PULMONARY NEOPLASMS QUESTIONS AND ANSWERS A+
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Neoplasms: can be.....
•Benign
•In-situ neoplasms-in one tissue
•Malignant neoplasms - cancer
•Neoplasms of uncertain behavior
For this class...an un-checked growth, mass =
tumor
What is the #1 cause of cancer deaths in men and women?
lung cancer
How many people are affected by cancer over 60?
81%
Screening for lung cancer photo:
What are some of the causes of lung cancer?
•90% due to smoking
•Radon and asbestos 5-10%
•Air pollution 1-2%
How many types of non-small-cell are there?
four
What percent of lung cancers are non-small-cell?
85%
What is some of the characteristics of non-small-cell cancer?
Relatively slow growing, therefore amendable to surgical resection, especially stages 1-
2
What is the most common type of bronchogenic carcinoma at 40%?
Adenocarcinoma
How would a patient present with Adenocarcinoma?
incidental finding, non-smoker, small peripheral lesion, clubbing
Squamous cell carcinoma makes up what percentage of non-small-cell cancers?
25-35%
A person described as, "smoker with hemoptysis, large central solitary tumor" on
physical exam would be consistent with what type of cancer?
Squamous cell carcinoma
Large cell lung cancer makes up what percentage of cases?
5-10%
What are some characteristics and s/s of large cell lung cancer?
associated with smoking, found throughout the lungs, fast doubling rates, responds to
surgery
What form of non-small-cell cancer has the lowest case rate?
Carcinoid tumor: at 1-2%
Low grade malignancy of neuroendocrine cells is a characteristic of what lung
cancer?
, Carcinoid tumor
Non-small cell can be treated what what?
surgery
Stage 1-2 non-small cancer:
surgery
stage 3 non-small cancer:
Chemo then surgery
Stage 4 non-small cancer:
palliative
Small Cell (Oat Cell) cancer makes up what percentage of cases?
•15% (small % with big problems)
What cancer presents as: "Highly aggressive, rapidly growing, central lesion,
found in smokers"
Small Cell (Oat Cell)
What percent of Small Cell (Oat Cell) is metastatic at time of diagnosis?
80%
Paraneoplastic syndrome:
•SIADH - hyponatremia
•ACTH - Cushing's
•Parathyroid hormone - hypercalcemia
What is Lambert-Eaton myasthenic syndrome?
•characterized by muscle weakness of the limbs caused by ACTH/ADH
What is the treatment for Small Cell (Oat Cell)?
palliative chemotherapy-->make them comfortable and try to slow down progression
True or false: There is a poor prognosis - 5-year survival rate ~ 10%- in small cell
lung cancer
True
Lung cancer - review: small cell
•*Small cell ~ 15%
•BIG ISSUES
•Central/mediastinal location
•Aggressive
•Early mets
•Poor prognosis
•Primary treatment:
•palliative chemo
•* associated with smoking
Lung cancer - review: Non-small Cell
•Non-small Cell ~ 85%
•Adenocarcinoma ~ 40%
•Peripheral location
•Often occur with underlying lung disease
•*Squamous Cell ~ 25-35%
•*Large Cell ~ 10%
•Carcinoid ~ 1-2%
•Primary treatment:
GRADED .Buy Quality Materials!
Neoplasms: can be.....
•Benign
•In-situ neoplasms-in one tissue
•Malignant neoplasms - cancer
•Neoplasms of uncertain behavior
For this class...an un-checked growth, mass =
tumor
What is the #1 cause of cancer deaths in men and women?
lung cancer
How many people are affected by cancer over 60?
81%
Screening for lung cancer photo:
What are some of the causes of lung cancer?
•90% due to smoking
•Radon and asbestos 5-10%
•Air pollution 1-2%
How many types of non-small-cell are there?
four
What percent of lung cancers are non-small-cell?
85%
What is some of the characteristics of non-small-cell cancer?
Relatively slow growing, therefore amendable to surgical resection, especially stages 1-
2
What is the most common type of bronchogenic carcinoma at 40%?
Adenocarcinoma
How would a patient present with Adenocarcinoma?
incidental finding, non-smoker, small peripheral lesion, clubbing
Squamous cell carcinoma makes up what percentage of non-small-cell cancers?
25-35%
A person described as, "smoker with hemoptysis, large central solitary tumor" on
physical exam would be consistent with what type of cancer?
Squamous cell carcinoma
Large cell lung cancer makes up what percentage of cases?
5-10%
What are some characteristics and s/s of large cell lung cancer?
associated with smoking, found throughout the lungs, fast doubling rates, responds to
surgery
What form of non-small-cell cancer has the lowest case rate?
Carcinoid tumor: at 1-2%
Low grade malignancy of neuroendocrine cells is a characteristic of what lung
cancer?
, Carcinoid tumor
Non-small cell can be treated what what?
surgery
Stage 1-2 non-small cancer:
surgery
stage 3 non-small cancer:
Chemo then surgery
Stage 4 non-small cancer:
palliative
Small Cell (Oat Cell) cancer makes up what percentage of cases?
•15% (small % with big problems)
What cancer presents as: "Highly aggressive, rapidly growing, central lesion,
found in smokers"
Small Cell (Oat Cell)
What percent of Small Cell (Oat Cell) is metastatic at time of diagnosis?
80%
Paraneoplastic syndrome:
•SIADH - hyponatremia
•ACTH - Cushing's
•Parathyroid hormone - hypercalcemia
What is Lambert-Eaton myasthenic syndrome?
•characterized by muscle weakness of the limbs caused by ACTH/ADH
What is the treatment for Small Cell (Oat Cell)?
palliative chemotherapy-->make them comfortable and try to slow down progression
True or false: There is a poor prognosis - 5-year survival rate ~ 10%- in small cell
lung cancer
True
Lung cancer - review: small cell
•*Small cell ~ 15%
•BIG ISSUES
•Central/mediastinal location
•Aggressive
•Early mets
•Poor prognosis
•Primary treatment:
•palliative chemo
•* associated with smoking
Lung cancer - review: Non-small Cell
•Non-small Cell ~ 85%
•Adenocarcinoma ~ 40%
•Peripheral location
•Often occur with underlying lung disease
•*Squamous Cell ~ 25-35%
•*Large Cell ~ 10%
•Carcinoid ~ 1-2%
•Primary treatment:
