NGN ATI PN Pharmacology 2023 A Exams STUDY
BUNDLE PACKAGE| Questions and Verified Answers|
100% Correct| Grade A
Pharmacokinetics refers to.... - ANSWERhow medications travel through the body
Medications undergo a variety of biochemical processes that result in __________,
__________,_________, and ____________. - ANSWERAbsorption, distribution,
metabolism, and excretion.
What is absorption? - ANSWERThe transmission of medications from the location of
administration to the bloodstream.
Parenteral? - ANSWERBy injection
Enteral - ANSWERThrough the GI tract
The rate of medication absorption determines - ANSWERhow soon the medication
will take effect
the amount of medication the body absorbs determines.... - ANSWERthe intensity of
its effects
The route of administration affects the ________ and amount of ______ -
ANSWERThe route of administration affects the rate and amount of absorption
Oral
Barriers to absortion - ANSWERMedications must pass through the layer of epithelial
cells that line the GI tract
Oral
Absorption Pattern: Varies greatly due to the following (5) - ANSWER1. Stability and
solubility of the medication
2.GI pH and emptying time
3. Presence of food in the stomach or intestines
4. Other concurrent medications
5. Forms of medications (enteric-coated pills, liquids)
Sublingual, Buccal
Barriers to absorption - ANSWERswallowing before dissolution allows gastric pH to
inactivate the medication
Sublingual, Buccal
Absorption Patterns - ANSWERQuick absorption systemically through highly vascular
mucous membranes
, Other mucous membranes (rectal, vaginal)
Barriers to absorption: - ANSWERpresence of stool/infectious material in the vagina
limits tissue contact
Other mucous membranes (rectal, vaginal)
absorption pattern: - ANSWEReasily absorbed w/ local and systemic effects
Inhalation via mouth, nose
Barriers to absorption: - ANSWERInspiratory effort
Inhalation via mouth, nose
Absorption patterns: - ANSWERRapid absorption through alveolar capillary networks
Intradermal, topical
Barriers to absorption - ANSWERClose proximity of epidermal cells
Intradermal, topical
Absorption Pattern (2) - ANSWER1. Slow, gradual absorption
2. Effects primarily local but can also systemic, especially with lipid - soluble
medications passing through subcutaneous fatty tissue
Subcutaneous, intramuscular
Barriers to absorption - ANSWERThere is no significant barrier.
Capillary walls have large spaces between cells that medications easily pass through
Subcutaneous, Intramuscular
Absorption Pattern (2) - ANSWERSolubility of the medication in water:
Highly soluble medications have rapid absorption (10 -30 min) ; poorly soluble
medications have slow absorption
Blood perfusion at the site of injections:
Sites with high blood perfusion have rapid abortion; sites with low blood perfusion
have slow absorption
Intravenous
Barriers to absorption - ANSWERNone
Intravenous
absorption pattern (2) - ANSWERImmediate: enters directly into the blood
Complete: reaches the blood in its entirety
Distribution - ANSWERis the transportation of medication to sites of action by bodily
fluids.
Factors that influence distribution are : (3) - ANSWER1. Circulation
2. Permeability of the cell membrane
3. Plasma protein binding
BUNDLE PACKAGE| Questions and Verified Answers|
100% Correct| Grade A
Pharmacokinetics refers to.... - ANSWERhow medications travel through the body
Medications undergo a variety of biochemical processes that result in __________,
__________,_________, and ____________. - ANSWERAbsorption, distribution,
metabolism, and excretion.
What is absorption? - ANSWERThe transmission of medications from the location of
administration to the bloodstream.
Parenteral? - ANSWERBy injection
Enteral - ANSWERThrough the GI tract
The rate of medication absorption determines - ANSWERhow soon the medication
will take effect
the amount of medication the body absorbs determines.... - ANSWERthe intensity of
its effects
The route of administration affects the ________ and amount of ______ -
ANSWERThe route of administration affects the rate and amount of absorption
Oral
Barriers to absortion - ANSWERMedications must pass through the layer of epithelial
cells that line the GI tract
Oral
Absorption Pattern: Varies greatly due to the following (5) - ANSWER1. Stability and
solubility of the medication
2.GI pH and emptying time
3. Presence of food in the stomach or intestines
4. Other concurrent medications
5. Forms of medications (enteric-coated pills, liquids)
Sublingual, Buccal
Barriers to absorption - ANSWERswallowing before dissolution allows gastric pH to
inactivate the medication
Sublingual, Buccal
Absorption Patterns - ANSWERQuick absorption systemically through highly vascular
mucous membranes
, Other mucous membranes (rectal, vaginal)
Barriers to absorption: - ANSWERpresence of stool/infectious material in the vagina
limits tissue contact
Other mucous membranes (rectal, vaginal)
absorption pattern: - ANSWEReasily absorbed w/ local and systemic effects
Inhalation via mouth, nose
Barriers to absorption: - ANSWERInspiratory effort
Inhalation via mouth, nose
Absorption patterns: - ANSWERRapid absorption through alveolar capillary networks
Intradermal, topical
Barriers to absorption - ANSWERClose proximity of epidermal cells
Intradermal, topical
Absorption Pattern (2) - ANSWER1. Slow, gradual absorption
2. Effects primarily local but can also systemic, especially with lipid - soluble
medications passing through subcutaneous fatty tissue
Subcutaneous, intramuscular
Barriers to absorption - ANSWERThere is no significant barrier.
Capillary walls have large spaces between cells that medications easily pass through
Subcutaneous, Intramuscular
Absorption Pattern (2) - ANSWERSolubility of the medication in water:
Highly soluble medications have rapid absorption (10 -30 min) ; poorly soluble
medications have slow absorption
Blood perfusion at the site of injections:
Sites with high blood perfusion have rapid abortion; sites with low blood perfusion
have slow absorption
Intravenous
Barriers to absorption - ANSWERNone
Intravenous
absorption pattern (2) - ANSWERImmediate: enters directly into the blood
Complete: reaches the blood in its entirety
Distribution - ANSWERis the transportation of medication to sites of action by bodily
fluids.
Factors that influence distribution are : (3) - ANSWER1. Circulation
2. Permeability of the cell membrane
3. Plasma protein binding
