-radon
-asbestos
What is the most common type of NSCLC
adenocarcinoma
What to know about adenocarcinoma
-mostly due to smoking but is also the most common type of lung cancer in non-
smokers
-more prevalent in the upper lobes than lower lobes
-more common in the periphery
-arises from mucous glands or any epithelial cell within or distal to terminal bronchioles
-often metastasizes to the brain (but can also go to bone liver or adrenals)
-generally more treatable than other subtypes of NSCLC
dx criteria for adenocarcinoma
requires 1 on the following features:
-glandular differentiation
-mucin production
-expression of pneumocyte markers
-acinar pattern seen on histology
what to know about SCC of NSCLC
-smoking
-comes from squamous cells in bronchial epithelium
-centrally located
-likely to cavitate (will see mass with a central hollow area)
-can cause bronchial constriction leads to atelectasis and post obstructive PNA
-more aggressive than adenocarcinoma
what to know about large cell carcinoma
-undifferentiated cancer with large cells
-no evidence of keritinization or gland formation
-can be central or peripheral
-most aggressive NSCLC
histology findings for SCC
-large cells containing keratin and intercellular bridges
what to know about small cell carcinomas
GRADED .Buy Quality Materials!
Who should be screened for lung cancer?
-age 50-77
-smoked within the past 15 yrs
-hx of 20 packs or more a yr
-should not screen in pt that have a health problem that limits life expectancy or the
ability to undergo lung surgery
risk factors for bronchogenic carcinoma
-smoking (including second hand)
-radon
-asbestos
What is the most common type of NSCLC
adenocarcinoma
What to know about adenocarcinoma
-mostly due to smoking but is also the most common type of lung cancer in non-
smokers
-more prevalent in the upper lobes than lower lobes
-more common in the periphery
-arises from mucous glands or any epithelial cell within or distal to terminal bronchioles
-often metastasizes to the brain (but can also go to bone liver or adrenals)
-generally more treatable than other subtypes of NSCLC
dx criteria for adenocarcinoma
requires 1 on the following features:
-glandular differentiation
-mucin production
-expression of pneumocyte markers
-acinar pattern seen on histology
what to know about SCC of NSCLC
-smoking
-comes from squamous cells in bronchial epithelium
-centrally located
-likely to cavitate (will see mass with a central hollow area)
-can cause bronchial constriction leads to atelectasis and post obstructive PNA
-more aggressive than adenocarcinoma
what to know about large cell carcinoma
-undifferentiated cancer with large cells
-no evidence of keritinization or gland formation
-can be central or peripheral
-most aggressive NSCLC
histology findings for SCC
-large cells containing keratin and intercellular bridges
what to know about small cell carcinomas
