PULMONARY NEOPLASMS QUESTIONS AND ANSWERS A+
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A well-differentiated neuroendocrine tumors (NETs) arising in the lung >> leading
to excess serotonin, histamine and bradykinin best describes?
carcinoid tumor
A carcinoid tumor leads to excess of which neuroendocrine
hormones/transmitters?
Serotonin, Histamine, Bradykinin
What is the most frequently involved organ for a neuroendocrine tumor?
1st is GI tract 2nd is lungs
Low-grade neoplasms arising from endocrine cells that rarely metastasize and
are slow growing best describes?
Carcinoid tumors
T/F smoking is not a risk factor for carcinoid tumors?
True
What is the most common site that a neuroendocrine tumor will metastasize to?
Liver, Pt is usually asymptomatic until the tumor reaches the liver.
What is the hallmark sign for carcinoid syndrome?
-Flushing (high bradykinin & histamine)
-Diarrhea (High serotonin)
-Wheezing and HYPOtension
Most lung carcinoids tumors arise in which part of the airway?
Proximal airways
What are some of the most common symptoms of bronchial carcinoid tumors?
Hemoptysis, cough, focal wheezing, and recurrent pneumonia
What will a fiberoptic bronchoscopy finding of carcinoid tumor look like?
Pink/purple well vascularized tumor in the central airway.
66 year old male pt presents to the pulmonologist for c/o coughing a/w
hemoptysis. Upon auscultation you hear wheezing. Pt denies a PHx of smoking
or working in an environment that could have exposed him to any carcinogens.
On PE you note the pt has some erythematous skin. The pt also states he has
been having constant diarrhea. His BP is 100/72. You order a bronchoscopy and it
reveals pinkish purple tumor that is well vascularized. What would be the next
step to treat this pt?
A.)Chemotherapy/radiation
B.)Surveillance
C.)Surgical excision
D.)Lung transplant
C.)Surgical excision
Pt is diagnosed with Carcinoid tumor... Radiation/chemo is resistant
Which of the following non-small cell lung cancers has the lowest association
with smoking?
, A.)Small (oat) cell
B.)Large cell
C.)Adenocarcinoma
D.)Squamous cell
C.)Adenocarcinoma
A new onset of cough from a former smoker should raise suspicion from which
lung cancers due to their tendency to involve the central airways?
Small cell carcinoma and Non small cell squamous
What is the definitive diagnosis to differentiate SCLC and NSCLC?
Tissue biopsy
In which lung cancer will you see a more rapidly progressive symptoms and the
presence of para neoplastic syndrome symptoms like SIADH (HYPOnatremia )
and superior vena cava syndrome?
A.)Large Cell LC
B.)Adenocarcinoma
C.)Squamous cell LC
D.)Small cell lung cancer
d.)Small cell LC
Most aggressive an deadliest
When determining the growth pattern of an identified abnormality what do we
want to do in order to determine it's progression?
We want to obtain and review any prior chest imaging studies to compare it to see its
evolution.
Which is best describes the most aggressive, centrally located, rapidly growing
and usually already metastasized at the time of Dx? How do we treat these pts?
Small cell LC
We Tx these pt with Chemo +/- Radiation bc by the time of Dx, the cancer has spread
extensively and excision would be removal of too much tissue.
Limited SCLC is defined to be confined to what parts of the body?
Just the chest + Supraclavicular nodes (not cervical or axillary)
Extensive SCLC is defined to be metastasized to what parts of the body?
Past the chest and Supraclavicular nodes
Whats the MC type of NSCLC?
Adenocarcinoma
T/F Adenocarcinoma is more closely associated with Non-smokers and women
than other lung cancers?
TRUE BUT still over 75% of pt are found to be a previous smoker OR exposed to
asbestos.
Where is NSCLC-Adenocarcinoma usually located?
The periphery
Where is NSCLC-squamous cell located?
Centrally
Which of the following is the MC type of NSCLC type?
