2024 newest Exam 3|NUR 611|Maryville NURS Which of the following is true regarding renal
611 Exam 3 | UPDATE|COMPREHENSIVE function in infants?
QUESTIONS AND VERIFIED A. Renal blood flow reaches adult values by 1
SOLUTIONS/CORRECT ANSWERS|GET 100% month of age
ACCURATE!! B. Dosing recommendations for renally
eliminated drugs typically do not depend on
post-natal age
C. Near adult values in glomerular filtration rate
are reached by 2 weeks after birth
D. Tubular secretion and reabsorption processes
are immature at birth
4
Denosumab outcomes:
Practice questions for this set Don't know?
Learn Terms in this set (436)
1/7 Original
Study using Learn SL is a 31 week gestational age infant. She was
born two weeks ago. Her birthweight is 1.5
Decreases risk of hip/vertebral fractures kilograms. What is SL's post-natal and post-
menstrual age?
Reduces bone turnover markers A. 2 weeks post-natal age; 29 weeks post-
menstrual age
Increases cortical and trabecular bone mass and B. 2 weeks post-natal age; 33 weeks post-
strength menstrual age
C. 31 weeks post-natal age; 2 weeks post-
Rebound fractures in the vertebrae can occur menstrual age
after discontinuation D. 31 weeks post-natal age; 33 weeks post-
menstrual age
Effects are reversible since bone turnover E. 29 weeks post-natal age; 31 weeks post-
markers and BMD return to baseline within 12 menstrual age
months of d/c
B
Select the correct term
A neonate is defined as having what post-natal
1 age?
What type of mAb is denosumab? A. <2 years of age
B. ≤4 weeks of age
2 C. <121 days of age
D. <1 year of age
Lamotrigine clearance (increases/decreases) in
pregnancy B
3
,Which of the following could potentially alter B
the rate or extent of absorption in infants and
Which of the following is true regarding renal
neonates relative to adults?
function in infants?
A. Maturation in plasma proteins that bind to
A. Renal blood flow reaches adult values by 1
drugs
month of age
B. Differences in intragastric pH
B. Dosing recommendations for renally
C. Maturation in drug transporters that impact
eliminated drugs typically do not depend on
central nervous system penetration
post-natal age
D. Maturation in renal clearance
C. Near adult values in glomerular filtration rate
B are reached by 2 weeks after birth
D. Tubular secretion and reabsorption processes
Gastric emptying rate reaches adult capacity by
are immature at birth
what age?
A. 1 year of age D
B. 1 month of age
Which of the following equations is used
C. 6-8 months of age
commonly to estimate creatinine clearance in
D. 2 years of age
the pediatric population?
C A. Schwartz formula
B. Cockcroft-Gault formula
Which of the following factors can alter drug
C. Modification of Diet in Renal Disease (MDRD)
distribution in infants?
study formula
A. Less skin hydration
B. Changes in total body water and total body A
fat with age
Penicillins undergo glomerular filtration and
C. Drug-drug interactions that lead to drug
tubular secretion. Which of the following may
metabolism inhibition
be true about the half-life of elimination for
D. Differences in bacterial colonization of the
penicillins in infants?
intestines
A. No change in half-life of elimination
B B. Increased half-life of elimination due to
reduced glomerular filtration and tubular
The binding of drugs to plasma proteins
secretion
depends on which of the following factors?
C. Shorter half-life of elimination due to
A. Binding affinity for the protein
increased glomerular filtration and tubular
B. Timing of drug administration
secretion
C. Maturation in the expression of drug
metabolizing enzymes B
D. Gastric pH
The menstrual age is often commonly known as
A the ____ age. It is the time elapsed between the
first day of the last menstrual period and the
The pharmacological action of a drug is
day of delivery (most commonly reported in
attributed to which of the following?
weeks). The __-__ age is the age since birth
A. Plasma protein bound drug concentrations
B. Unbound drug concentrations gestational
post-natal
, Postnatal age + gestational age = _______ age What is the "week" range for children born
extremely preterm? Born before ___ weeks
postmenstrual
28
The _____ age is calculated by subtracting the
number of weeks born before 40 weeks from Low birth weight is below ____ kg
the post-natal age Very low birth weight is below ____ kg
Extremely low birth weight is below ____ kg
corrected
2.5
What is the corrected age of a child who is 28
1.5
months old (post-natal age) and was born at 28
1
weeks gestational age? (in months)
25 months
We have an expert-written solution to this
Put the appropriate age type for each box (in
problem!
alphabetical order)
postmenstrual age
gestational age What is the age range for neonates?
post-natal age
0-1 month (post-natal age)
corrected age
What is the age range for infants?
28 days-1 year
What is the age range for toddlers?
What is the age range for early childhood?
What is the age range for middle childhood?
What is the "week" range for children born post What is the age range for early adolescence?
term? What is the age range for late adolescence?
