GMS6540 REVIEW EXAM 2 EXAM QUESTIONS AND ANSWERS
WITH COMPLETE SOLUTIONS VERIFIED LATEST UPDATE
Which component of the CRISPR-Cas9 system determines the location of gene
edits?
gRNA
Which of the following is an aminoglycoside?
gentamycin
With which drug would an aminoglycoside be synergistic?
penicillin
Hearing loss as a side effect is most common with which drug?
gentamycin
Which drug is active against gram positive bacteria as well as mycoplasma?
tetracycline
Which macrolide would be expected to have better patient compliance when
taken orally?
azithromycin
Which antibiotic may, in some cases, exert its effect inside of human cells?
doxycycline
An ambulance brings in a patient that is in a non-responsive patient suffering
from sepsis due to a S. aureus infection. You go to administer amoxicillin but
notice that they are wearing a medical bracelet saying that they are allergic to
penicillins. Which drug is the most likely alternative to be used for this patient?
, clindamycin
Which mechanism best describes the cause of gray baby syndrome in the use of
chloramphenicol?
the drug is cleared slower from babies than in adults
Which part of the bacterial life cycle is most strongly inhibited by ciprofloxacin?
replication
In general, do we have more drug options for treating aerobic or anaerobic
bacterial infections?
aerobic?
Would isoniazid be expected to increase or decrease the activity of drug
metabolizing enzymes toward other drugs?
decrease
Two patients that are identical in every way except that one is a slow acetylator
and the other is a fast acetylator of isoniazid are being treated for tuberculosis.
Patient A is receiving 15 mg/kg once per week and Patient B is receiving 15 mg/kg
three times per week. Which patient is the fast acetylator?
Patient B
Which bacterial cell function is most directly inhibited by rifampin?
transcription
What is the primary reason that treatment for mycoplasma infection involves
many drugs taken simultaneously?
to prevent resistance
WITH COMPLETE SOLUTIONS VERIFIED LATEST UPDATE
Which component of the CRISPR-Cas9 system determines the location of gene
edits?
gRNA
Which of the following is an aminoglycoside?
gentamycin
With which drug would an aminoglycoside be synergistic?
penicillin
Hearing loss as a side effect is most common with which drug?
gentamycin
Which drug is active against gram positive bacteria as well as mycoplasma?
tetracycline
Which macrolide would be expected to have better patient compliance when
taken orally?
azithromycin
Which antibiotic may, in some cases, exert its effect inside of human cells?
doxycycline
An ambulance brings in a patient that is in a non-responsive patient suffering
from sepsis due to a S. aureus infection. You go to administer amoxicillin but
notice that they are wearing a medical bracelet saying that they are allergic to
penicillins. Which drug is the most likely alternative to be used for this patient?
, clindamycin
Which mechanism best describes the cause of gray baby syndrome in the use of
chloramphenicol?
the drug is cleared slower from babies than in adults
Which part of the bacterial life cycle is most strongly inhibited by ciprofloxacin?
replication
In general, do we have more drug options for treating aerobic or anaerobic
bacterial infections?
aerobic?
Would isoniazid be expected to increase or decrease the activity of drug
metabolizing enzymes toward other drugs?
decrease
Two patients that are identical in every way except that one is a slow acetylator
and the other is a fast acetylator of isoniazid are being treated for tuberculosis.
Patient A is receiving 15 mg/kg once per week and Patient B is receiving 15 mg/kg
three times per week. Which patient is the fast acetylator?
Patient B
Which bacterial cell function is most directly inhibited by rifampin?
transcription
What is the primary reason that treatment for mycoplasma infection involves
many drugs taken simultaneously?
to prevent resistance
