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1. A patient reports mild nausea within an hour after taking the first two doses of a
newly approved medication. Nausea is not listed among the known side effects of
this drug. What instructions will the provider give the patient? - ANSWER ✔
"Take the next dose with food and call the office if the nausea reoccurs or if other
symptoms develop."
2. A patient develops shortness of breath shortly after taking the initial dose of a
newly prescribed medication. The patient's heart rate is 86 beats/minute, the
respiratory rate is 24 breaths/minute, and the blood pressure is 120/70 mm Hg. The
prescriber will discontinue the drug based on the assumption the patient
experienced what medication induced effect? - ANSWER ✔ A side effect
3. A provider recommends genetic testing of a patient before prescribing a
medication. What response should the provider give when asked by the patient
about the purpose of genetic testing? - ANSWER ✔ "Such testing will tell us how
quickly your body is likely to metabolize, or process, the drug."
4. A patient is prescribed digoxin. Which screening will the provider order to
monitor for potential adverse effects from this drug? - ANSWER ✔ Serum
electrolytes
5.A provider considers prescribing tamoxifen for a woman with breast cancer.
Upon reviewing results of genetic testing, the prescriber notes that the patient has
variations in the CYP2Dy allele resulting in a deficiency of the CYP2D6
,isoenzymes. What action will this deficiency warrant in the prescribing of
tamoxifen, a CYP2D6 substrate? - ANSWER ✔ The tamoxifen will not be
prescribed.
6. A patient has taken a narcotic analgesic for chronic pain for several months. At a
follow-up appointment, the provider notes that the patient has been taking more
than the prescribed dosage. The patient has normal vital signs, is awake and alert,
and reports mild pain. What does the provider suspect is responsible for the
patient's response? - ANSWER ✔ This patient has developed pharmacodynamic
tolerance, which has increased the minimal effective concentration (MEC) needed
for analgesic effect
7. Which patient ethnic ancestry creates a risk factor that may result in minimal
beneficial response to tamoxifen therapy? - ANSWER ✔ French
8. Before initiating cetuximab therapy, the provider will order epidermal growth
factor receptor (EGFR) testing for the patient having which condition? - ANSWER
✔ Colorectal cancer
9. When considering the benefit of pharmacogenomics, what information should
the prescriber include when prescribing a new medication? - ANSWER ✔ Provide
definitions and possible examples of related idiosyncratic responses to this
medication
10. A provider has prescribed a female patient a medication that induces P-
glycoprotein (PGP). The provider will be particularly concerned about which
aspects of the patient's medical history? - ANSWER ✔ Intestinal problems, Kidney
function, Liver function
11. When prescribing medications to infants, it is important for the provider to
consider which fact? - ANSWER ✔ Breast-feeding infants are more likely to
develop toxicity when the mother is taking lipid-soluble drugs, Immaturity of renal
function in infancy causes infants to excrete drugs less efficiently. Infants have
immature livers, which slows drug metabolism, Infants are more sensitive to
medications that act on the central nervous system (CNS).
,12. What will the provider consider when prescribing two drugs that compete for
plasma albumin receptor sites? - ANSWER ✔ Binding of one or both agents will
be reduced, Plasma levels of free drug will rise, Plasma levels of free drug will fall
13. Which actions occur in most of the fatal medication errors? - ANSWER ✔
Giving a drug intravenously instead of intramuscularly, Administering a drug that
sounds like the prescribed drug, Writing a prescription illegibly
14. A patient is found to have a genetic deficiency in the biomarker CYP2C19. The
provider recognizes that prescribing clopidogrel will increase the patient's risk for
developing what serious conditions? - ANSWER ✔ Myocardial infarction, Stroke
15. A provider speaking to a class or a group of pregnant patients correctly teaches
that the highest risk of teratogen-induced gross malformations exists during which
time period - ANSWER ✔ During the first trimester
16. A pregnant patient asks her provider about the safe use of medications during
the third trimester. What will the provider tell her about drugs taken at this stage? -
ANSWER ✔ "They may need to be given in higher doses if they undergo renal
clearance."
17. A woman who breastfeeds her infant must take a prescription medication for 2
weeks. The medication is safe, but the patient wants to make sure her baby
receives as little of the drug as possible. What instructions will the prescriber give
the patient to best address her concerns? - ANSWER ✔ "Take the medication
immediately after breastfeeding your baby."
18. Which type of medication prescribed to a pregnant patient is more likely to
have effects on her fetus? - ANSWER ✔ Lipid-soluble drugs
19. A pregnant woman asks why more is not known about the teratogenic effects
of maternal medication ingestion during pregnancy. Which response will the
provider offer to address the patient's concern? - ANSWER ✔ "Clinical trials to
determine teratogenic effects would put the fetus at risk."
20. An infant developed a pruritic rash following exposure to an allergen. The
infant's parents ask the provider about using a topical antihistamine. What
, information should the provider use to address the parents' question? - ANSWER
✔ Applying an antihistamine to the skin can cause toxicity in this age group.
21. The parents of a child with asthma ask the provider why their child cannot use
oral corticosteroids more often, because they are so effective. The provider will
base the discussion with the parents on what fact concerning oral corticosteroids? -
ANSWER ✔ Chronic glucocorticoid use can inhibit physical growth
22. An infant is prescribed a medication that has a narrow therapeutic range and is
excreted by the kidneys. The provider will monitor closely for which effect? -
ANSWER ✔ Evidence of drug toxicity
23. A medication prescribed for a neonate is eliminated primarily by hepatic
metabolism. What action will the prescriber take to minimize risk to the infant? -
ANSWER ✔ Prescribe a dose that is relatively lower than an adult dose when
adjusted for body surface area
24. A pediatric provider is teaching nursing students to calculate medication doses
for children using a formula based on body surface area. Which statement by a
nursing student indicates understanding of the teaching? - ANSWER ✔ "This
formula helps approximate the first dose; other doses should be based on clinical
observations."
25. A child attending daycare is prescribed 750 mg of an antibiotic for 10 days.
The drug may be dosed in several ways and is available in two concentrations.
Which dosing regimen will the provider consider to best assure drug adherence? -
ANSWER ✔ 375 mg of a 500 mg/5 mL solution PO twice daily
26. A 5-year-old has gray teeth. When taking a medication history, the provider
will ask about previous use of which group of medications? - ANSWER ✔
Tetracyclines
27. A provider is concerned about renal function in an 84-year-old patient who is
taking several medications. What laboratory result will the provider order? -
ANSWER ✔ Creatinine clearance
28. An older adult patient with a history of forgetfulness will need to take multiple
drugs after discharge from the hospital. What provider action will most