Greater than or equal to ____ weeks
1-2 years
42 2-5 years
6-11 years
What is the "week" range for children born full 12-18 years
term? 19-21 years
38-41 weeks Which of the following is not a reason that
What is the "week" range for children born pediatric drug development is difficult?
moderate-to-late preterm? (a) limited number of patients with each disease
32-37 weeks (technically not including 37, so 37 state/low rates of parental informed consent
weeks is kinda in a limbo) (b) you cannot ethically test medications in
What is the "week" range for children born very "healthy" child volunteers
preterm? (c) we already have plenty of good drugs for
28-32 weeks (not including 32 weeks) children
611 Exam 3 | UPDATE|COMPREHENSIVE function in infants?
QUESTIONS AND VERIFIED A. Renal blood flow reaches adult values by 1
SOLUTIONS/CORRECT ANSWERS|GET 100% month of age
ACCURATE!! B. Dosing recommendations for renally
eliminated drugs typically do not depend on
post-natal age
C. Near adult values in glomerular filtration rate
are reached by 2 weeks after birth
D. Tubular secretion and reabsorption processes
are immature at birth
4
Denosumab outcomes:
Practice questions for this set Don't know?
Learn Terms in this set (436)
1/7 Original
Study using Learn SL is a 31 week gestational age infant. She was
born two weeks ago. Her birthweight is 1.5
Decreases risk of hip/vertebral fractures kilograms. What is SL's post-natal and post-
menstrual age?
Reduces bone turnover markers A. 2 weeks post-natal age; 29 weeks post-
menstrual age
Increases cortical and trabecular bone mass and B. 2 weeks post-natal age; 33 weeks post-
strength menstrual age
C. 31 weeks post-natal age; 2 weeks post-
Rebound fractures in the vertebrae can occur menstrual age
after discontinuation D. 31 weeks post-natal age; 33 weeks post-
menstrual age
Effects are reversible since bone turnover E. 29 weeks post-natal age; 31 weeks post-
markers and BMD return to baseline within 12 menstrual age
months of d/c
B
Select the correct term
A neonate is defined as having what post-natal
1 age?
What type of mAb is denosumab? A. <2 years of age
B. ≤4 weeks of age
2 C. <121 days of age
D. <1 year of age
Lamotrigine clearance (increases/decreases) in
pregnancy B
3
,Which of the following could potentially alter B
the rate or extent of absorption in infants and
Which of the following is true regarding renal
neonates relative to adults?
function in infants?
A. Maturation in plasma proteins that bind to
A. Renal blood flow reaches adult values by 1
drugs
month of age
B. Differences in intragastric pH
B. Dosing recommendations for renally
C. Maturation in drug transporters that impact
eliminated drugs typically do not depend on
central nervous system penetration
post-natal age
D. Maturation in renal clearance
C. Near adult values in glomerular filtration rate
B are reached by 2 weeks after birth
D. Tubular secretion and reabsorption processes
Gastric emptying rate reaches adult capacity by
are immature at birth
what age?
A. 1 year of age D
B. 1 month of age
Which of the following equations is used
C. 6-8 months of age
commonly to estimate creatinine clearance in
D. 2 years of age
the pediatric population?
C A. Schwartz formula
B. Cockcroft-Gault formula
Which of the following factors can alter drug
C. Modification of Diet in Renal Disease (MDRD)
distribution in infants?
study formula
A. Less skin hydration
B. Changes in total body water and total body A
fat with age
Penicillins undergo glomerular filtration and
C. Drug-drug interactions that lead to drug
tubular secretion. Which of the following may
metabolism inhibition
be true about the half-life of elimination for
D. Differences in bacterial colonization of the
penicillins in infants?
intestines
A. No change in half-life of elimination
B B. Increased half-life of elimination due to
reduced glomerular filtration and tubular
The binding of drugs to plasma proteins
secretion
depends on which of the following factors?
C. Shorter half-life of elimination due to
A. Binding affinity for the protein
increased glomerular filtration and tubular
B. Timing of drug administration
secretion
C. Maturation in the expression of drug
metabolizing enzymes B
D. Gastric pH
The menstrual age is often commonly known as
A the ____ age. It is the time elapsed between the
first day of the last menstrual period and the
The pharmacological action of a drug is
day of delivery (most commonly reported in
attributed to which of the following?
weeks). The __-__ age is the age since birth
A. Plasma protein bound drug concentrations
B. Unbound drug concentrations gestational
post-natal
, Postnatal age + gestational age = _______ age What is the "week" range for children born
extremely preterm? Born before ___ weeks
postmenstrual
28
The _____ age is calculated by subtracting the
number of weeks born before 40 weeks from Low birth weight is below ____ kg
the post-natal age Very low birth weight is below ____ kg
Extremely low birth weight is below ____ kg
corrected
2.5
What is the corrected age of a child who is 28
1.5
months old (post-natal age) and was born at 28
1
weeks gestational age? (in months)
25 months
We have an expert-written solution to this
Put the appropriate age type for each box (in
problem!
alphabetical order)
postmenstrual age
gestational age What is the age range for neonates?
post-natal age
0-1 month (post-natal age)
corrected age
What is the age range for infants?
28 days-1 year
What is the age range for toddlers?
What is the age range for early childhood?
What is the age range for middle childhood?
What is the "week" range for children born post What is the age range for early adolescence?
term? What is the age range for late adolescence?
Greater than or equal to ____ weeks
1-2 years
42 2-5 years
6-11 years
What is the "week" range for children born full 12-18 years
term? 19-21 years
38-41 weeks Which of the following is not a reason that
What is the "week" range for children born pediatric drug development is difficult?
moderate-to-late preterm? (a) limited number of patients with each disease
32-37 weeks (technically not including 37, so 37 state/low rates of parental informed consent
weeks is kinda in a limbo) (b) you cannot ethically test medications in
What is the "week" range for children born very "healthy" child volunteers
preterm? (c) we already have plenty of good drugs for
28-32 weeks (not including 32 weeks) children
