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Schizophrenia (negative symptoms)
The 5 A's:
Anhedonia
Alogia
Avolision
Affect
Apathetic
Alogia
A decrease in speech or speech content; a symptom of schizophrenia. Also known as
poverty of speech.
Avolition
a symptom of schizophrenia marked by apathy and an inability to start or complete a
course of action
Affect
Appearance of observable emotions
Apathetic
showing or feeling no interest, enthusiasm, or concern
Anhedonia
Inability to experience pleasure, associated with some mood and schizophrenic
disorders.
Schizophrenia (positive symptoms)
hallucinations, delusions, disorganized speech, disorganized behavior
Hallucinations can be ?
any of the 5 senses. Auditory, tactile, visual, taste, olfactory
Delusions
Fixed, false beliefs that are discordant with reality and not shared by one's culture, but
are maintained in spite of strong evidence to the contrary.
delusions of grandeur
A false belief that one is a famous person or a powerful or important person who has
some great knowledge, ability, or authority.
paranoid delusions
involve the false belief that other people or agencies are plotting to harm the person
persecutory delusions
beliefs of being targeted by others - people are going to hurt me
Religiosity Delusions
obsessed with religious beliefs
Alterations in speech
*flight of ideas
*neologisms
*echolalia
, *clang association
*word salad
Echolalia
The uncontrollable and immediate repetition of words spoken by another person
clang association
The meaningless rhyming of words, often in a forceful manner.
Word Salad
jumble of incoherent speech as sometimes heard in schizophrenia
flight of ideas
symptom of mania that involves an abruptly switching in conversation from one topic to
another
neologism
a new word, expression, or usage; the creation or use of new words or senses
4 phases of schizophrenia
Phase I - Premorbid phase
Phase II - Prodromal
Phase III - Schizophrenia
Phase IV - Residual
premorbid phase of schizophrenia
quiet, passive, introverted children; no close friends, no dates, no sports; shy
and withdrawn
Prodromal phase of schizophrenia
can last months to years; more withdrawn, functional impairments, sleep
disturbances starts, anxiety, irritable; *provide early interventions to avoid psychosis
Schizophrenia phase
psychotic break, MALES more than females, generally 18/19
residual phase of schizophrenia
a return to prodromal-like levels after psychotic break
2 types of schizophrenic meds
typical - 1st generation. also called antipsychotics/neuroleptics
Atypical - 2nd or 3rd generation
Typical Antipsychotics
only take care of the positive symptoms (delusions, hallucinations, etc.)
Haldol
haloperidol, typical antipsychotic
*long acting IM to aid in compliance (contraindicated w/ QT prolonged drugs)
Thorazine
Chlorpromazine
Prolixin
fluphenazine
long acting IM to aid in compliance
Atypical meds work on?
dopamine and serotonin (aka positive AND negative symptoms)
Clozaril (Clozapine)