NURS 1060: DRUG INTERACTION, ADVERSE REACTIONS, AND
ERRORS EXAM QUESTIONS AND ANSWERS WITH COMPLETE
SOLUTIONS GRADED A++
what is the concept of safety?
Minimizing risk of human harm through both system effectiveness and individual
performance
what is the concept of culture?
patterns of behavior and thinking that people living in social groups learn, develop, and
share.
what is the concept of diversity?
the array of differences among individuals, groups, and communities
what are intensification of effects?
increased therapeutic and adverse effects
what are reduction of effects of drug to drug?
reduced therapeutic and adverse effects
what are consequences of drug-drug interactions?
can create and unknown chemical when mixing two drugs that will be given parenteral
what are examples of drug-drug interactions?
creation of unique or unknown response (alcohol with barbiturate can be lethal)
what do you do to stop direct chemical or physical interaction?
, never combine drugs in same container or syringe without establishing compatibility
-check the drug compatibility chart or in the electronic clinical support system
what are examples of altered absorption?
-drugs that depress peristalsis
-drugs that induce vomiting
what are example of altered distribution?
competition for protein binding
what are examples of altered metabolism?
Phenobarbital is an inducing agent that increases the synthesis/production of hepatic
cytochrome P450 (CYP) enzymes responsible for the metabolism of many drugs
what are examples of altered renal exxretion?
drugs can alter filtration, reabsorption, active secretion
taking phenobarbital can?
increase the metabolism of other drugs
what are isozymes?
2 or more enzymes that have a different chemical structure but the same function
what does intestinal epithelium affect?
absorption
what is the effect on the placenta?
affects drug export from placental cells to maternal blood
what is the effect on the blood brain barrier?
affects drug export from cells of brain capillaries into the blood
what is the effect on the liver?
ERRORS EXAM QUESTIONS AND ANSWERS WITH COMPLETE
SOLUTIONS GRADED A++
what is the concept of safety?
Minimizing risk of human harm through both system effectiveness and individual
performance
what is the concept of culture?
patterns of behavior and thinking that people living in social groups learn, develop, and
share.
what is the concept of diversity?
the array of differences among individuals, groups, and communities
what are intensification of effects?
increased therapeutic and adverse effects
what are reduction of effects of drug to drug?
reduced therapeutic and adverse effects
what are consequences of drug-drug interactions?
can create and unknown chemical when mixing two drugs that will be given parenteral
what are examples of drug-drug interactions?
creation of unique or unknown response (alcohol with barbiturate can be lethal)
what do you do to stop direct chemical or physical interaction?
, never combine drugs in same container or syringe without establishing compatibility
-check the drug compatibility chart or in the electronic clinical support system
what are examples of altered absorption?
-drugs that depress peristalsis
-drugs that induce vomiting
what are example of altered distribution?
competition for protein binding
what are examples of altered metabolism?
Phenobarbital is an inducing agent that increases the synthesis/production of hepatic
cytochrome P450 (CYP) enzymes responsible for the metabolism of many drugs
what are examples of altered renal exxretion?
drugs can alter filtration, reabsorption, active secretion
taking phenobarbital can?
increase the metabolism of other drugs
what are isozymes?
2 or more enzymes that have a different chemical structure but the same function
what does intestinal epithelium affect?
absorption
what is the effect on the placenta?
affects drug export from placental cells to maternal blood
what is the effect on the blood brain barrier?
affects drug export from cells of brain capillaries into the blood
what is the effect on the liver?
