GMS6552 REVIEW EXAM 2 QUESTIONS AND ANSWERS WITH
COMPLETE SOLUTIONS GRADED A++
Problem Set 5: Oncogenes
What is the relationship between oncogenes and proto-oncogenes?
Proto-oncogenes are more carcinogenic than oncogenes
Oncogenes promote cancer while proto-oncogenes inhibit cancer
Oncogenes become proto-oncogenes during carcinogenesis
Proto-oncogenes become oncogenes during carcinogenesis
Proto-oncogenes become oncogenes during carcinogenesis
Which form(s) of oncogene activation involve(s) a mechanism that
will NEVER directly change the DNA sequence in a cell? Choose all that apply.
Mutation
Amplification
Rearrangement
Promoter insertion
Hypomethylation
Hypomethylation
Does the presence of oncogenes make it harder or easier to develop selective
anti-cancer agents with fewer side effects?
, Harder
Easier
Easier
What is the relationship between Ras and Myc mutations in cancer?
They work in a synergistic fashion to increase cell death.
They work in an additive fashion to increase cell death.
Ras mutations increase the lethality of Myc inhibitors.
Myc mutations increase the lethality of Ras inhibitors.
Myc mutations increase the lethality of Ras inhibitors.
Problem Set 6: Ion Channels I
What is the effect of one cycle of the sodium potassium pump in cells?
3 sodium ions in, 3 potassium ions out
3 sodium ions out, 3 potassium ions in
2 sodium ions in, 3 potassium ions out
2 sodium ions out, 3 potassium ions in
3 sodium ions in, 2 potassium ions out
3 sodium ions out, 2 potassium ions in
3 sodium ions out, 2 potassium ions in
The resting membrane potential of a neuron is _____.
12 mV
-90 mV
COMPLETE SOLUTIONS GRADED A++
Problem Set 5: Oncogenes
What is the relationship between oncogenes and proto-oncogenes?
Proto-oncogenes are more carcinogenic than oncogenes
Oncogenes promote cancer while proto-oncogenes inhibit cancer
Oncogenes become proto-oncogenes during carcinogenesis
Proto-oncogenes become oncogenes during carcinogenesis
Proto-oncogenes become oncogenes during carcinogenesis
Which form(s) of oncogene activation involve(s) a mechanism that
will NEVER directly change the DNA sequence in a cell? Choose all that apply.
Mutation
Amplification
Rearrangement
Promoter insertion
Hypomethylation
Hypomethylation
Does the presence of oncogenes make it harder or easier to develop selective
anti-cancer agents with fewer side effects?
, Harder
Easier
Easier
What is the relationship between Ras and Myc mutations in cancer?
They work in a synergistic fashion to increase cell death.
They work in an additive fashion to increase cell death.
Ras mutations increase the lethality of Myc inhibitors.
Myc mutations increase the lethality of Ras inhibitors.
Myc mutations increase the lethality of Ras inhibitors.
Problem Set 6: Ion Channels I
What is the effect of one cycle of the sodium potassium pump in cells?
3 sodium ions in, 3 potassium ions out
3 sodium ions out, 3 potassium ions in
2 sodium ions in, 3 potassium ions out
2 sodium ions out, 3 potassium ions in
3 sodium ions in, 2 potassium ions out
3 sodium ions out, 2 potassium ions in
3 sodium ions out, 2 potassium ions in
The resting membrane potential of a neuron is _____.
12 mV
-90 mV
