GENERAL PHARMACOLOGY LATEST
ACTUAL EXAM QUESTIONS AND
DETAILED CORRECT ANSWERS | A+
GRADE
1.The main pharmacologic effect of the SSRIs is
A. increase levels of norepinephrine
B. increase levels of serotonin
C. decrease levels of norepinephrine
D. decrease levels of serotonin
E. decrease levels of dopamine Correct Answer B.
increase levels of serotonin
The pharmacologic effects of TCAs include
A. alpha-adrenergic blockade
B. antihistaminic
C. anticholinergic
D. sedation
E. all of the above Correct Answer E. all of the above
3. The serotonin syndrome is mainly associated with
overdosage of
A. tricyclic antidepressants
B. monoamine oxidase inhibitors
C. selective serotonin reuptake inhibitors
D. psychomotor stimulants
E. lithium Correct Answer E. lithium
,4.The main pharmacologic effects of TCAs on
neurotransmitter activity is
A. increase norepinephrine
B. increase acetylcholine
C. increase serotonin
D. increase norepinephrine and serotonin only
E. increase norepinephrine, acetylcholine, and serotonin
Correct Answer D. increase norepinephrine and serotonin
only
5. Venlafaxine (Effexor) is classified as
A. MAOI
B. TCA
C. SSRI
D. SNRI
E. psychomotor stimulant Correct Answer D. SNRI
6. Adverse effects of TCAs include
A. liver toxicity
B. cardiac arrhythmias
C. convulsions
D. postural hypotension
E. all of these Correct Answer E. all of these
7. Which of these represents the drug that is not correctly
matched with its drug classification?
A. paroxetine—SSRI
B. amitriptyline—TCA
C. methylphenidate—MAOI this is targets dop transporter
D. duloxetine—SNRI
,E. phenelzine—MAOI Correct Answer C.
methylphenidate—MAOI this is targets dop transporter
8. Which drug requires a dietary restriction for foods
containing tyramine?
A. nortriptyline (TCA)
B. tranylcypromine (MAOI)
C. venlafaxine (SNRI)
D. fluoxetine (SSRI)
E. methamphetamine Correct Answer B. tranylcypromine
(MAOI)
9. The site of action of diazepam (Valium) to relieve
anxiety is the
A. spinal cord
B. limbic system
C. reticular formation
D. basal ganglia
E. cerebellum Correct Answer B. limbic system
10. The antianxiety effect of buspirone (BuSpar) is
associated with
A. stimulation of DA receptors
B. stimulation of serotonin receptors
C. blockage of serotonin receptors
D. blockade of dopamine receptors
E. blockage of GABA receptors Correct Answer C.
blockage of serotonin receptors
11. Flumazenil (Romazicon) is used to reverse the
depressant effects of
, A. clozapine
B. alprazolam (benzodiazepine)
C. haloperidol
D. chlorpromazine
E. thiothixene Correct Answer alprazolam
(benzodiazepine)
12. What are the main areas at which benzodiazepines
exert their effects?
A. limbic system
B. cerebral cortex
C. reticular formation
D. spinal cord
E. all of these Correct Answer E. all of these
1. The study of drug absorption, distribution, metabolism,
and excretion is known as
A. pharmacotherapeutics
B. pharmacodynamics
C. pharmacokinetics
D. pharmacy
E. posology Correct Answer C
2. The medical situation when a particular drug should not
be administered is referred to as
A. side effect
B. adverse effect
C. drug allergy
D. contraindication
E. antagonism Correct Answer D
ACTUAL EXAM QUESTIONS AND
DETAILED CORRECT ANSWERS | A+
GRADE
1.The main pharmacologic effect of the SSRIs is
A. increase levels of norepinephrine
B. increase levels of serotonin
C. decrease levels of norepinephrine
D. decrease levels of serotonin
E. decrease levels of dopamine Correct Answer B.
increase levels of serotonin
The pharmacologic effects of TCAs include
A. alpha-adrenergic blockade
B. antihistaminic
C. anticholinergic
D. sedation
E. all of the above Correct Answer E. all of the above
3. The serotonin syndrome is mainly associated with
overdosage of
A. tricyclic antidepressants
B. monoamine oxidase inhibitors
C. selective serotonin reuptake inhibitors
D. psychomotor stimulants
E. lithium Correct Answer E. lithium
,4.The main pharmacologic effects of TCAs on
neurotransmitter activity is
A. increase norepinephrine
B. increase acetylcholine
C. increase serotonin
D. increase norepinephrine and serotonin only
E. increase norepinephrine, acetylcholine, and serotonin
Correct Answer D. increase norepinephrine and serotonin
only
5. Venlafaxine (Effexor) is classified as
A. MAOI
B. TCA
C. SSRI
D. SNRI
E. psychomotor stimulant Correct Answer D. SNRI
6. Adverse effects of TCAs include
A. liver toxicity
B. cardiac arrhythmias
C. convulsions
D. postural hypotension
E. all of these Correct Answer E. all of these
7. Which of these represents the drug that is not correctly
matched with its drug classification?
A. paroxetine—SSRI
B. amitriptyline—TCA
C. methylphenidate—MAOI this is targets dop transporter
D. duloxetine—SNRI
,E. phenelzine—MAOI Correct Answer C.
methylphenidate—MAOI this is targets dop transporter
8. Which drug requires a dietary restriction for foods
containing tyramine?
A. nortriptyline (TCA)
B. tranylcypromine (MAOI)
C. venlafaxine (SNRI)
D. fluoxetine (SSRI)
E. methamphetamine Correct Answer B. tranylcypromine
(MAOI)
9. The site of action of diazepam (Valium) to relieve
anxiety is the
A. spinal cord
B. limbic system
C. reticular formation
D. basal ganglia
E. cerebellum Correct Answer B. limbic system
10. The antianxiety effect of buspirone (BuSpar) is
associated with
A. stimulation of DA receptors
B. stimulation of serotonin receptors
C. blockage of serotonin receptors
D. blockade of dopamine receptors
E. blockage of GABA receptors Correct Answer C.
blockage of serotonin receptors
11. Flumazenil (Romazicon) is used to reverse the
depressant effects of
, A. clozapine
B. alprazolam (benzodiazepine)
C. haloperidol
D. chlorpromazine
E. thiothixene Correct Answer alprazolam
(benzodiazepine)
12. What are the main areas at which benzodiazepines
exert their effects?
A. limbic system
B. cerebral cortex
C. reticular formation
D. spinal cord
E. all of these Correct Answer E. all of these
1. The study of drug absorption, distribution, metabolism,
and excretion is known as
A. pharmacotherapeutics
B. pharmacodynamics
C. pharmacokinetics
D. pharmacy
E. posology Correct Answer C
2. The medical situation when a particular drug should not
be administered is referred to as
A. side effect
B. adverse effect
C. drug allergy
D. contraindication
E. antagonism Correct Answer D
