+ GRADED
Antibiotic
A drug that has the ability to kill or inhibit bacterial growth and replication
Which antibiotics have a beta-lactam ring in the molecular structure?
Penicillins, Carbapenems, Cephalosporins, and Monobactams
Which antibiotics are notable for side effects such as nephrotoxocity and
ototoxicity?
Amino-glycosides
Photosensitivity and teeth discoloration in children are most likely side effects
associated with what?
Tetracyclines
What antibiotic BEST classifies penicillins, cephalosporins, and carbapenems?
Cell Wall Inhibitors
Which antibiotic class disrupts folate metabolism in bacteria and is often
combined with trimethoprim?
Sulfonamides
Which antibiotic class inhibits the bacterial enzyme topoisomerase II (DNA
gyrase) and topoisomerase IV?
Fluoroquinolones
What medication is given alongside certain certain penicillins to prevent
breakdown of the antibiotic?
Beta-Lactamase inhibitors
Beta-lactamase inhibitors
A type of medication given alongside certain penicillins to prevent breakdown of the
antibiotic by the bacterial enzyme beta-lactamse.
Beta-lactamase inhibitors include clavulanic acid, sulbactam, and tazobactam
Fluoroquinolones
A class of antibiotics whose mechanism of action involves inhibition of the bacterial
enzyme topoisomerase II (DNA gyrase) and topoisomerase IV. Inhibition of these
enzymes prevents bacteria from properly replicating their DNA, resulting in cell death.
Often end with the suffix "-floxacin"
They are broad spectrum with excellent gram negative activity, including coverage of
Pseudomonas in some cases
Sulfonamides
A class of antibiotics whose mechanism of action involves inhibition of bacterial DNA
replication
Trimethoprim is often added to sulfonamides because it inhibits dihydrofolate reductase