GMS6540 EXAM ACTUAL QUESTIONS AND VERIFIED CORRECT
ANSWERS
initiation/ transformation of a cell
Formation of a malignant tumor from a pre-neoplastic lesion
Formation of clinical cancer from a malignant tumor
metastasis of a clinical cancer
Genetic changes are required for which of the following to occur?
It would lead to increased activation of ERK
What effect would a G12V mutation in Ras have on ERK?
inactivate
Are cancers more likely to develop mutations that activate or inactivate Rb?
genetic instability
Metabolites of nicotine commonly result in DNA point mutations. Which type of DNA
instability is this an example of?
184
If a human cell underwent endoreduplication followed by failed cytokinesis, how many
chromosomes would you expect that cell to now contain?
Cancer cells must avoid it
Which of the following statements is true regarding apoptosis?
The switching of cancer cells from oxidative phosphorylation to aerobic
glycolysis
Which statement best describes the Warburg effect?
, more
A patient undergoes an FdG-PET scan. Willa. tumor contain more or less
18fluorodeoxyglucose than normal the surrounding tissue?
The process of creating new blood vessels from current blood vessels
Angiogenesis is _____________________.
beneficial
Is information harmful or beneficial to cancer?
tumor specific antigens
If a cell expresses a mutant form of EGFR, would this be considered a tumor-specific
antigen or a tumor-associated antigen?
They upregulate telomerase
Which statement best describes how cancer cells overcome the Hayflick limit?
Benzo[a]pyrene
What chemical causes the most cigarette-related DNA mutations
Burkitt's lymphoma
The Epstein-Barr virus, most famous for causing mononucleosis, also plays a prevalent
role int he formation of what type of cancer?
E6
What viral protein is capable of inhibiting p53?
Chemotherapy
Which class of cancer drugs is the least selective towards cancer cells?
small
Is chemotherapy generally more effective when tumors are small or large?
ANSWERS
initiation/ transformation of a cell
Formation of a malignant tumor from a pre-neoplastic lesion
Formation of clinical cancer from a malignant tumor
metastasis of a clinical cancer
Genetic changes are required for which of the following to occur?
It would lead to increased activation of ERK
What effect would a G12V mutation in Ras have on ERK?
inactivate
Are cancers more likely to develop mutations that activate or inactivate Rb?
genetic instability
Metabolites of nicotine commonly result in DNA point mutations. Which type of DNA
instability is this an example of?
184
If a human cell underwent endoreduplication followed by failed cytokinesis, how many
chromosomes would you expect that cell to now contain?
Cancer cells must avoid it
Which of the following statements is true regarding apoptosis?
The switching of cancer cells from oxidative phosphorylation to aerobic
glycolysis
Which statement best describes the Warburg effect?
, more
A patient undergoes an FdG-PET scan. Willa. tumor contain more or less
18fluorodeoxyglucose than normal the surrounding tissue?
The process of creating new blood vessels from current blood vessels
Angiogenesis is _____________________.
beneficial
Is information harmful or beneficial to cancer?
tumor specific antigens
If a cell expresses a mutant form of EGFR, would this be considered a tumor-specific
antigen or a tumor-associated antigen?
They upregulate telomerase
Which statement best describes how cancer cells overcome the Hayflick limit?
Benzo[a]pyrene
What chemical causes the most cigarette-related DNA mutations
Burkitt's lymphoma
The Epstein-Barr virus, most famous for causing mononucleosis, also plays a prevalent
role int he formation of what type of cancer?
E6
What viral protein is capable of inhibiting p53?
Chemotherapy
Which class of cancer drugs is the least selective towards cancer cells?
small
Is chemotherapy generally more effective when tumors are small or large?
