GMS 6530 HYPERTENSION EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS GRADED A++

GMS 6530 HYPERTENSION EXAM QUESTIONS AND ANSWERS

WITH COMPLETE SOLUTIONS GRADED A++


Diuretics

- hydrochlorothiazide

- acute - lower BV

- chronic - lower TPR

- adverse - hypoK, alkalosis, increase LDL, gout, type II diabetes, ED

ACEI

- prils

- decrease TPR

- decrease aldosterone

- may increase bradykinin & prostaglandin

ACEI side effects

- 1st dose hypotension

- cough (5-20%)

- fetopathic renal impairment

- angioedema

- hyperkalemia

ARBS

, - sartans

- blocks ANGII receptors

- decreases TPR

ARBS side effects

- hypotension

- fetopathic potential

- hyperkalemia

CCB

- N, D, V

- block L-type channels

- decrease TPR - DHPs > D > V

- decrease HR - V >= D

- decrease contractility - V >= D

CCB side effects

- edema/fluid retention

- headache, flushing, dizziness (hypotension related)

- bradycardia

- reflex tachycardia (DHPs)

CCB precautions (V,D)

- SA or AV nodal abnormalities

- concurrent BB usage

- HF

- T1/2 increases with hepatic impairment