NURS 1060 - EXAM 1 QUESTIONS AND ANSWERS VERIFIED
list 4 precautions for a sustained-release medication
don't crush, break, or chew
don't take more than recommended amount
food promotes absorption & dissolution
don't take recreational drugs/ drink alcohol
more lipid soluble
non-ionized
more water soluble
ionized
moves readily through membranes
non-ionized
dissolves readily in body fluids
ionized
has an electrical charge
ionized
state of an acid drug in the stomach
non-ionized
state of a basic drug in the intestinal tract
non-ionized
the stomach provides a ________ area for absorption than does the intestine
smaller
, list three factors which affect the amount of surface area available for absorption
in the intestine
pH
transport protein
blood flow
list two factors which will delay stomach emptying
fatty foods
pylori sphincter
laying on left side
When a tetracycline drug and an antacid are administered concurrently, what type
of drug interaction occurs?
Formation of an insoluble compound - inactive absorption
Drug absorption is _____________ when a drug complexes with food to form an
insoluble complex.
slower/ delayed
The amount of drug absorbed when drugs move rapidly through the G.I. tract
is_________ than when the movement is slower.
Less
Phase I - clinical research
healthy human volunteers
tests: metabolism, pharmacokinetics, & biologic effects
Phase II - clinical research
list 4 precautions for a sustained-release medication
don't crush, break, or chew
don't take more than recommended amount
food promotes absorption & dissolution
don't take recreational drugs/ drink alcohol
more lipid soluble
non-ionized
more water soluble
ionized
moves readily through membranes
non-ionized
dissolves readily in body fluids
ionized
has an electrical charge
ionized
state of an acid drug in the stomach
non-ionized
state of a basic drug in the intestinal tract
non-ionized
the stomach provides a ________ area for absorption than does the intestine
smaller
, list three factors which affect the amount of surface area available for absorption
in the intestine
pH
transport protein
blood flow
list two factors which will delay stomach emptying
fatty foods
pylori sphincter
laying on left side
When a tetracycline drug and an antacid are administered concurrently, what type
of drug interaction occurs?
Formation of an insoluble compound - inactive absorption
Drug absorption is _____________ when a drug complexes with food to form an
insoluble complex.
slower/ delayed
The amount of drug absorbed when drugs move rapidly through the G.I. tract
is_________ than when the movement is slower.
Less
Phase I - clinical research
healthy human volunteers
tests: metabolism, pharmacokinetics, & biologic effects
Phase II - clinical research
