GMS6551 REVIEW FINAL EXAM QUESTIONS AND ANSWERS
WITH COMPLETE SOLUTIONS VERIFIED
Which definition best describes a lead compound?
- the compound that is used for in vivo experiments
- the compound that is used for clinical trials
- the first compound discovered to have the desired activity
- the compound that is FDA approved
The first compound discovered to have the desired activity
Which method of discovering a drug is least expensive?
- natural products
- high-throughput screening
- molecular docking
molecular docking
What is the name of the process that involves step-wise alteration of a drug to
improve its properties?
- Structure activity relationship
- ADME
- Target identification
- Assay development
Structure activity relationship
What was the estimated research and development expenses of pharma in 2016?
,60 billion
Which branch of pharmacology studies the effect of the body on drugs?
Pharmacokinetics
Which branch of pharmacology studies how patients respond differently to
drugs?
Pharmacogenetics
Which branch of pharmacology studies the desired effect of drugs on the body?
Pharmacodynamics
Which branch of pharmacology studies adverse effects of drugs on the body?
Toxicology
Which brand of pharmacology does excretion fall under?
Pharmacokinetics
Which is the chemical name for a popular OTC painkiller?
N-acetyl-para-aminophenol
What is the proprietary name for a popular OTC pain killer?
Tylenol
What is the non-proprietary name for a popular OTC painkiller?
Acetaminophen
Which of the following are OTC drugs?
- Codeine
- Diphenhydramine
- Loperamide
- Zocor
, - 6-tert-butyl-3-(4,5-dihydro-1H-imidazol_2_ylmethyl)-2,4-
dimethylphenol;hydrochloride
- Tadalafil
Diphenhydramine, Loperamide, 6-tert-butyl-3-(4,5-dihydro-1H-imidazol_2_ylmethyl)-2,4-
dimethylphenol;hydrochloride
Which of the following are prescription drugs?
- Codeine
- Diphenhydramine
- Loperamide
- Zocor
- 6-tert-butyl-3-(4,5-dihydro-1H-imidazol_2_ylmethyl)-2,4-
dimethylphenol;hydrochloride
- Tafadil
Codeine, Zocor, Tadalafil
Sally receives a year long prescription from her physician for low-dose codeine
that allows for 11 refills. Her pharmacist will refuse to honor the full prescription
because codeine is a schedule ? controlled substance
-I
- II
- III
III
Which stage of translational research is the first to utilize an FDA-approved drug?
T3 (Phase 4)
WITH COMPLETE SOLUTIONS VERIFIED
Which definition best describes a lead compound?
- the compound that is used for in vivo experiments
- the compound that is used for clinical trials
- the first compound discovered to have the desired activity
- the compound that is FDA approved
The first compound discovered to have the desired activity
Which method of discovering a drug is least expensive?
- natural products
- high-throughput screening
- molecular docking
molecular docking
What is the name of the process that involves step-wise alteration of a drug to
improve its properties?
- Structure activity relationship
- ADME
- Target identification
- Assay development
Structure activity relationship
What was the estimated research and development expenses of pharma in 2016?
,60 billion
Which branch of pharmacology studies the effect of the body on drugs?
Pharmacokinetics
Which branch of pharmacology studies how patients respond differently to
drugs?
Pharmacogenetics
Which branch of pharmacology studies the desired effect of drugs on the body?
Pharmacodynamics
Which branch of pharmacology studies adverse effects of drugs on the body?
Toxicology
Which brand of pharmacology does excretion fall under?
Pharmacokinetics
Which is the chemical name for a popular OTC painkiller?
N-acetyl-para-aminophenol
What is the proprietary name for a popular OTC pain killer?
Tylenol
What is the non-proprietary name for a popular OTC painkiller?
Acetaminophen
Which of the following are OTC drugs?
- Codeine
- Diphenhydramine
- Loperamide
- Zocor
, - 6-tert-butyl-3-(4,5-dihydro-1H-imidazol_2_ylmethyl)-2,4-
dimethylphenol;hydrochloride
- Tadalafil
Diphenhydramine, Loperamide, 6-tert-butyl-3-(4,5-dihydro-1H-imidazol_2_ylmethyl)-2,4-
dimethylphenol;hydrochloride
Which of the following are prescription drugs?
- Codeine
- Diphenhydramine
- Loperamide
- Zocor
- 6-tert-butyl-3-(4,5-dihydro-1H-imidazol_2_ylmethyl)-2,4-
dimethylphenol;hydrochloride
- Tafadil
Codeine, Zocor, Tadalafil
Sally receives a year long prescription from her physician for low-dose codeine
that allows for 11 refills. Her pharmacist will refuse to honor the full prescription
because codeine is a schedule ? controlled substance
-I
- II
- III
III
Which stage of translational research is the first to utilize an FDA-approved drug?
T3 (Phase 4)
