Catabolism - ANSWER Metabolic pathways that break down molecules,
releasing energy.
Anabolism - ANSWER Metabolic pathways that construct molecules,
requiring energy.
Gluconeogenesis - ANSWER The formation of glucose from noncarbohydrate
sources.
Occurs mostly in the liver and kidneys.
Helps maintain glucose levels in the blood, which can be extracted for
metabolic needs.
What is the starting material for gluconeogenesis? - ANSWER Oxaloacetate
What are some non-carbohydrate precursors that are converted to oxaloacetate
in gluconeogenesis? - ANSWER Lactate and Pyruvate
What two amino acids cannot be broken down into oxaloacetate? What are they
broken down into? - ANSWER Leucine and Lysine, Acetyl-CoA.
How do gluconeogenesis enzymes relate to those of glycolysis? - ANSWER
Some of the same reversible enzymes of glycolysis are used in gluconeogenesis.
What is the advantage of catabolism and anabolism being separate pathways? -
ANSWER They can both be thermodynamically favored and independently
controlled.
Pyruvate Carboxylase - General Info - ANSWER 1st Step
Gluconeogenesis
ATP driven
Substrates: Pyruvate and HCO3-
Forms oxaloacetate
releasing energy.
Anabolism - ANSWER Metabolic pathways that construct molecules,
requiring energy.
Gluconeogenesis - ANSWER The formation of glucose from noncarbohydrate
sources.
Occurs mostly in the liver and kidneys.
Helps maintain glucose levels in the blood, which can be extracted for
metabolic needs.
What is the starting material for gluconeogenesis? - ANSWER Oxaloacetate
What are some non-carbohydrate precursors that are converted to oxaloacetate
in gluconeogenesis? - ANSWER Lactate and Pyruvate
What two amino acids cannot be broken down into oxaloacetate? What are they
broken down into? - ANSWER Leucine and Lysine, Acetyl-CoA.
How do gluconeogenesis enzymes relate to those of glycolysis? - ANSWER
Some of the same reversible enzymes of glycolysis are used in gluconeogenesis.
What is the advantage of catabolism and anabolism being separate pathways? -
ANSWER They can both be thermodynamically favored and independently
controlled.
Pyruvate Carboxylase - General Info - ANSWER 1st Step
Gluconeogenesis
ATP driven
Substrates: Pyruvate and HCO3-
Forms oxaloacetate
