GMS6540: ANTIBACTERIALS 1 EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS VERIFIED

GMS6540: ANTIBACTERIALS 1 EXAM QUESTIONS AND

ANSWERS WITH COMPLETE SOLUTIONS VERIFIED

purpose of chemotherapy

-treatment of active infection

-prophylaxis = prevent spread of disease

selective toxicity/drug targets

1. bacterial = cell wall/membrane, protein synthesis, DNA/RNA synthesis

2. fungal = cell wall/membrane, steroid synthesis

3. viral = DNA/RNA synthesis, absorption/processing/assembly

4. parasitic

why so many antibiotics?

-spectrum

-resistance

-pharmacokinetics

-adverse effects

-drug interactions

bacterial therapeutic examples

-gram +/gram -

-acid-fast

-aerobic/anaerobic

-intracellular

therapeutics

, -you wanna pick the drug that fits the bug

-bacteria;

-fungal

-viral

-parasitic

viral therapeutic examples

-herpes

-hepatitis

-HIV

parasitic therapeutic examples

-protozoal

-worm

bacterial physiology and pharmacology

-gram +/gram - bacteria

-mycobacteria = different cell wall structure

-mycoplasma = lacks a cell wall

-aerobic/anaerobic

-intracellular = chlamydia, mycobacteria, rickettsia

gram-positive bacteria

-stain purple

-have thick peptidoglycan layer

-penicillin example

gram-negative bacteria