A.)Small
B.)Squamous
GRADED .Buy Quality Materials!
A well-differentiated neuroendocrine tumors (NETs) arising in the lung >> leading
to excess serotonin, histamine and bradykinin best describes?
carcinoid tumor
A carcinoid tumor leads to excess of which neuroendocrine
hormones/transmitters?
Serotonin, Histamine, Bradykinin
What is the most frequently involved organ for a neuroendocrine tumor?
1st is GI tract 2nd is lungs
Low-grade neoplasms arising from endocrine cells that rarely metastasize and
are slow growing best describes?
Carcinoid tumors
T/F smoking is not a risk factor for carcinoid tumors?
True
What is the most common site that a neuroendocrine tumor will metastasize to?
Liver, Pt is usually asymptomatic until the tumor reaches the liver.
What is the hallmark sign for carcinoid syndrome?
-Flushing (high bradykinin & histamine)
-Diarrhea (High serotonin)
-Wheezing and HYPOtension
Most lung carcinoids tumors arise in which part of the airway?
Proximal airways
What are some of the most common symptoms of bronchial carcinoid tumors?
Hemoptysis, cough, focal wheezing, and recurrent pneumonia
What will a fiberoptic bronchoscopy finding of carcinoid tumor look like?
Pink/purple well vascularized tumor in the central airway.
66 year old male pt presents to the pulmonologist for c/o coughing a/w
hemoptysis. Upon auscultation you hear wheezing. Pt denies a PHx of smoking
or working in an environment that could have exposed him to any carcinogens.
On PE you note the pt has some erythematous skin. The pt also states he has
been having constant diarrhea. His BP is 100/72. You order a bronchoscopy and it
reveals pinkish purple tumor that is well vascularized. What would be the next
step to treat this pt?
A.)Chemotherapy/radiation
B.)Surveillance
C.)Surgical excision
D.)Lung transplant
C.)Surgical excision
Pt is diagnosed with Carcinoid tumor... Radiation/chemo is resistant
Which of the following non-small cell lung cancers has the lowest association
with smoking?
, A.)Small (oat) cell
B.)Large cell
C.)Adenocarcinoma
D.)Squamous cell
C.)Adenocarcinoma
A new onset of cough from a former smoker should raise suspicion from which
lung cancers due to their tendency to involve the central airways?
Small cell carcinoma and Non small cell squamous
What is the definitive diagnosis to differentiate SCLC and NSCLC?
Tissue biopsy
In which lung cancer will you see a more rapidly progressive symptoms and the
presence of para neoplastic syndrome symptoms like SIADH (HYPOnatremia )
and superior vena cava syndrome?
A.)Large Cell LC
B.)Adenocarcinoma
C.)Squamous cell LC
D.)Small cell lung cancer
d.)Small cell LC
Most aggressive an deadliest
When determining the growth pattern of an identified abnormality what do we
want to do in order to determine it's progression?
We want to obtain and review any prior chest imaging studies to compare it to see its
evolution.
Which is best describes the most aggressive, centrally located, rapidly growing
and usually already metastasized at the time of Dx? How do we treat these pts?
Small cell LC
We Tx these pt with Chemo +/- Radiation bc by the time of Dx, the cancer has spread
extensively and excision would be removal of too much tissue.
Limited SCLC is defined to be confined to what parts of the body?
Just the chest + Supraclavicular nodes (not cervical or axillary)
Extensive SCLC is defined to be metastasized to what parts of the body?
Past the chest and Supraclavicular nodes
Whats the MC type of NSCLC?
Adenocarcinoma
T/F Adenocarcinoma is more closely associated with Non-smokers and women
than other lung cancers?
TRUE BUT still over 75% of pt are found to be a previous smoker OR exposed to
asbestos.
Where is NSCLC-Adenocarcinoma usually located?
The periphery
Where is NSCLC-squamous cell located?
Centrally
Which of the following is the MC type of NSCLC type?
A.)Small
B.)Squamous
