Pathophysiology Expected Questions and Answers
() (Verified Answers)- Chamberlain
1. Which of the following are considered the " first responders " of the innate
immune system ? - CORRECT ANSWER Neutrophils
2. Allergic contact dermatitis is an example of hypersensitivity reaction -
CORRECT ANSWER Type 4
3. Hives ( urticaria ) are an example of a : - CORRECT ANSWER Type 1
hypersensitivity reaction
4. Which of the assessment findings would be expected with urticaria ? -
CORRECT ANSWER Eosinophilia
5. Underlying pathology for hay fever ? - CORRECT ANSWER Mast cell
degranulation
6. Chronic granulomatous disease of Childhood
7. DiGeorge Syndrome
8. Job Sundrome
9. Common Variable Immunodeficiency
10. Familial Mediterranean fever - CORRECT ANSWER Primary
Immunodeficiencies
11. HIV
12. Pneumocystis Carinii
13. Pneumonia
14. Sinus Infection
15. Lung Cancer - CORRECT ANSWER Secondary Immunodeficiencies
16. Which CD4 count should be prescribed in HIV treatment Regimen ? -
CORRECT ANSWER Under 500
17. Before any invasive procedure , what should be administered to Immune -
Compromised individuals ? - CORRECT ANSWER Prophylactic antimicrobial
drugs
18. Immunodeficiency puts individuals most at risk for which 2 conditions ? -
CORRECT ANSWER Cancer and Opportunistic infections
,19. Treatment option for HIV ? - CORRECT ANSWER Highly active antiretroviral
therapy (HAART)
20. Which of the following assessment finding support a dx of Rheumatoid Arthritis ?
- CORRECT ANSWER Swollen metacarpophalangeal joints
21. T - cells , B - cells and autoantibodies can be involved in autoimmune diseases -
CORRECT ANSWER True
22. Best describes the symptoms of Systemic Lupus Erythematosus ( SLE ) -
CORRECT ANSWER Tissue inflammation , vasculitis , rash , tissue
inflammation
23. The process where a normal cell becomes a cancer cell - CORRECT ANSWER
Cell transformation
24. A common event during Cellular reproduction resulting in the Constant
occurrence of isolated Cancer cells - CORRECT ANSWER Cell transformation
25. An immature , undifferentiated ( generic ) cell that is capable of infinite cellular
division when stimulated - CORRECT ANSWER Stem cell
26. the process whereby the stem cell undergoes the process of cell division ( 24
hour cycle ) average - CORRECT ANSWER Cell cycle
27. Anaphylaxis is what type of hypersensitivity reaction? - CORRECT ANSWER
type 1
28. Type 2 ( Cytotoxic ) hypersensitivity reactions are mediated by : - CORRECT
ANSWER IgG or IgM
29. Damage occurs with ABO incompatibility because : - CORRECT ANSWER
Complement damages RBC membrane causing cell lysis
30. The diagnosis for an individual who presents to the office with sudden swollen
lips and eyes , shortness of breath and throat tightness after a bee sting is : -
CORRECT ANSWER Anaphylaxis
31. An example of a primary immunodeficiency is : - CORRECT ANSWER Chronic
Granulomatous Disease
32. a predominant cause of secondary immune deficiencies worldwide - CORRECT
ANSWER Malnutrition
33. Which of the following is an autoimmune disease ? - CORRECT ANSWER
Systemic Lupus Erythematosus ( SLE ) .
, 34. An example of a secondary immunodeficiency is - CORRECT ANSWER
Pneumocystis Carinii
35. Are less common and occur due to a defect on the development of the immune
system - CORRECT ANSWER primary immunodeficiency
36. A patient with human immunodeficiency virus ( HIV ) was admitted to the acute
care facility with difficulty breathing . He is diagnosed with Pneumocytis carinii .
Pneumocystis carinii an example of : - CORRECT ANSWER A secondary
immune disease
37. Sinusitis is considered a primary immunodeficiency - CORRECT ANSWER
False
38. Which of the following findings can be used to diagnose Systemic Lupus
Erythematosus ( SLE ) ? - CORRECT ANSWER Facial rash confined to the
cheeks
39. The major immune system change associated with Sjogren's Syndrome is : -
CORRECT ANSWER Autoantibodies and auto - reactive T - cells against
apoptotic cells
40. Which of the following can depress a person's normal immune function ? -
CORRECT ANSWER Psychological Stress
41. A renal disease most often associated with autoimmunity is : - CORRECT
ANSWER Glomerulonephritis
42. Which of the following assessment findings would support a diagnosis of
Rheumatoid Arthritis ( RA ) ? - CORRECT ANSWER Swollen
metacarpophalangeal joints
43. The following immune components can be involved in autoimmune diseases : T -
Cells , B - cells and autoantibodies . - CORRECT ANSWER True
44. The presenting signs and symptoms of an autoimmune disease is similar across
all autoimmune diseases - CORRECT ANSWER False
45. Which of the following indices measures the average size of red blood cells ? -
CORRECT ANSWER Mean Corpuscular Volume ( MCV ) .
46. Anemia can be caused from which of the following ? ( Select all that apply . ) -
CORRECT ANSWER Impaired red blood cell production, Increased red blood
cell destruction, Excessive blood loss