QUESTIONS AND ANSWERS WITH COMPLETE
SOLUTIONS
(?) agonist: drug that stimulates the (?) receptors of the sympathetic nervous
system, either directly (by reacting with receptor sites) or indirectly (by
increasing norepinephrine levels)
adrenergic agonist
adrenergic receptors
(?) agonist: drug that specifically stimulates the alpha-receptors within the
sympathetic nervous system, causing body responses seen when the alpha-
receptors are stimulated
alpha-agonist
(?) agonist: drug that specifically stimulates the beta-receptors within the
sympathetic nervous system, causing body responses seen when the beta-
receptors are stimulated
beta-agonist
(?): drug that mimics the sympathetic nervous system (SNS) with the signs and
symptoms seen when the SNS is stimulated
sympathomimetic
Dopamine and norepinephrine are what class?
ALPHA- AND BETA-ADRENERGIC AGONISTS
,phenylephrine is what class?
ALPHA-SELECTIVE ADRENERGIC AGONISTS
albuterol and formoterol are what class?
BETA-SELECTIVE ADRENERGIC AGONISTS
An (?) agonist is also called a sympathomimetic drug because it mimics the
effects of the sympathetic nervous system (SNS).
adrenergic agonist
The therapeutic and adverse effects associated with these drugs are related to
their stimulation of adrenergic (?).
receptor sites.
That stimulation can be either (?) by occupation of the adrenergic receptor,
or (?) by modulation of the release of neurotransmitters from the axon.
That stimulation can be either direct, by occupation of the adrenergic receptor, or
indirect by modulation of the release of neurotransmitters from the axon.
Adrenergic agonists also can affect both the alpha- and beta-receptors, or they
can act at (?) sites.
specific receptor
Considerations for adrenergic agonist
Older patients commonly experience the adverse CNS, CV, GI, and respiratory
effects associated with these drugs. Because older patients often have (?) or (?)
impairment, they are also more likely to have a toxic level of the drug related to
changes in (?) and (?). Older patients may need to be started on lower doses of
, the drugs and should be monitored closely for potentially serious arrhythmias or
blood pressure changes.
They also should be cautioned about the use of OTC drugs and complementary
therapies that could increase drug effects and cause serious adverse reactions.
renal or hepatic
metabolism and excretion.
Drugs that are generally sympathomimetic are called (?) (stimulate alpha-
receptors) and (?) (stimulate beta-receptors).
alpha-agonists
beta-agonists
(?) stimulate all of the adrenergic receptors; that is, they affect both alpha- and
beta-receptors
General adrenergic agonists
Agents that affect both alpha- and beta-receptor sites
include dobutamine (generic), dopamine (generic), ephedrine (Akovaz,
Corphedra, Emerphed), epinephrine (Adrenalin, Adrenaclick, Auvi-Q, Epipen,
Primatene Mist, Symjepi), and norepinephrine (Levophed). Some of these drugs
are naturally occurring catecholamines.
"ine" s
The effects of the sympathomimetic drugs are mediated by the (?) receptors in
target organs: Heart rate (?) with increased myocardial contractility; bronchi (?)
and respirations (?) blood vessels (?) causing an increase in blood pressure;
intraocular pressure (?); glycogenolysis (breakdown of glucose stores so that the