+ GRADED
which describes the role of the T-lymphocyte cells in response to an antigen
coordinate specific immunity by stimulating the creation of antibodies and activate killer
T cells
what are the five types of antiretroviral drugs
reverse transcriptase inhibitors, integrase strand transfer inhibitors, protease inhibitors,
fusion inhibitors, CCR5 antagonist
what are the goals of antiretroviral treatment
1. maximal and durable suppression of viral load
2. restoration or preservation of immune function
3. improved quality of life
4. reduce transmission
5. prevent secondary infection
what is an example of reverse transcriptase inhibitors (NRTIs)
Zidovudine (AZT) - inhibits HIV replication
what is an example of non-nucleoside reverse transcriptase inhibitors (NNRTIs)
Nevirapine
what is an example of a protease inhibitor
indinavir
what are the lab test used to guide therapy
CD4 count (want higher)
plasma HIV RNA (Viral load) assays (want lower)
how often are the indications of HIV measured
every 3-6 months for the first few years and then yearly
why is HIV treatment a minimum of 3 drugs
more effective against resistant strains, reduces incidence of opportunistic infections,
reduction in viral load
what is a common side effect of indinavir
kidney stones
what are the three types of artificial active immunization
vaccines, toxoids
what are the treatment methods for cancer
1. surgery
2. radiation
3. drug therapy
what is the treatment of choice for disseminated cancers
drug therapy
what are the drug classes for cancer
cytotoxic agents (most often)
hormones and hormone antagonist
biologic response modifiers
targeted drugs